Products
Research Areas
COVID-19
Resources
Login
Quick Order
Cart Cart lightblue
Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order
Contact Us

Locations


Orders Processing,
Shipping & Receiving,
Warehouse

2 Shaker Rd Suites
B001/B101
Shirley, MA 01464


Production Lab

Floor 6, Suite 620
20700 44th Avenue W
Lynnwood, WA 98036

Telephone Numbers



Tel: +1 (800) 227-6666


Contact Us



Additional Contact Details

Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order
PathPlusTM EP300 / p300 Antibodies
EP300 is a histone acetyltransferase that regulates transcription via chromatin remodeling. It acetylates all four core histones in nucleosomes. EP300 mediates cAMP-gene regulation by binding specifically to phosphorylated CREB protein. It also plays a role as a coactivator of NEUROD1-dependent transcription of the secretin and p21 genes and controls terminal differentiation of cells in the intestinal epithelium. EP300 can also promote cardiac myocyte enlargement. In infectious disease, it binds to and may be involved in the transforming capacity of the adenovirus E1A protein, and in case of HIV-1 infection, it is recruited by the viral protein Tat. It regulates Tat's transactivating activity and may help inducing chromatin remodeling of proviral genes. In immunohistochemistry, EP300 has nuclear and cytoplasmic positivity in a majority of tissues throughout the body. References: The UniProt Consortium. Nucleic Acids Res. 47: D506-515 (2019); Nucleic Acids Res. 2016 Jan 4;44(D1):D733-45, PMID:26553804;

2 PathPlusTM Antibodies
☰ Filters
Antibodies (2)
Primary (2)
EP300 / p300 (2)
Human (2)
Mouse (1)
Rat (1)
Mustelid (1)
Primate (1)
IHC-P (2)
WB (2)
IF (1)
IP (1)
Peptide-ELISA (1)
rabbit (1)
mouse (1)
Product Group
PathPlus Cancer (2)
IgG (1)
IgG1,k (1)
monoclonal mc (1)
polyclonal pc (1)
RW128 (1)
Unconjugated (2)
aa1-50 (1)
aa1572-2371 (1)
No (2)
EP300 / p300 Antibody - Human Colon: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
Cancer
EP300 / p300 Mouse anti-Human Monoclonal (aa1572-2371) (RW128) Antibody
Mouse, Rat, Mustelid, Primate, Human
IF, IHC-P, IP, WB
Unconjugated
0.1 mg/$460
EP300 / p300 Antibody - Anti-EP300 / p300 antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.
Select
Cancer
EP300 / p300 Rabbit anti-Human Polyclonal (aa1-50) Antibody
Human
IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$440
Viewing 1-2 of 2 product results