Target
Mouse LTBR
Synonyms
LTBR | D12S370 | CD18 | LT-BETA-R | Lymphotoxin B receptor | Lymphotoxin-beta receptor | TNFR3 | TNF-R-III | TNF-RIII | TNFCR | TNFRSF3 | TNFR-III | TNFR-RP | TNFR2-RP
Reactivity
Mouse
(tested or 100% immunogen sequence identity)
Modifications
Low Endotoxin.
Also available
Unmodified.
Immunogen
Recombinant extracellular domain of LT beta R.
Specificity
Recognizes murine lymphotoxin-beta receptor (LT beta R), a member of the tumor necrosis factor family. LT beta R is primarily expressed on stromal cells and fibroblasts and at lower levels on myeloid cell lines. Clone 5G11b specifically recognizes surface expressed LT beta R. The clone is reported to be agonistic with respect to NF Kappa B activation, MIP-2 induction and IL-6 release. This product is routinely tested on WEH1 cells.