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ADRA2A

adrenoceptor alpha 2A

Alpha-2-adrenergic receptors are members of the G protein-coupled receptor superfamily. They include 3 highly homologous subtypes: alpha2A, alpha2B, and alpha2C. These receptors have a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system. Studies in mouse revealed that both the alpha2A and alpha2C subtypes were required for normal presynaptic control of transmitter release from sympathetic nerves in the heart and from central noradrenergic neurons; the alpha2A subtype inhibited transmitter release at high stimulation frequencies, whereas the alpha2C subtype modulated neurotransmission at lower levels of nerve activity. This gene encodes alpha2A subtype and it contains no introns in either its coding or untranslated sequences.

Gene Name: adrenoceptor alpha 2A
Family/Subfamily: GPCR , Adrenergic
Synonyms: ADRA2A, Alpha-2A adrenoreceptor, Alpha-2AAR, Alpha-2AAR subtype C10, ADRA2, ADRA2R, ADRAR, Adrenoceptor alpha 2A, Alpha 2a, Alpha(2A)-AR, Alpha2a, ALPHA2AAR, Alpha-2A adrenoceptor, Adrenergic alpha 2a receptor, Adrenergic alpha 2a receptor, Alpha-2A adrenergic receptor
Target Sequences: NM_000681 NP_000672.3 P08913

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Products
Antibodies (32)
Primary (32)
ADRA2A (32)
Human (30)
Mouse (15)
Rat (14)
Bat (1)
Bovine (2)
Chicken (1)
Guinea pig (2)
Horse (1)
Monkey (2)
Orangutan (3)
Pig (2)
Rabbit (3)
Sheep (1)
Zebrafish (1)
IHC (9)
IHC-P (4)
WB (22)
ELISA (8)
ICC (2)
IF (12)
IP (3)
Peptide-ELISA (7)
rabbit (31)
goat (1)
Product Group
IHCPlus (1)
IgG (17)
polyclonal pc (32)
Biotin Conjugated (2)
FITC Conjugated (2)
HRP Conjugated (2)
Magnetic beads Conjugated (1)
Sepharose Conjugated (1)
Unconjugated (24)
C-Terminus (4)
aa324-373 (4)
250-330 aa, Internal (1)
300-380 aa, C-terminal (1)
Arg361 (1)
Internal (1)
aa118-152 (1)
aa213-228 (1)
aa223-256 (1)
aa246-258 (1)
aa281-330 (1)
aa312-361 (1)
aa331-380 (1)
aa414-431 (1)
No (32)
ADRA2A Antibody - Anti-ADRA2A antibody IHC of human colon, submucosal plexus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.
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ADRA2A Rabbit anti-Human Polyclonal (aa331-380) Antibody
Mouse, Rat, Human
IF, IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$460
ADRA2A Antibody - 1:100 staining mouse intestine tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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ADRA2A Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
ADRA2A Antibody - ADRA2A antibody Western Blot of Fetal Thymus.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ADRA2A Rabbit anti-Human Polyclonal (aa324-373) Antibody
Human
WB
Unconjugated
100 µl/$424
ADRA2A Antibody - Western blot of AR alpha2A antibody
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ADRA2A Rabbit anti-Human Polyclonal (300-380 aa, C-terminal) Antibody
Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
ADRA2A Antibody - IHC of AR 2A (R361) pAb in paraffin-embedded human testis tissue.
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ADRA2A Rabbit anti-Human Polyclonal (Arg361) Antibody
Mouse, Rat, Human
IF, IHC, IHC-P, WB
Unconjugated
50 µl/$321; 100 µl/$403
ADRA2A Antibody - Peptide - + Immunohistochemistry analysis of paraffin-embedded human testis tissue using Adrenergic Receptor a-2A antibody.
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ADRA2A Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
100 µg/$357
ADRA2A Antibody - Western blot analysis of Alpha-2A Adrenergic Receptor expression in HepG2 (A); mouse heart (B); rat heart (C) whole cell lysates.
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ADRA2A Rabbit anti-Human Polyclonal (Internal) Antibody
Human
ICC, IF, IP, WB
Unconjugated
100 µl/$299
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ADRA2A Rabbit anti-Rat Polyclonal Antibody
Rat
ICC, IF, IHC
Unconjugated
50 µl/$491
ADRA2A Antibody - Western blot of AR-alpha2A antibody
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ADRA2A Rabbit anti-Human Polyclonal (250-330 aa, Internal) Antibody
Human
ELISA, IF, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
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ADRA2A Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Rabbit, Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
100 µg/$564
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ADRA2A Rabbit anti-Human Polyclonal (aa414-431) Antibody
Rabbit, Mouse, Guinea pig, Bovine, Rat, Pig, Human, Monkey
IHC, IHC-P, WB
Unconjugated
100 µg/$723
ADRA2A Antibody - Western blot analysis of the lysates from Jurkat cells using Adrenergic Receptor α-2A antibody.
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ADRA2A Rabbit anti-Human Polyclonal (aa312-361) Antibody
Mouse, Rat, Human
IHC, Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
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ADRA2A Rabbit anti-Human Polyclonal Antibody
Human
IF, WB
Unconjugated
100 µl/$386
ADRA2A Antibody - Peptide - + Immunofluorescence analysis of LOVO cells, using ADRA2A antibody.
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ADRA2A Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF
Unconjugated
100 µg/$357
ADRA2A Antibody - Immunofluorescence analysis of LOVO cells, using ADRA2A Antibody. The picture on the right is blocked with the synthesized peptide.
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ADRA2A Rabbit anti-Human Polyclonal (aa281-330) Antibody
Human
IF, Peptide-ELISA
Unconjugated
50 µl/$334; 100 µl/$397
ADRA2A Antibody - ADRA2A antibody immunofluorescence analysis of paraformaldehyde fixed MCF7 cells, permeabilized with 0.15% Triton. Primary incubation 1hr (10ug/ml) followed by Alexa Fluor 488 secondary antibody (2ug/ml), showing membrane staining. The nuclear stain is DAPI (blue). Negative control: Unimmunized goat IgG (10ug/ml) followed by Alexa Fluor 488 secondary antibody (2ug/ml).
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ADRA2A Goat anti-Human Polyclonal (aa246-258) Antibody
Human
IF, Peptide-ELISA
Unconjugated
100 µg/$503
ADRA2A Antibody - All lanes: Anti-ADRA2A Antibody (N-Term) at 1:2000 dilution. Lane 1: HeLa whole cell lysate. Lane 2: Jurkat whole cell lysate. Lane 3: LoVo whole cell lysate. Lane 4: MCF-7 whole cell lysate. Lane 5: PANC-1 whole cell lysate Lysates/proteins at 20 ug per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1:10000 dilution. Predicted band size: 49 kDa. Blocking/Dilution buffer: 5% NFDM/TBST.
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ADRA2A Rabbit anti-Human Polyclonal (aa118-152) Antibody
Human
Peptide-ELISA, WB
Unconjugated
200 µl/$393
ADRA2A Antibody - Anti- (DANRE) adra2a Antibody at 1:2000 dilution + zebrafish muscle lysates Lysates/proteins at 20 ug per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution Predicted band size : 44 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
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ADRA2A Rabbit anti-Zebrafish Polyclonal (aa223-256) Antibody
Zebrafish
Peptide-ELISA, WB
Unconjugated
400 µl/$393
ADRA2A Antibody - Immunofluorescent analysis of MCF-7 cells using ADRA2A Antibody at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
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ADRA2A Rabbit anti-Human Polyclonal Antibody
Human
ELISA
Unconjugated
50 µg/$294; 100 µg/$360
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ADRA2A Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA
HRP Conjugated
50 µg/$294; 100 µg/$360
ADRA2A Antibody -  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ADRA2A Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Mouse, Rat, Human
WB
Unconjugated
100 µg/$380
ADRA2A Antibody - WB of ADRA2A antibody. Lane 1: HELA Cell Lysate. Lane 2: PANC Cell Lysate.
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ADRA2A Rabbit anti-Human Polyclonal (aa213-228) Antibody
Chicken, Sheep, Bovine, Rat, Pig, Horse, Bat, Rabbit, Mouse, Guinea pig, Human, Monkey
WB
Unconjugated
10 µg/$318; 100 µg/$470
ADRA2A Antibody - Western blot analysis of extracts of various cells.
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ADRA2A Rabbit anti-Human Polyclonal Antibody
Mouse, Human
WB
Unconjugated
20 µl/$275; 100 µl/$389
ADRA2A Antibody - Western blot analysis of extracts of various cell lines, using ADRA2A antibody at 1:1000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking. An ECL Kit was used for detection and the exposure time was 20s.
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ADRA2A Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
20 µl/$275; 100 µl/$389
ADRA2A Antibody - Western blot analysis of extracts. (35ug) from different cell lines or tissues by using anti-ADRA2A rabbit polyclonal antibody .
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ADRA2A Rabbit anti-Human Polyclonal Antibody
Mouse, Human
WB
Unconjugated
100 µl/$414
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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).