Human ITGAM / CD11b

Mouse

Human (tested or 100% immunogen sequence identity)

Cat

IgG1 Monoclonal

ICRF44

Unconjugated. Also available conjugated with RPE, FITC.

Protein G purified

Unmodified

Rheumatoid synovial cells and human monocytes.

Recognizes the human CD11b cell surface glycoprotein, a 165kD molecule also known as the alphaM integrin, MAC-1 and CR3. This molecule is expressed as a heterodimer in association with the beta 2 integrin, and is found upon monocytes, granulocytes, NK cells and some peripheral blood lymphocytes. Blocks some functions of CD11b, although full definition is still to be completed.

• IHC
• IHC - Frozen (1:100 - 1:1000)
• Immunoprecipitation
• Flow Cytometry (1:10 - 1:100)

Flow Cytometry: Use 10 ul of the suggested working dilution to label 10^6 cells or 100 ul whole blood. The epitope recognized by this antibody is reported to be sensitive to formaldehyde fixation and tissue processing. The use of acetone fixation for frozen sections is recommended.

PBS, 0.09% Sodium Azide

Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.

For research use only. Intended for use by laboratory professionals.

This antibody carries the LSBio 100% Guarantee.

Uniprot: P11215 NCBI: NM_000632 NP_000623.2