Target
Human ITGAM / CD11b
Synonyms
ITGAM | Antigen CD11b (p170) | CD11B | CD11b antigen | CR3A | Integrin alpha-M | MAC-1 | MO1A | Neutrophil adherence receptor | MAC1A | SLEB6 | CR-3 alpha chain
Reactivity
Human
(tested or 100% immunogen sequence identity)
Clonality
IgG1
Monoclonal
Conjugations
R. Phycoerythrin.
Also available
Unconjugated or conjugated with
FITC.
Purification
Protein G purified
Immunogen
Rheumatoid synovial cells and human monocytes.
Specificity
Recognizes the human CD11b cell surface antigen, also known as the alphaM integrin. CD11b forms a heterodimer with CD18 and is expressed by circulating monocytes, granulocytes and also by dendritic reticulum cells in lymphoid tissue. Expression is increased on activated granulocytes. The CD11b molecule is the receptor for C3bi, fibrinogen and clotting factor X.
Applications
- Flow Cytometry (1:1)
- Applications tested for the base form of this product only
Usage
The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested. Flow Cytometry: Use 10 ul of the suggested working dilution to label 100 ul of whole blood or 10^6 cells in 100 ul. Method sheets are available on request.
Presentation
PBS, 0.09% Sodium Azide, 5% Sucrose, 1% BSA
Reconstitution
Reconstitute with distilled water.
Storage
Store at 4°C. Do not freeze. Store undiluted. Protect from light. Microcentrifugation recommended if solution contains precipitate.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee