Human PDPN / Podoplanin

Mouse

Human (tested or 100% immunogen sequence identity)

IgG1 Monoclonal

4D5aE5E6

Unconjugated

Protein G purified

Unmodified

ORF Human podoplanin ectodomain expressed in E. coli.

Recognizes Human Podoplanin (gp36), a 36kD type I cell membrane-associated glycoprotein, with a broad spectrum of distribution, being strongly expressed on the lymphatic endothelium found in lung, placenta and skeletal muscle and to a lesser extent in brain, kidney and liver. Podoplanin is absent on blood endothelium and therefore Is readily able to distinguish between lymphatic vessels and blood vasculature. Although the specific function of this protein is undetermined, Podoplanin is reported to be a reliable indicator of tumor lymphangiogenesis.

• IHC
• IHC - Paraffin
• IHC - Frozen (0.75 - 2 µg/ml)

Immunohistology: This product requires antigen retrieval using heat treatment prior to staining of paraffin sections. Sodium citrate buffer pH 6.0 is recommended for this purpose.

PBS, 0.09% Sodium Azide

Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.

For research use only. Intended for use by laboratory professionals.

This antibody carries the LSBio 100% Guarantee.

Uniprot: Q86YL7 NCBI: NM_006474 NP_006465.3