Monoclonal Mouse anti‑Human RB1 / Retinoblastoma / RB Antibody (clone 1F8, IHC, WB) LS‑C95442
Monoclonal Mouse anti‑Human RB1 / Retinoblastoma / RB Antibody (clone 1F8, IHC, WB) LS‑C95442
Note: This antibody replaces LS-C355317
Antibody:
RB1 / Retinoblastoma / RB Mouse anti-Human Monoclonal (1F8) Antibody
Format:
Unconjugated, Unmodified
Overview
Antibody:
RB1 / Retinoblastoma / RB Mouse anti-Human Monoclonal (1F8) Antibody
Format:
Unconjugated, Unmodified
Specifications
Description
RB antibody LS-C95442 is an unconjugated mouse monoclonal antibody to human RB (RB1 / Retinoblastoma). Validated for IHC, IP and WB.
Target
Human RB1 / Retinoblastoma / RB
Synonyms
RB1 | p105-Rb | Osteosarcoma | PRb | Retinoblastoma | Retinoblastoma 1 | OSRC | RB | Pp110
Reactivity
Human
(tested or 100% immunogen sequence identity)
Clonality
IgG1,k
Monoclonal
Conjugations
Unconjugated
Immunogen
Recombinant human Rb protein.
Specificity
Recognizes human retinoblastoma gene protein. Rb gene, a prototype of tumor suppressor genes has been associated with development and/or progression of bladder cancer as well as sarcoma and small cell lung cancer. Functional Rb gene loss has been reported to occur in bladder cancer and osteosarcoma. A significantly poorer tumor-free survival rate was noted for those patients who had a tumor with an altered Rb protein with or without vascular invasion.
Applications
- IHC
- Western blot (1:50 - 1:100)
- Immunoprecipitation (1:50)
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Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
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Presentation
less than 0.1% Sodium Azide
Storage
Store at 2°C to 8°C. Do not freeze.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About RB1 / Retinoblastoma / RB
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Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 11/22/2024