CD36 (also known as platelet glycoprotein 4) is a multifunctional membrane-bound glycoprotein receptor for a broad range of ligands. It is a scavenger receptor for proteins such as thrombospondin, collagen, fibronectin, and amyloid-beta as well as oxidized phospholipids, apoptotic cells, and microbial pathogens, acting to internalize receptor-ligand complexes. It is implicated in platelet disorders, atherosclerosis, thrombosis, and Alzheimer disease. CD36 is found on mononuclear phagocytes, platelets, adipocytes, megakaryocytes, erythroid precursors, myocytes, hepatocytes, endothelial cells, and some epithelia. It has also been reported to be expressed in some diseased tissues such as the brain in Alzheimer disease, leukemias, myxoid liposarcoma, and squamous intraepithelial lesions of the cervix. References: Sci Signal. 2009;2(72):re3. doi: 10.1126/scisignal.272re3; Trans Am Clin Climatol Assoc. 2010;121:206-220. PMID: 20697562; Am J Pathol. 2002;160(1):101-112. PMID: 11786404; Mod Pathol. 1998;11(12):1211-1221. PMID: 9872654; Hum Pathol. 1994;25(1):73-79. PMID: 7508885; Am J Clin Pathol. 1995;103(1):20-26. doi: 10.1093/ajcp/103.1.20;