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APOE / Apolipoprotein E

apolipoprotein E

Chylomicron remnants and very low density lipoprotein (VLDL) remnants are rapidly removed from the circulation by receptor-mediated endocytosis in the liver. Apolipoprotein E, a main apoprotein of the chylomicron, binds to a specific receptor on liver cells and peripheral cells. ApoE is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. The APOE gene is mapped to chromosome 19 in a cluster with APOC1 and APOC2. Defects in apolipoprotein E result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants.

Gene Name: apolipoprotein E
Synonyms: APOE, AD2, Apo-E, Apolipoprotein E3, Apolipoprotein E, LDLCQ5, LPG
Target Sequences: NM_000041 NP_000032.1 P02649

Publications (2)

1
A proteomic approach for the diagnosis of bacterial meningitis. Jesse S, Steinacker P, Lehnert S, Sdzuj M, Cepek L, Tumani H, Jahn O, Schmidt H, Otto M. PloS one. 2010 5:e10079. (WB) [PubMed:20386697] [PMC:PMC2851643]
2
Longterm Increased S100B Enhances Hippocampal Progenitor Cell Proliferation in a Transgenic Mouse Model. Leticia Rodrigues, Krista Minéia Wartchow, Michael Buchfelder, Diogo Onofre Souza, Carlos-Alberto Gonçalves, Andrea Kleindienst. International journal of molecular sciences. 2022 August;23: [Full Text Article] [PubMed:36076994] [PMC:PMC9455494]

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APOE / Apolipoprotein E Antibody - Anti-APOE / Apolipoprotein E antibody IHC staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
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Neuroscience
APOE / Apolipoprotein E Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
0.05 mg/$545
APOE / Apolipoprotein E Antibody - Human Adrenal: Formalin-Fixed, Paraffin-Embedded (FFPE)
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Neuroscience
APOE / Apolipoprotein E Goat anti-Human Polyclonal (aa305-317) Antibody
Human
IHC-P, Peptide-ELISA, WB
Unconjugated
50 µg/$485
APOE / Apolipoprotein E Antibody - Anti-APOE / Apolipoprotein E antibody IHC of human adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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Neuroscience
APOE / Apolipoprotein E Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
100 µl/$485
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APOE / Apolipoprotein E Rabbit anti-Human Polyclonal Antibody
Human
ELISA, ICC, IHC, IHC-Fr
Unconjugated
1 ml/$549
APOE / Apolipoprotein E Antibody - Adrenal, Human: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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APOE / Apolipoprotein E Mouse anti-Human Monoclonal (Biotin) (WUE-4) Antibody
Human
ELISA, IHC, IHC-P, WB
Biotin Conjugated
0.1 ml/$416
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APOE / Apolipoprotein E Mouse anti-Human Monoclonal Antibody
Human
WB
Unconjugated
100 µl/$838
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APOE / Apolipoprotein E Goat anti-Human Polyclonal Antibody
Human
ELISA
Unconjugated
1 mg/$626
APOE / Apolipoprotein E Antibody
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APOE / Apolipoprotein E Mouse anti-Human Monoclonal (1F9) Antibody
Human
IHC, IP, WB
Unconjugated
100 µg/$454
APOE / Apolipoprotein E Antibody - Western Blot (non-reducing) of Apolipoprotein E / APOE antibody
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APOE / Apolipoprotein E Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
50 µg/$356; 100 µg/$396
APOE / Apolipoprotein E Antibody - Biotinylated Anti-Human ApoE3 Western Blot Unreduced
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APOE / Apolipoprotein E Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
25 µg/$356; 50 µg/$396
APOE / Apolipoprotein E ELISA Kit
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Competitive EIA
96-Well Microplate
Rat
15.6 - 1000 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum, Tissue Homogenates
1 Plate/$734
APOE / Apolipoprotein E ELISA Kit
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Competitive EIA
96-Well Microplate
Mouse
6.25 - 400 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum, Tissue Homogenates
1 Plate/$675
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HEK 293 Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
35.3kD
10 µg/$218; 50 µg/$240; 500 µg/$343; 1 mg/$409
APOE / Apolipoprotein E ELISA Kit
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Sandwich
96-Well Strip Plate
Monkey
6.25 - 400 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
APOE / Apolipoprotein E ELISA Kit
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Sandwich
96-Well Microplate
Mouse
1.56 - 100 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$626
APOE / Apolipoprotein E ELISA Kit
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Sandwich
96-Well Strip Plate
Mouse
15.63 - 1000 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$782
APOE / Apolipoprotein E Protein
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Yeast
6His, N-terminus
35.9 kD
100 µg/$499; 20 µg/$364; 1 mg/$1,683
APOE / Apolipoprotein E Antibody - Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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APOE / Apolipoprotein E Rabbit anti-Human Polyclonal (aa81-130) Antibody
Mouse, Human
IHC, IHC-P, WB
Unconjugated
100 µl/$485
APOE / Apolipoprotein E Antibody - Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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Neuroscience
APOE / Apolipoprotein E Mouse anti-Human Monoclonal (aa100-150) (4E4) Antibody
Human
ELISA, IHC, IHC-P, IP, WB
Unconjugated
0.1 ml/$460
APOE / Apolipoprotein E Antibody - Anti-APOE / Apolipoprotein E antibody IHC of human adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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Neuroscience
APOE / Apolipoprotein E Goat anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$460
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APOE / Apolipoprotein E Mouse anti-Human Monoclonal (aa140-160) (8B65) Antibody
Human
ELISA, Flo, IHC, IP, WB
Unconjugated
100 µl/$725
APOE / Apolipoprotein E ELISA Kit
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Sandwich
96-Well Strip Plate
Pig
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$779
APOE / Apolipoprotein E Protein
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HEK 293 Cells
His, N-Terminal
~37 kDa
10 µg/$289; 50 µg/$360
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E. coli
6His, N-terminus
38 kD
1 mg/$1,679; 100 µg/$500; 20 µg/$364
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APOE / Apolipoprotein E Mouse anti-Human Monoclonal (Low Endotoxin) (WUE-4) Antibody
Human
ELISA, WB
Unconjugated, Low Endotoxin
0.5 mg/$697
Viewing 1-25 of 206 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).