Target
Human ADRA2A
Synonyms
ADRA2A | Alpha-2A adrenoreceptor | Alpha-2AAR | Alpha-2AAR subtype C10 | ADRA2 | ADRA2R | ADRAR | Adrenoceptor alpha 2A | Alpha 2a | Alpha(2A)-AR | Alpha2a | ALPHA2AAR | Alpha-2A adrenoceptor | Adrenergic alpha 2a receptor | Adrenergic alpha 2a receptor | Alpha-2A adrenergic receptor
Reactivity
Human
(tested or 100% immunogen sequence identity)
Conjugations
Unconjugated.
Also available conjugated with
FITC,
Biotin,
HRP.
Immunogen
Recombinant Human Alpha-2A adrenergic receptor protein (218-374AA)
Specificity
Alpha-2 adrenergic receptors mediate the catecholamine-induced inhibition of adenylate cyclase through the action of G proteins. The rank order of potency for agonists of this receptor is oxymetazoline > clonidine > epinephrine > norepinephrine > phenylephrine > dopamine > p-synephrine > p-tyramine > serotonin = p-octopamine. For antagonists, the rank order is yohimbine > phentolamine = mianserine > chlorpromazine = spiperone = prazosin > propanolol > alprenolol = pindolol.