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| Catalog Number | Size | Price |
|---|---|---|
| LS-B4846-50 | 50 µl (1.19 mg/ml) | $460 |
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IHC‑plus™ Polyclonal Rabbit anti‑Human DNASE1 / DNase I Antibody (IHC, WB) LS‑B4846
IHC‑plus™ Polyclonal Rabbit anti‑Human DNASE1 / DNase I Antibody (IHC, WB) LS‑B4846
Note: This antibody replaces LS-C109425
Antibody:
DNASE1 / DNase I Rabbit anti-Human Polyclonal Antibody
Application:
IHC, IHC-P, ICC, WB
Reactivity:
Human
Format:
Unconjugated, Unmodified
Toll Free North America
(800) 227-6666
(800) 227-6666For Research Use Only
Overview
Antibody:
DNASE1 / DNase I Rabbit anti-Human Polyclonal Antibody
Application:
IHC, IHC-P, ICC, WB
Reactivity:
Human
Format:
Unconjugated, Unmodified
Specifications
Description
DNase I antibody LS-B4846 is an unconjugated rabbit polyclonal antibody to human DNase I (DNASE1). Validated for ICC, IHC and WB. Tested on 20 paraffin-embedded human tissues. Cited in 3 publications.
Target
Human DNASE1 / DNase I
Synonyms
DNASE1 | Deoxyribonuclease I | Deoxyribonuclease i precursor | DNase I | DNL1 | DRNI | Deoxyribonuclease-1 | DNase I, lysosomal
Host
Rabbit
Reactivity
Human
(tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Immunogen
Recombinant protein corresponding to human DNase I.
Specificity
Human DNase I. Predicted cross-reactivity based on amino acid sequence homology: rabbit (81%), dogs (81%).
Applications
- IHC
- IHC - Paraffin (10 µg/ml)
- ICC (1:100 - 1:1000)
- Western blot (1:500 - 1:3000)
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Presentation
1X PBS, pH 7, 0.025% ProClin™ 300, 20% Glycerol
Storage
Short term: store at 4°C. Long term: aliquot and store at -20°C. Avoid freeze-thaw cycles. Store undiluted.
Restrictions
For research use only. Intended for use by laboratory professionals.
About DNASE1 / DNase I
Validation
Anti-DNase I antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Anti-DNase I antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Anti-DNase I antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Anti-DNase I antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
See More About...
LSBio Ratings
IHC-plus™ DNASE1 / DNase I Antibody for IHC, ICC, WB/Western LS-B4846 has an LSBio Rating of
Publications (4.2)
Laboratory Validation Score (4)
Learn more about The LSBio Ratings Algorithm
Publications (3)
TNFα Amplifies DNaseI Expression in Renal Tubular Cells while IL-1β Promotes Nuclear DNaseI Translocation in an Endonuclease-Inactive Form. Thiyagarajan D, Rekvig OP, Seredkina N. PloS one. 2015 10:e0129485. (IHC, WB; Mouse, Human)
IL-1ß Promotes a New Function of DNase I as a Transcription Factor for the Fas Receptor Gene. Thiyagarajan D, Pedersen HL, Seredkina N, Horvei KD, Arranz L, Sonneveld R, Nijenhuis T, van der Vlag J, Rekvig OP. Frontiers in cell and developmental biology. 2018 February;6:7. (Human)
Lupus nephritis: low urinary DNase I levels reflect loss of renal DNase I and may be utilized as a biomarker of disease progression. Pedersen HL, Horvei KD, Thiyagarajan D, Norby GE, Seredkina N, Moroni G, Eilertsen GØ, Holdaas H, Strøm EH, Bakland G, Meroni PL, Rekvig OP. The journal of pathology Clinical research. 2018 July;4:193-203.
Customer Reviews (0)
Featured Products
Species:
Human, Mouse
Applications:
ICC, Western blot, Immunoprecipitation
Species:
Bovine
Applications:
IHC, Western blot, Immunoprecipitation, ELISA
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 12/27/2024
Date Requested: 12/27/2024
