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| Catalog Number | Size | Price |
|---|---|---|
| LS-C498560-50 | 50 µg | $294 |
| LS-C498560-100 | 100 µg | $360 |
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Polyclonal Rabbit anti‑Human CYP3A4 / Cytochrome P450 3A4 Antibody (IHC, IF) LS‑C498560
Polyclonal Rabbit anti‑Human CYP3A4 / Cytochrome P450 3A4 Antibody (IHC, IF) LS‑C498560
Toll Free North America
(800) 227-6666
(800) 227-6666For Research Use Only
Overview
Specifications
Description
Cytochrome P450 3A4 antibody LS-C498560 is an unconjugated rabbit polyclonal antibody to human Cytochrome P450 3A4 (CYP3A4). Validated for ELISA, IF and IHC.
Target
Human CYP3A4 / Cytochrome P450 3A4
Synonyms
CYP3A4 | Cyp3a3 | CYPIIIA3 | CYPIIIA4 | Cytochrome P450 3A3 | Cytochrome P450 3A4 | CP33 | CP34 | CYP3A | Cytochrome P450 NF-25 | HLP | NF-25 | p450C3 | Cytochrome P450 HLp | Cytochrome P450-PCN1 | Glucocorticoid-inducible P450 | p450-III, steroid inducible | p450PCN1
Host
Rabbit
Reactivity
Human
(tested or 100% immunogen sequence identity)
Clonality
IgG
Polyclonal
Purification
Protein G purified
Modifications
Unmodified
Immunogen
Recombinant Human Cytochrome P450 3A4 protein (259-441AA)
Specificity
Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It performs a variety of oxidation reactions (e.g. caffeine 8-oxidation, omeprazole sulphoxidation, midazolam 1'-hydroxylation and midazolam 4-hydroxylation) of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. Acts as a 1,8-cineole 2-exo-monooxygenase. The enzyme also hydroxylates etoposide (PubMed:11159812). Catalyzes 4-beta-hydroxylation of cholesterol. May catalyze 25-hydroxylation of cholesterol in vitro (PubMed:21576599).
Applications
- IHC
- Immunofluorescence
- ELISA
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Presentation
PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol.
Storage
Short term: -20°C; Long term: -80°C; Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
About CYP3A4 / Cytochrome P450 3A4
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Featured Products
Species:
Human, Rat
Applications:
Western blot
Species:
Human
Applications:
IHC, IHC - Paraffin, Immunofluorescence, Western blot, Flow Cytometry, ELISA
Species:
Human, Mouse, Rat
Applications:
IHC, IHC - Paraffin, Western blot, Flow Cytometry
Species:
Human, Chimpanzee, Orangutan, Gibbon, Bovine, Pig
Applications:
Western blot
Reactivity:
Rat
Range:
1-25 ng/ml
Reactivity:
Mouse
Range:
1.56-100 ng/ml
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 11/7/2024
Date Requested: 11/7/2024
