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THBD / CD141 / Thrombomodulin
thrombomodulin
Thrombomodulin is a specific endothelial cell receptor that forms a 1:1 stoichiometric complex with thrombin. This complex is responsible for the conversion of protein C to the activated protein C (protein Ca). Once evolved, protein Ca scissions the activated cofactors of the coagulation mechanism, factor Va and factor VIIIa, and thereby reduces the amount of thrombin generated.
| Gene Name: | thrombomodulin |
| Synonyms: | THBD, BDCA3, CD141 antigen, CD141, AHUS6, Fetomodulin, THPH12, TM, THRM, Thrombomodulin |
| Target Sequences: | NM_000361 NP_000352.1 P07204 |
Publications (2)
1
T cell infiltration on local CpG-B delivery in early-stage melanoma is predominantly related to CLEC9A +<sup> CD141 +<sup> cDC1 and CD14 +<sup> antigen-presenting cell recruitment. Bas D Koster #, Marta López González #, Mari Fcm van den Hout , Annelies W Turksma, Berbel Jr Sluijter, Barbara G Molenkamp, Paul Am van Leeuwen, Saskia Vosslamber, Rik J Scheper, Alfons Jm van den Eertwegh, M Petrousjka van den Tol, Ekaterina J Jordanova , Tanja D de Gruijl. Journal for immunotherapy of cancer. 2021 Mar;;9:e001962. [Full Text Article]
[PubMed:33737341]
[PMC:PMC7978250]
2
Transgenic Expression of Human Thrombomodulin Inhibits HMGB1-Induced Porcine Aortic Endothelial Cell Activation. Anjan K Bongoni, Nikolai Klymiuk, Eckhard Wolf, David Ayares, Robert Rieben, Peter J Cowan. Transplantation. 2016 September;100:1871-9. [Full Text Article]
[PubMed:27077599]
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THBD / CD141 / Thrombomodulin Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
THBD / CD141 / Thrombomodulin Rat anti-Mouse Monoclonal (aa17-517) (461714) Antibody
Mouse
ELISA, Flo, ICC, IHC, IHC-Fr, WB
Unconjugated
100 µg/$896
Sandwich
96-Well Microplate
Human
62.5 - 4000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum, Urine
1 Plate/$699
Sandwich
12 x 8-Well Microstrips
Human
32 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Plasma, Serum
1 Plate/$534
Sandwich
96-Well Strip Plate
Pig
0.781 - 50 ng/ml
Colorimetric - 450nm (TMB)
Plasma
1 Plate/$779
Sandwich
96-Well Strip Plate
Mouse
62.5 - 4000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
Sandwich
96-Well Microplate
Rat
93.75 - 6000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$771
Sandwich
96-Well Strip Plate
Rat
93.75 - 6000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$587
THBD / CD141 / Thrombomodulin Rabbit anti-Human Polyclonal (aa31-169) Antibody
Pig, Human
WB
Unconjugated
100 µl/$299; 200 µl/$336; 500 µl/$462; 1 ml/$525; 2 ml/$677; 5 ml/$1,136
Sandwich
96-Well Strip Plate
Rabbit
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$715
THBD / CD141 / Thrombomodulin Rat anti-Human Monoclonal Antibody
Human
Flo, Func, WB
Unconjugated
100 µg/$862
Cancer Pathology
Cancer
THBD / CD141 / Thrombomodulin Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
ICC, IHC, IHC-P, WB
Unconjugated
100 µl/$485
Sandwich
96-Well Strip Plate
Porcine
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
E. coli
His-T7
18.8 kDa
10 µg/$287; 50 µg/$482; 100 µg/$770; 200 µg/$962; 1 mg/$2,094; 500 µg/$1,623; 5 mg/$3,361; 2 mg/$2,284
THBD / CD141 / Thrombomodulin Mouse anti-Human Monoclonal (aa19-515) Antibody
Human
Flo, IHC
Unconjugated
100 µg/$951
Cancer Pathology
Cancer
THBD / CD141 / Thrombomodulin Mouse anti-Human Recombinant Monoclonal (aa 69-194) (rTHBD/1591) Antibody
Human
ELISA, IHC-P
Unconjugated
100 µg/$525
THBD / CD141 / Thrombomodulin Rat anti-Human Monoclonal (RTM98) Antibody
Human
Flo, WB
Unconjugated
100 µg/$589
THBD / CD141 / Thrombomodulin Goat anti-Mouse Polyclonal (Extracellular Domain) (Biotin) Antibody
Mouse
Flo, WB
Biotin Conjugated
50 µg/$973
THBD / CD141 / Thrombomodulin Mouse anti-Human Monoclonal (THBD/1591) Antibody
Human
ELISA, Flo, IF, IHC-P, WB
Unconjugated
20 µg/$371; 100 µg/$574
THBD / CD141 / Thrombomodulin Mouse anti-Human Monoclonal (Azide-free, BSA-free) (THBD/1591) Antibody
Human
ELISA, Flo, IF, IHC-P, WB
Unconjugated, Azide-free, BSA-free
100 µg/$574
THBD / CD141 / Thrombomodulin Mouse anti-Human Monoclonal (aa19-515) (Biotin) Antibody
Human
ELISA
Biotin Conjugated
50 µg/$978
THBD / CD141 / Thrombomodulin Mouse anti-Human Monoclonal (THBD/1782) Antibody
Human
ELISA, Flo, IF, IHC-P
Unconjugated
20 µg/$371; 100 µg/$574
THBD / CD141 / Thrombomodulin Mouse anti-Human Monoclonal (Azide-free, BSA-free) (THBD/1782) Antibody
Human
ELISA, Flo, IF, IHC-P
Unconjugated, Azide-free, BSA-free
100 µg/$574
THBD / CD141 / Thrombomodulin Rabbit anti-Rat Polyclonal Antibody
Rat
ELISA
Unconjugated
100 µl/$412
THBD / CD141 / Thrombomodulin Rabbit anti-Human Polyclonal (aa325-481) (APC, Cy7) Antibody
Human
WB
APC, Cy7 Conjugated
100 µl/$476; 200 µl/$590; 500 µl/$1,069; 1 ml/$1,265; 2 ml/$1,771; 5 ml/$3,319
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