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| Catalog Number | Size | Price |
|---|---|---|
| LS-B11805-200 | 200 µl | $440 |
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PathPlus™ Monoclonal Mouse anti‑Human TUBB / Beta Tubulin Antibody (IHC, IF, WB) LS‑B11805
PathPlus™ Monoclonal Mouse anti‑Human TUBB / Beta Tubulin Antibody (IHC, IF, WB) LS‑B11805
Note: This antibody replaces LS-C161724
Antibody:
TUBB / Beta Tubulin Mouse anti-Human Monoclonal Antibody
Application:
IHC, IHC-P, IF, WB
Reactivity:
Human, Mouse
Format:
Unconjugated, Unmodified
Toll Free North America
(800) 227-6666
(800) 227-6666For Research Use Only
Overview
Antibody:
TUBB / Beta Tubulin Mouse anti-Human Monoclonal Antibody
Application:
IHC, IHC-P, IF, WB
Reactivity:
Human, Mouse
Format:
Unconjugated, Unmodified
Specifications
Description
TUBB (beta tubulin class I) is protein that forms a dimer with alpha tubulin to act as a major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain (TUBB) and one at a non-exchangeable site on the alpha chain. Inherited TUBB mutations lead to development brain defects including cortical dysplasia, while somatic mutations are correlated with drug resistance in cancer. In immunohistochemistry, TUBB has variable degrees of cytoplasmic positivity in all tissues.
References: Hum Genet. 1994 Jan;93(1):42-6, PMID: 8270253; Biochem Biophys Res Commun. 2016 Aug 5;476(4):273-279, PMID: 27233604; J Biomol Struct Dyn. 2015;33(12):2530-40, PMID: 26081685; Mol Cancer Ther. 2011 Aug;10(8):1419-29, PMID: 21653684
Target
Human TUBB / Beta Tubulin
Synonyms
TUBB | Beta Tubulin | Beta 5-tubulin | Beta-4 tubulin | Beta1-tubulin | M40 | Tubulin beta-5 chain | Beta Ib tubulin | Class I beta-tubulin | OK/SW-cl.56 | TUBB5 | Tubulin beta chain | Tubulin beta polypeptide | Tubulin beta-1 chain | Tubulin, beta class I | Tubulin, beta polypeptide
Host
Mouse
Reactivity
Human, Mouse
(tested or 100% immunogen sequence identity)
Predicted
Rat, Hamster, Pig, Chicken, Xenopus, Cow (at least 90% immunogen sequence identity)
Clonality
IgG2b
Monoclonal
Conjugations
Unconjugated
Purification
Protein G purified
Modifications
Unmodified
Applications
- IHC
- IHC - Paraffin (1:50)
- Immunofluorescence (1:10 - 1:50)
- Western blot (1:100 - 1:500)
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Presentation
PBS, 0.09% Sodium Azide
Storage
Maintain refrigerated at 2°C to 8°C for up to 6 months. For long term storage store at -20°C.
Restrictions
For research use only. Intended for use by laboratory professionals.
About TUBB / Beta Tubulin
Validation
Human Thymus: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Thymus: Formalin-Fixed, Paraffin-Embedded (FFPE)
See More About...
LSBio Ratings
PathPlus™ TUBB / Beta Tubulin Antibody for IHC, IF/Immunofluorescence, WB/Western LS-B11805 has an LSBio Rating of
Laboratory Validation Score (5)
Learn more about The LSBio Ratings Algorithm
Publications (0)
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Species:
Human, Mouse, Rat, Bovine, Rabbit, Chicken, Frog
Applications:
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Species:
Human, Mouse, Rat
Applications:
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Species:
Human
Applications:
IHC - Paraffin, ICC, Western blot
Species:
Human, Mouse, Rat, Bovine, Rabbit, Chicken, Frog
Applications:
IHC, IHC - Paraffin, Immunofluorescence, Western blot
Species:
Human, Monkey, Mouse, Rat
Applications:
IHC, IHC - Paraffin, ICC, Immunofluorescence
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 12/29/2024
Date Requested: 12/29/2024
