E2F1

E2F transcription factor 1

E2F-1 (also known as transcription factor E2F-1, Retinoblastoma binding protein 3, RBBP-3, PRB-binding protein E2F-1, PBR3, Retinoblastoma-associated protein 1 and RBAP-1) is a transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3'. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein as well as E2F2 and E2F3 have an additional cyclin binding domain. This protein binds preferentially to retinoblastoma protein pRB in a cell-cycle dependent manner. It can mediate both cell proliferation and p53-dependent/independent apoptosis.

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Products

Antibodies (117)

Proteins (4)

ELISA Kits (3)

Type

Cell-Based (1)

Cell-Based Phosphorylation (1)

Over-Expression Lysate (2)

Primary (117)

Recombinant (2)

Sandwich (1)

Target

E2F1 (124)

Reactivity

Human (120)

Mouse (33)

Rat (16)

Bat (7)

Bovine (1)

Chicken (3)

Chimpanzee (7)

Dog (6)

Gibbon (6)

Guinea pig (7)

Horse (6)

Monkey (6)

Pig (7)

Rabbit (6)

Xenopus (6)

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Application

IHC (29)

IHC-P (9)

WB (102)

Flo (8)

DB (14)

ELISA (54)

ICC (7)

IF (11)

IP (24)

Peptide-ELISA (5)

Host

rabbit (88)

mouse (28)

goat (1)

Product Group

IHCPlus (4)

Isotype

IgG (71)

IgG1 (6)

IgG1,k (3)

IgG2a (7)

IgG2a,k (1)

IgG2b (3)

IgG2b,k (1)

Clonality

monoclonal mc (28)

polyclonal pc (89)

Clone

10D1 2B5 (1)

16G7 (1)

17E2 (1)

18E10 (1)

1C3 (1)

1G10 (1)

2 (1)

2E10 (1)

2F10 (1)

6B5 (1)

8G9 (2)

KH20, KH95 (1)

KH95 (1)

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Format

96-Well Microplate (2)

96-Well Strip Plate (1)

APC Conjugated (8)

Azide-free (6)

Biotin Conjugated (12)

FITC Conjugated (12)

HRP Conjugated (12)

PE Conjugated (8)

Preservative Free (1)

Unconjugated (65)

Epitope

Ser332 (7)

aa342-371 (7)

pHis357 (7)

pSer332 (7)

pSer337 (7)

aa109-138 (6)

pThr433 (6)

C-Terminus (5)

aa107-156 (4)

aa297-346 (4)

aa162-476 (3)

Internal (2)

aa223-332 (2)

aa244-264 (2)

aa300-350 (2)

pSer364 (2)

370-450 aa (1)

Amino Acid: 69-223 (1)

Asp426 (1)

aa183-433 (1)

aa246-260 (1)

aa314-327 (1)

aa332-390 (1)

aa387-437 (1)

aa388-437 (1)

p433 (1)

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Publications

No (124)

Sample Type

Adherent Cell Cultures (2)

Tissue Homogenates (1)

Tag

GST, N-terminus (1)

Myc-DDK (Flag) (3)

Species

Human (3)

Source

293T Cells (1)

HEK 293 Cells (2)

Wheat Germ Extract (1)

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E2F1 Antibody (clone 8G9) LS-C169098

Antibody:

E2F1 Mouse anti-Human Monoclonal (8G9) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, Flo, IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$459

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E2F1 Antibody LS-C137257

Antibody:

E2F1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

100 µl/$332

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IHC-plus™ E2F1 Antibody (Internal) LS-B6744

(4.0) Rating

Antibody:

E2F1 Rabbit anti-Human Polyclonal (Internal) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$565

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IHC-plus™ E2F1 Antibody (phospho-Ser364) LS-B52

(4.0) Rating

Antibody:

E2F1 Rabbit anti-Human Polyclonal (pSer364) Antibody

Reactivity:

Human, Chimpanzee

Applications:

ELISA, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µg/$515

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E2F1 Antibody LS-C393681

Antibody:

E2F1 Mouse anti-Human Monoclonal Antibody

Reactivity:

Human

Applications:

ICC, IP, WB

Format:

Unconjugated

Price:

100 µl/$391

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E2F1 Antibody (clone KH20, KH95) LS-C14959

Antibody:

E2F1 Mouse anti-Human Monoclonal (KH20, KH95) Antibody

Reactivity:

Xenopus, Human

Applications:

IP, WB

Format:

Unconjugated

Price:

200 µg/$832

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E2F1 Antibody (aa107-156) LS-C102852

Antibody:

E2F1 Rabbit anti-Human Polyclonal (aa107-156) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

Select

E2F1 Antibody (aa107-156, HRP) LS-C481936

Antibody:

E2F1 Rabbit anti-Human Polyclonal (aa107-156) (HRP) Antibody

Reactivity:

Chicken, Rat, Rabbit, Mouse, Dog, Guinea pig, Pig, Horse, Bat, Gibbon, Chimpanzee, Human, Monkey

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$469

• Unconjugated
• HRP

• Unconjugated
• HRP

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E2F1 Antibody (aa314-327) LS-C205080

Antibody:

E2F1 Goat anti-Human Polyclonal (aa314-327) Antibody

Reactivity:

Human

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µg/$503

Select

E2F1 Antibody (aa109-138) LS-C321000

Antibody:

E2F1 Rabbit anti-Human Polyclonal (aa109-138) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, IF, WB

Format:

Unconjugated

Price:

200 µl/$734

Select

E2F1 Antibody (aa109-138, Biotin) LS-C256419

Antibody:

E2F1 Rabbit anti-Human Polyclonal (aa109-138) (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, ICC, IF, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

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E2F1 Antibody (aa109-138, FITC) LS-C256420

Antibody:

E2F1 Rabbit anti-Human Polyclonal (aa109-138) (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, ICC, IF, WB

Format:

FITC Conjugated

Price:

200 µl/$952

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E2F1 Antibody (aa109-138, APC) LS-C256418

Antibody:

E2F1 Rabbit anti-Human Polyclonal (aa109-138) (APC) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, ICC, IF, WB

Format:

APC Conjugated

Price:

200 µl/$952

Select

E2F1 Antibody (aa109-138, Azide-free, HRP) LS-C256421

Antibody:

E2F1 Rabbit anti-Human Polyclonal (aa109-138) (Azide-free) (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, ICC, IF, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

Select

E2F1 Antibody (aa109-138, PE) LS-C256422

Antibody:

E2F1 Rabbit anti-Human Polyclonal (aa109-138) (PE) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, ICC, IF, WB

Format:

PE Conjugated

Price:

200 µl/$952

• Unconjugated
• Biotin
• FITC
• APC
• HRP, Azide-free
• PE

• Unconjugated
• Biotin
• FITC
• More...
  • APC
  • HRP, Azide-free
  • PE

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E2F1 Antibody (Amino Acid: 69-223, clone 8G9) LS-C759628

Antibody:

E2F1 Mouse anti-Human Monoclonal (Amino Acid: 69-223) (8G9) Antibody

Reactivity:

Mouse, Human

Applications:

Flo, IHC, WB

Format:

Unconjugated

Price:

100 µg/$503

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IHC-plus™ E2F1 Antibody (Ser332) LS-B9117

(4.0) Rating

Antibody:

E2F1 Rabbit anti-Human Polyclonal (Ser332) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

200 µl/$460

Select

IHC-plus™ E2F1 Antibody (aa342-371) LS-B9118

(4.0) Rating

Antibody:

E2F1 Rabbit anti-Human Polyclonal (aa342-371) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

200 µl/$460

Select

E2F1 Antibody LS-C677745

Antibody:

E2F1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P, IP, WB

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

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Mouse/Human E2F1 (Cell-Based ELISA) ELISA Kit - LS-F1950

Type:

Cell-Based

Format:

96-Well Microplate

Reactivity:

Mouse, Human

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Adherent Cell Cultures

Price:

1 Plate/$534

Select

Human E2F1 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G67141

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

46.7 kDa

Price:

20 µg/$1,107

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E2F1 Antibody (phospho-Thr433) LS-C801129

Antibody:

E2F1 Rabbit anti-Human Polyclonal (pThr433) Antibody

Reactivity:

Mouse, Human

Applications:

IF, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

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E2F1 Antibody (phospho-Ser337) LS-C327254

Antibody:

E2F1 Rabbit anti-Human Polyclonal (pSer337) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

200 µl/$734

Select

E2F1 Antibody (Internal) LS-C153570

Antibody:

E2F1 Rabbit anti-Human Polyclonal (Internal) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

50 µg/$440; 100 µg/$480

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E2F1 Antibody (aa244-264, clone 16G7) LS-C19974

Antibody:

E2F1 Mouse anti-Human Monoclonal (aa244-264) (16G7) Antibody

Reactivity:

Human

Applications:

IF, IP, WB

Format:

Unconjugated

Price:

100 µl/$450

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