Products
Research Areas
COVID-19
Resources
Login
Quick Order
Cart Cart lightblue
Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order
Contact Us

Locations


Orders Processing,
Shipping & Receiving,
Warehouse

2 Shaker Rd Suites
B001/B101
Shirley, MA 01464


Production Lab

Floor 6, Suite 620
20700 44th Avenue W
Lynnwood, WA 98036

Telephone Numbers



Tel: +1 (800) 227-6666


Contact Us



Additional Contact Details

Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order

ITGAM / CD11b

integrin, alpha M (complement component 3 receptor 3 subunit)

Integrin alpha-M/beta-2 is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles. It is identical with CR-3, the receptor for the iC3b fragment of the third complement component. It probably recognizes the R-G-D peptide in C3b. Integrin alpha-M/beta-2 is also a receptor for fibrinogen, factor X and ICAM1. It recognizes P1 and P2 peptides of fibrinogen gamma chain.

Gene Name: integrin, alpha M (complement component 3 receptor 3 subunit)
Family/Subfamily: Integrin , not assigned-Integrin
Synonyms: ITGAM, Antigen CD11b (p170), CD11B, CD11b antigen, CR3A, Integrin alpha-M, MAC-1, MO1A, Neutrophil adherence receptor, MAC1A, SLEB6, CR-3 alpha chain
Target Sequences: NM_000632 NP_000623.2 P11215

Publications (21)

1
Dissection of the hyperadhesive phenotype of airway eosinophils in asthma. Barthel SR, Jarjour NN, Mosher DF, Johansson MW. American journal of respiratory cell and molecular biology. 2006 35:378-86. [PubMed:16601240] [PMC:PMC1550734] Related Antibodies: LS-C40808.
2
Functional heterogeneity and differential priming of circulating neutrophils in human experimental endotoxemia. Pillay J, Ramakers BP, Kamp VM, Loi AL, Lam SW, Hietbrink F, Leenen LP, Tool AT, Pickkers P, Koenderman L. Journal of leukocyte biology. 2010 88:211-20. [PubMed:20400675] Related Antibodies: LS-C40808.
3
Basophils and the T helper 2 environment can promote the development of lupus nephritis. Charles N, Hardwick D, Daugas E, Illei GG, Rivera J. Nature medicine. 2010 16:701-7. [PubMed:20512127] [PMC:PMC2909583] Related Antibodies: LS-C40807.
4
Terminal differentiation of chronic myelogenous leukemia cells is induced by targeting of the MUC1-C oncoprotein. Yin L, Ahmad R, Kosugi M, Kawano T, Avigan D, Stone R, Kharbanda S, Kufe D. Cancer biology & therapy. 2010 10:483-91. (IHC; Human) [PubMed:20592495] [PMC:PMC3034602]
5
Gelatinase contributes to the pathogenesis of endocarditis caused by Enterococcus faecalis. Thurlow LR, Thomas VC, Narayanan S, Olson S, Fleming SD, Hancock LE. Infection and immunity. 2010 78:4936-43. [PubMed:20713628] [PMC:PMC2976315] Related Antibodies: LS-C40807.
6
Toll-like receptor 4 mediates the response of epithelial and stromal cells to lipopolysaccharide in the endometrium. Sheldon IM, Roberts MH. PloS one. 2010 5:e12906. (IHC; Mouse) [PubMed:20877575] [PMC:PMC2943929]
7
The Vi capsular polysaccharide prevents complement receptor 3-mediated clearance of Salmonella enterica serotype Typhi. Wilson RP, Winter SE, Spees AM, Winter MG, Nishimori JH, Sanchez JF, Nuccio SP, Crawford RW, Tkel, Bumler AJ. Infection and immunity. 2011 79:830-7. [PubMed:21098104] [PMC:PMC3028862] Related Antibodies: LS-C40808.
8
Altered hippocampal synaptic transmission in transgenic mice with astrocyte-targeted enhanced CCL2 expression. Nelson TE, Hao C, Manos J, Ransohoff RM, Gruol DL. Brain, behavior, and immunity. 2011 S106-19. (WB; Mouse) [PubMed:21356306]
9
MUC1-C oncoprotein suppresses reactive oxygen species-induced terminal differentiation of acute myelogenous leukemia cells. Yin L, Wu Z, Avigan D, Rosenblatt J, Stone R, Kharbanda S, Kufe D. Blood. 2011 117:4863-70. [PubMed:21422470] [PMC:PMC3100696]
10
Hax1 regulates neutrophil adhesion and motility through RhoA. Cavnar PJ, Berthier E, Beebe DJ, Huttenlocher A. The Journal of cell biology. 2011 193:465-73. [PubMed:21518791] [PMC:PMC3087009] Related Antibodies: LS-C40808.
11
Infection of dendritic cells with herpes simplex virus type 1 induces rapid degradation of CYTIP, thereby modulating adhesion and migration. Theodoridis AA, Eich C, Figdor CG, Steinkasserer A. Blood. 2011 118:107-15. [PubMed:21562043] Related Antibodies: LS-C40808.
12
Neuroadaptive changes in cerebellar neurons induced by chronic exposure to IL-6. Gruol DL, Puro A, Hao C, Blakely P, Janneke E, Vo K. Journal of neuroimmunology. 2011 239:28-36. (WB; Rat) [PubMed:21890220] [PMC:PMC3428218]
13
Hypoxia-inducible factor 1 is a master regulator of breast cancer metastatic niche formation. Wong CC, Gilkes DM, Zhang H, Chen J, Wei H, Chaturvedi P, Fraley SI, Wong CM, Khoo US, Ng IO, Wirtz D, Semenza GL. Proceedings of the National Academy of Sciences of the United States of America. 2011 108:16369-74. (IHC, WB, IHC-P; Mouse, Human) [PubMed:21911388] [PMC:PMC3182724]
14
Human eosinophils express RAGE, produce RAGE ligands, exhibit PKC-delta phosphorylation and enhanced viability in response to the RAGE ligand, S100B. Curran CS, Bertics PJ. International immunology. 2011 23:713-28. [PubMed:22025532] [PMC:PMC3226529] Related Antibodies: LS-C40808.
15
Inhibitors of hypoxia-inducible factor 1 block breast cancer metastatic niche formation and lung metastasis. Wong CC, Zhang H, Gilkes DM, Chen J, Wei H, Chaturvedi P, Hubbi ME, Semenza GL. Journal of molecular medicine (Berlin, Germany). 2012 90:803-15. (IHC; Mouse) [PubMed:22231744] [PMC:PMC3437551]
16
Altered synaptic transmission in the hippocampus of transgenic mice with enhanced central nervous systems expression of interleukin-6. Nelson TE, Olde Engberink A, Hernandez R, Puro A, Huitron-Resendiz S, Hao C, De Graan PN, Gruol DL. Brain, behavior, and immunity. 2012 26:959-71. (WB; Mouse) [PubMed:22609298] [PMC:PMC3427030]
17
Effect of molecular size and modification pattern on the internalization of water soluble -(1 3)-(1 4)-glucan by primary murine macrophages. Zhang M, Kim JA. The international journal of biochemistry & cell biology. 2012 44:914-27. (ICC; Mouse) [PubMed:22679629]
18
Human suppressive neutrophils CD16bright/CD62Ldim exhibit decreased adhesion. Kamp VM, Pillay J, Lammers JW, Pickkers P, Ulfman LH, Koenderman L. Journal of leukocyte biology. 2012 92:1011-20. [PubMed:22927481] Related Antibodies: LS-C40808.
19
Synaptic plasticity in the hippocampus shows resistance to acute ethanol exposure in transgenic mice with astrocyte-targeted enhanced CCL2 expression. Bray JG, Reyes KC, Roberts AJ, Ransohoff RM, Gruol DL. Neuropharmacology. 2013 67:115-25. (WB; Mouse) [PubMed:23164616] [PMC:PMC3595200]
20
VEGFR1-positive macrophages facilitate liver repair and sinusoidal reconstruction after hepatic ischemia/reperfusion injury. Ohkubo H, Ito Y, Minamino T, Eshima K, Kojo K, Okizaki S, Hirata M, Shibuya M, Watanabe M, Majima M. PloS one. 2014 9:e105533. (WB, Flo; Mouse) [Full Text Article] [PubMed:25162491] [PMC:PMC4146544]
21
Frontline Science: Microbiota reconstitution restores intestinal integrity after cisplatin therapy. Perales-Puchalt A, Perez-Sanz J, Payne KK, Svoronos N, Allegrezza MJ, Chaurio RA, Anadon C, Calmette J, Biswas S, Mine JA, Costich TL, Nickels L, Wickramasinghe J, Rutkowski MR, Conejo-Garcia JR. Journal of leukocyte biology. 2018 May;103:799-805. [Full Text Article] [PubMed:29537705] [PMC:PMC6004318] Related Antibodies: LS-C141892.
more

☰ Filters
Antibodies (282)
Proteins (14)
ELISA Kits (6)
Over-Expression Cell Culture Supernatant (1)
Over-Expression Lysate (3)
Primary (282)
Recombinant (10)
Sandwich (6)
ITGAM / CD11b (302)
Human (173)
Mouse (110)
Rat (59)
Baboon (4)
Bovine (4)
Cat (1)
Chimpanzee (3)
Cynomolgus (3)
Dog (2)
Goat (2)
Monkey (8)
Mustelid (1)
Non-Human Primate (4)
Non-Human Primates (10)
Pig (2)
Rabbit (13)
Rhesus monkey (2)
Sheep (1)
IHC (75)
IHC-Fr (48)
IHC-P (13)
WB (88)
Flo (183)
Block (4)
DB (1)
ELISA (18)
Func (25)
ICC (10)
IF (26)
IP (67)
Neut (1)
Peptide-ELISA (3)
Purif (1)
rabbit (92)
mouse (107)
goat (1)
chicken (1)
mouse-balb/c (1)
rat (80)
Product Group
IHCPlus (1)
PathPlus Neuro (1)
IgG (21)
IgG,k (1)
IgG1 (61)
IgG1,k (17)
IgG2a (34)
IgG2b (46)
IgG2b,k (26)
monoclonal mc (187)
polyclonal pc (92)
recombinant monoclonal rmc (3)
107 (1)
198 (1)
3A10H5 (1)
3A33 (10)
4E10 (1)
5C6 (5)
Bear-1 (1)
BEAR-1 (1)
CA16.3E10 (1)
CBRM1/5 (6)
CC126 (2)
ED7 (1)
ED8 (3)
F6.2 (3)
ICR44 (6)
ICRF44 (28)
ITGAM/271 (2)
L1 (1)
M1/70 (46)
M1/70.15 (11)
mCD11b (1)
MEM-170 (2)
MEM-174 (10)
OTI12C10 (2)
OTI2D11 (2)
OX-42 (6)
X-5 (2)
96-Well Microplate (1)
96-Well Strip Plate (5)
AF488 Conjugated (4)
AF647 Conjugated (3)
APC (9)
APC Conjugated (18)
Azide-free (9)
Biotin Conjugated (30)
BSA-free (2)
Carrier-free (2)
Cy3 Conjugated (7)
Cy5 Conjugated (5)
Cy5.5 (3)
Cy5.5 Conjugated (3)
Cy7 Conjugated (14)
DY488 Conjugated (1)
DY550 Conjugated (1)
FITC Conjugated (42)
HRP Conjugated (15)
Low Endotoxin (10)
PE (11)
PE Conjugated (28)
PerCP Conjugated (6)
RPE Conjugated (6)
SPRD Conjugated (3)
Supernatant (1)
Unconjugated (96)
aa301-451 (16)
aa870-1004 (10)
aa248-430 (8)
aa31-160 (8)
aa598-700 (8)
aa808-931 (8)
aa253-282 (7)
Internal (2)
aa630-1104 (2)
Integrin a-M (1)
aa17-382 (1)
aa177-192 (1)
aa339-629 (1)
aa623-728 (1)
aa769-818 (1)
aa807-817 (1)
No (299)
Yes (3)
Cell Culture Supernatants (2)
Cell Lysates (1)
Plasma (5)
Serum (5)
Tissue Homogenates (4)
6His, C-terminus (1)
GST, N-terminus (1)
His (6)
His, N-Terminal (2)
His-GST (1)
Myc-DDK (Flag) (3)
Human (8)
Mouse (2)
Rat (3)
293T Cells (1)
E. coli (7)
HEK 293 Cells (4)
Human (1)
Wheat Germ Extract (1)
Supernatant (1)
Low endotoxin level (1)
ITGAM / CD11b Antibody - Anti-CD11b antibody IHC of mouse spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Select
Neuroscience
ITGAM / CD11b Rat anti-Mouse Monoclonal (M1/70.15) Antibody
Rabbit, Mouse, Human
Flo, IF, IHC, IHC-Fr, IHC-P, IP
Unconjugated
0.05 mg/$460
ITGAM / CD11b Antibody - Human peripheral blood granulocytes stained with purified ICRF44, followed by anti-mouse IgGs FITC
Select
ITGAM / CD11b Mouse anti-Human Monoclonal (ICRF44) Antibody
Pig, Human, Monkey, Baboon
Flo, IHC, IHC-Fr
Unconjugated
100 µg/$243
ITGAM / CD11b Antibody - CD11b Antibody - Microglia Marker - IHC of CD11b in human renal cancer using DAB with hematoxylin counterstain.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
ITGAM / CD11b Rabbit anti-Mouse Polyclonal (Internal) Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
0.1 ml/$386
Select
ITGAM / CD11b Rat anti-Mouse Monoclonal (Azide-free) (M1/70.15) Antibody
Mouse, Human
Block, DB, Flo, Func, IHC, IHC-P, IP, WB
Unconjugated, Azide-free
1 mg/$618
ITGAM / CD11b Antibody - CD11b antibody IHC-paraffin: Human Tonsil Tissue.
Select
ITGAM / CD11b Rabbit anti-Human Polyclonal (aa17-382) Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
Select
ITGAM / CD11b Mouse anti-Rat Monoclonal (OX-42) Antibody
Rat
IHC, IHC-Fr
Unconjugated
1000 µg/$783
ITGAM / CD11b Antibody - Western blot of recombinant ITGAM / CD11b. This image was taken for the base form of this product. Alternate forms, such as conjugated, azide-free, or ready-to-use, have not been tested.
Select
ITGAM / CD11b Rabbit anti-Mouse Polyclonal (aa248-430) Antibody
Mouse
WB
Unconjugated
100 µl/$306; 200 µl/$347; 500 µl/$484; 1 ml/$553; 2 ml/$737; 5 ml/$1,206
ITGAM / CD11b Antibody
Select
ITGAM / CD11b Rat anti-Mouse Monoclonal (Cy5.5, PerCP) (M1/70) Antibody
Mouse, Human
Flo
Cy5.5, PerCP Conjugated
50 Tests/$227; 100 Tests/$239; 200 Tests/$254
Select
ITGAM / CD11b Mouse anti-Bovine Monoclonal (FITC) Antibody
Goat, Sheep, Bovine
Flo
FITC Conjugated
100 µg/$973
Select
ITGAM / CD11b Rat anti-Mouse Monoclonal (M1/70.15) Antibody
Rabbit, Mouse, Human
Flo, Func, IHC, IHC-Fr, IP
Unconjugated
500 µg/$968
Select
ITGAM / CD11b Mouse anti-Dog Monoclonal Antibody
Goat, Dog, Bovine, Pig, Cat, Mustelid
Flo, IHC, IHC-Fr, IP
Unconjugated
2 ml/$862
ITGAM / CD11b ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
31.25 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$798
ITGAM / CD11b ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum, Tissue Homogenates
1 Plate/$669
ITGAM / CD11b ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$669
ITGAM / CD11b ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rat
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Tissue Homogenates
1 Plate/$750
ITGAM / CD11b Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
127.18 kDa
20 µg/$215
ITGAM / CD11b Protein - Recombinant Integrin Alpha M By SDS-PAGE
Select
E. coli
His
21.4 kDa
10 µg/$281; 50 µg/$442; 100 µg/$705; 200 µg/$882; 1 mg/$1,989; 500 µg/$1,529; 5 mg/$3,081; 2 mg/$2,176
ITGAM / CD11b ELISA Kit
Select
Sandwich
96-Well Microplate
Human
2.5 - 600 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$610
ITGAM / CD11b Antibody - CD11b antibody immunohistochemistry of formalin-fixed and paraffin-embedded human hepatocarcinoma followed by peroxidase-conjugated secondary antibody and DAB staining.
Select
ITGAM / CD11b Rabbit anti-Human Polyclonal (aa253-282) Antibody
Human
Flo, IHC, IHC-P, WB
Unconjugated
400 µl/$393
Select
ITGAM / CD11b Mouse anti-Rat Monoclonal (Low Endotoxin) (OX-42) Antibody
Rat
Flo, IF, IHC-Fr, IP
Unconjugated, Low Endotoxin
0.5 mg/$712
ITGAM / CD11b Antibody - SDS-PAGE Analysis of Purified, BSA-Free CD11b Antibody (clone M1/70). Confirmation of Integrity and Purity of the Antibody.
Select
ITGAM / CD11b Rat anti-Mouse Monoclonal (M1/70) Antibody
Rabbit, Mouse, Human, Baboon, Chimpanzee, Cynomolgus, Rhesus monkey
Block, ELISA, Flo, Func, IF, IHC, IHC-Fr, IP
Unconjugated
20 µg/$371; 100 µg/$574
Select
ITGAM / CD11b Chicken anti-Human Polyclonal Antibody
Human
IHC
Unconjugated
1000 µl/$666
ITGAM / CD11b Antibody - PMA activated human granulocytes stained with CBRM1/5 FITC
Select
ITGAM / CD11b Mouse anti-Human Monoclonal (CBRM1/5) Antibody
Human
Flo, IP
Unconjugated
100 µg/$283
Select
ITGAM / CD11b Mouse anti-Human Monoclonal Antibody
Human, Monkey, Baboon, Cynomolgus
Flo, IHC, IHC-Fr, IP
Unconjugated
100 µg/$597; 200 µg/$786
Select
ITGAM / CD11b Mouse anti-Human Monoclonal (ICRF44) Antibody
Human
Flo, IHC, IHC-Fr, IP
Unconjugated
0.1 mg/$385
Viewing 1-25 of 302 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).