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| Catalog Number | Size | Price |
|---|---|---|
| LS-B16186-0.05 | 0.05 ml | $460 |
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2 of 2
PathPlus™ Monoclonal Mouse anti‑Human PDPN / Podoplanin Antibody (clone D2‑40, IHC) LS‑B16186
PathPlus™ Monoclonal Mouse anti‑Human PDPN / Podoplanin Antibody (clone D2‑40, IHC) LS‑B16186
Note: This antibody replaces LS-C312150
Antibody:
PDPN / Podoplanin Mouse anti-Human Monoclonal (D2-40) Antibody
Application:
IHC-P, IHC-Fr
Reactivity:
Human, Mouse, Rat
Format:
Unconjugated, Unmodified
Other formats:
Toll Free North America
(800) 227-6666
(800) 227-6666For Research Use Only
Overview
Antibody:
PDPN / Podoplanin Mouse anti-Human Monoclonal (D2-40) Antibody
Application:
IHC-P, IHC-Fr
Reactivity:
Human, Mouse, Rat
Format:
Unconjugated, Unmodified
Other formats:
Specifications
Description
PDPN (podoplanin) is mucin-type membrane glycoprotein with expression in a diverse range of tissues and cell types including lung alveolar cells, kidney podocytes, lymphatic endothelial cells, and neural tissues. PDPN is a required protein in the development of the lungs, lymphatic system and the heart, and it separately may play a role in immune response to fungal infections. In immunohistochemistry, PDPN has cytoplasmic and membranous staining in the lymphatic endothelium, breast myoepithelium, podocytes, dendritic cells and mesothelium. It is a sensitive and specific marker for the lymphatic endothelium, and it is used as an endothelial cell marker in determining lymphatic invasion in tumors.
References: Clin Inv. 118 (11): 3725–37, PMID: 18924607; Frontiers in Immunology. 2012. 3: 283. doi:10.3389/fimmu.2012.00283, PMID: 22988448
Target
Human PDPN / Podoplanin
Synonyms
PDPN | AGGRUS | HT1alpha-1 | Glycoprotein 36 | Glycoprotein, 36-KD | gp36 | gp38 | OTS8 | PA2.26 | PA2.26 antigen | Podoplanin | T1A | gp40 | HT1A-1 | HT1alpha-2 | p38 | T1-alpha | T1A-2
Host
Mouse
Reactivity
Human, Mouse, Rat
(tested or 100% immunogen sequence identity)
Clonality
IgG1
Monoclonal
Clone
D2-40
Conjugations
Unconjugated
Purification
Tissue culture supernatant
Modifications
Unmodified.
Also available Unmodified or Ready-to-Use.
Immunogen
Resected tissue from dysgeminoma of the ovary.
Applications
- IHC - Paraffin (1:50)
- IHC - Frozen (1:100 - 1:500)
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Usage
Immunohistochemistry: Paraffin and frozen. Control tissue: Tonsil, Lymph Node, Lymphangioma. Localization: Cytoplasmic.
Presentation
Filter sterilized and diluted in buffer, pH 7.5, BSA, Sodium Azide
Storage
Store at 2°C to 8°C.
Restrictions
For research use only. Intended for use by laboratory professionals.
About PDPN / Podoplanin
Validation
Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Thyroid: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Thyroid: Formalin-Fixed, Paraffin-Embedded (FFPE)
See More About...
LSBio Ratings
PathPlus™ PDPN / Podoplanin Antibody (clone D2-40) for IHC LS-B16186 has an LSBio Rating of
Laboratory Validation Score (5)
Learn more about The LSBio Ratings Algorithm
Publications (0)
Customer Reviews (0)
Featured Products
Species:
Human
Applications:
IHC, IHC - Paraffin, Western blot
Species:
Human
Applications:
IHC - Paraffin, ELISA
Species:
Human, Mouse
Applications:
IHC, IHC - Paraffin, Western blot, ELISA
Species:
Human
Applications:
IHC, IHC - Paraffin, Western blot
Species:
Human
Applications:
IHC, IHC - Paraffin, IHC - Frozen
Species:
Human
Applications:
Immunofluorescence, Western blot, Immunoprecipitation
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 11/22/2024
Date Requested: 11/22/2024
