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| Catalog Number | Size | Price |
|---|---|---|
| LS-B15749-50 | 50 µg | $460 |
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IHC‑plus™ Polyclonal Rabbit anti‑Human FKBP38 / FKBP8 Antibody (IHC, WB) LS‑B15749
IHC‑plus™ Polyclonal Rabbit anti‑Human FKBP38 / FKBP8 Antibody (IHC, WB) LS‑B15749
Note: This antibody replaces LS-C500782
Toll Free North America
(800) 227-6666
(800) 227-6666For Research Use Only
Overview
Specifications
Description
FKBP8 antibody LS-B15749 is an unconjugated rabbit polyclonal antibody to FKBP8 (FKBP38) from human. It is reactive with human and mouse. Validated for ELISA, IHC and WB. Tested on 20 paraffin-embedded human tissues.
Target
Human FKBP38 / FKBP8
Synonyms
FKBP8 | 38 kDa FKBP | 38 kDa FK506-binding protein | FKBP-8 | FK506-binding protein 8 | FKBP38 | HFKBP38 | FKBP-38 | Rotamase | FK506 binding protein 8, 38kDa | FK506-binding protein 8 (38kD) | FKBPr38 | PPIase FKBP8
Host
Rabbit
Reactivity
Human, Mouse
(tested or 100% immunogen sequence identity)
Clonality
IgG
Polyclonal
Purification
Protein G purified
Modifications
Unmodified
Immunogen
Recombinant Human Peptidyl-prolyl cis-trans isomerase FKBP8 protein (58-190AA)
Specificity
Constitutively inactive PPiase, which becomes active when bound to calmodulin and calcium. Seems to act as a chaperone for BCL2, targets it to the mitochondria and modulates its phosphorylation state. The BCL2/FKBP8/calmodulin/calcium complex probably interferes with the binding of BCL2 to its targets. The active form of FKBP8 may therefore play a role in the regulation of apoptosis.
Applications
- IHC
- IHC - Paraffin (10 µg/ml)
- Western blot (1:500 - 1:5000)
- ELISA
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Presentation
PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol.
Storage
Short term: -20°C; Long term: -80°C; Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
About FKBP38 / FKBP8
Validation
Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE), at a concentration of 10 ug/ml.
Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE), at a concentration of 10 ug/ml.
Human Brain, Cortex: Formalin-Fixed, Paraffin-Embedded (FFPE), at a concentration of 10 ug/ml.
Human Brain, Cortex: Formalin-Fixed, Paraffin-Embedded (FFPE), at a concentration of 10 ug/ml.
See More About...
LSBio Ratings
IHC-plus™ FKBP38 / FKBP8 Antibody for IHC, WB/Western, ELISA LS-B15749 has an LSBio Rating of
Laboratory Validation Score (4)
Learn more about The LSBio Ratings Algorithm
Publications (0)
Customer Reviews (0)
Featured Products
Species:
Human
Applications:
IHC, IHC - Paraffin
Species:
Human, Mouse, Rat
Applications:
IHC, IHC - Paraffin, Immunofluorescence, Western blot, Immunoprecipitation
Species:
Human, Mouse, Rat
Applications:
Immunofluorescence, Western blot, Immunoprecipitation
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 12/26/2024
Date Requested: 12/26/2024
