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Registration enables users to use special features of this website, such as past
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| Catalog Number | Size | Price |
|---|---|---|
| LS-B12463-100 | 100 µl (1 mg/ml) | $485 |
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2 of 2
PathPlus™ Polyclonal Rabbit anti‑Human THBD / CD141 / Thrombomodulin Antibody (C‑Terminus, IHC, WB) LS‑B12463
PathPlus™ Polyclonal Rabbit anti‑Human THBD / CD141 / Thrombomodulin Antibody (C‑Terminus, IHC, WB) LS‑B12463
Note: This antibody replaces LS-C185967
Antibody:
THBD / CD141 / Thrombomodulin Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Application:
IHC, IHC-P, ICC, WB
Reactivity:
Human
Format:
Unconjugated, Unmodified
Toll Free North America
(800) 227-6666
(800) 227-6666For Research Use Only
Overview
Antibody:
THBD / CD141 / Thrombomodulin Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Application:
IHC, IHC-P, ICC, WB
Reactivity:
Human
Format:
Unconjugated, Unmodified
Specifications
Description
THBD (Thrombomodulin; CD141) is an endothelial-specific type I membrane receptor that binds thrombin. Binding of THBD to thrombin leads to decreased fibrinogen-to-fibrin conversion and activation of the coagulation cascade. The THBD/thrombin complex catalyzes protein C activation, which increases inhibition of coagulation by inactivating cofactors Va and VIIIa. Mutations in this gene are implicated in inherited thrombophilia and recurrent pregnancy loss.
References: Reprod Biol Endocrinol 2017 15:92
Target
Human THBD / CD141 / Thrombomodulin
Synonyms
THBD | BDCA3 | CD141 antigen | CD141 | AHUS6 | Fetomodulin | THPH12 | TM | THRM | Thrombomodulin
Host
Rabbit
Reactivity
Human
(tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Immunogen
Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human Thrombomodulin. The exact sequence is proprietary.
Epitope
C-Terminus
Specificity
Human CD141 / Thrombomodulin
Applications
- IHC
- IHC - Paraffin (10 - 20 µg/ml)
- ICC (1:100 - 1:1000)
- Western blot (1:500 - 1:3000)
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Presentation
1X PBS, pH 7, 0.025% ProClin™ 300, 20% Glycerol
Storage
Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
About THBD / CD141 / Thrombomodulin
Validation
Human Small Intestine, Vessels: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Small Intestine, Vessels: Formalin-Fixed, Paraffin-Embedded (FFPE)
See More About...
LSBio Ratings
PathPlus™ THBD / CD141 / Thrombomodulin Antibody (C-Terminus) for IHC, ICC, WB/Western LS-B12463 has an LSBio Rating of
Laboratory Validation Score (5)
Learn more about The LSBio Ratings Algorithm
Publications (0)
Customer Reviews (0)
Featured Products
Species:
Human
Applications:
IHC - Paraffin, ELISA
Species:
Mouse
Applications:
IHC, IHC - Frozen, ICC, Western blot, Flow Cytometry, ELISA
Species:
Human, Mouse, Rat
Applications:
IHC, IHC - Paraffin, Western blot
Species:
Human
Applications:
Western blot, Flow Cytometry, Functional Assay
Species:
Mouse
Applications:
Western blot, Flow Cytometry
Species:
Human
Applications:
ELISA
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 11/22/2024
Date Requested: 11/22/2024
