CYP3A4 / Cytochrome P450 3A4

cytochrome P450, family 3, subfamily A, polypeptide 4

CYP3A4 / Cytochrome P450 3A4 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases that catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by glucocorticoids and some pharmacological agents. This enzyme is involved in the metabolism of approximately half the drugs in use today, including acetaminophen, codeine, cyclosporin A, diazepam and erythromycin. The enzyme also metabolizes some steroids and carcinogens. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. Previously another CYP3A gene, CYP3A3, was thought to exist; however, it is now thought that this sequence represents a transcript variant of CYP3A4. Alternatively spliced transcript variants encoding different isoforms have been identified.

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Antibodies (50)

ELISA Kits (6)

Proteins (6)

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Competitive EIA (1)

Over-Expression Lysate (2)

Primary (50)

Recombinant (4)

Sandwich (5)

Target

CYP3A4 / Cytochrome P450 3A4 (62)

Reactivity

Human (53)

Mouse (14)

Rat (20)

Bovine (6)

Chimpanzee (6)

Gibbon (6)

Orangutan (6)

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IHC-P (7)

WB (41)

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ICC (1)

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rabbit (45)

mouse (4)

goat (1)

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IHCPlus (1)

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IgG (31)

IgG1 (2)

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monoclonal mc (2)

polyclonal pc (48)

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3H8 (2)

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aa344-497 (8)

aa251-300 (4)

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aa1-503 (1)

aa257-268 (1)

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Cell Lysates (2)

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Serum (4)

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293T Cells (1)

E. coli (1)

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Wheat Germ Extract (2)

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IHC-plus™ CYP3A4 / Cytochrome P450 3A4 Antibody LS-B12328

(4.0) Rating

Antibody:

CYP3A4 / Cytochrome P450 3A4 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

Flo, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$460

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CYP3A4 / Cytochrome P450 3A4 Antibody (aa 243-430, clone 3H8) LS-C169171

Antibody:

CYP3A4 / Cytochrome P450 3A4 Mouse anti-Human Monoclonal (aa 243-430) (3H8) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$459

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CYP3A4 / Cytochrome P450 3A4 Antibody (Biotin) LS-C36104

Antibody:

CYP3A4 / Cytochrome P450 3A4 Rabbit anti-Human Polyclonal (Biotin) Antibody

Reactivity:

Rat, Human

Applications:

WB

Format:

Biotin Conjugated

Price:

50 µl/$582

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Human CYP3A4 / Cytochrome P450 3A4 (Sandwich ELISA) ELISA Kit - LS-F8043

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.313 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Tissue Homogenates

Price:

1 Plate/$730

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CYP3A4 / Cytochrome P450 3A4 Antibody (aa251-300, HRP) LS-C454743

Antibody:

CYP3A4 / Cytochrome P450 3A4 Rabbit anti-Human Polyclonal (aa251-300) (HRP) Antibody

Reactivity:

Bovine, Pig, Orangutan, Gibbon, Human, Chimpanzee

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$469

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Human CYP3A4 / Cytochrome P450 3A4 (Sandwich ELISA) ELISA Kit - LS-F32886

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

78 - 5000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

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Human CYP3A4 / Cytochrome P450 3A4 Protein (Recombinant GST) (Full Length) - LS-G28135

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

83.7 kDa

Price:

2 µg/$439

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CYP3A4 / Cytochrome P450 3A4 Antibody (clone 3H8) LS-C759624

Antibody:

CYP3A4 / Cytochrome P450 3A4 Mouse anti-Human Monoclonal (3H8) Antibody

Reactivity:

Human

Applications:

Flo, ICC, IF, IHC, WB

Format:

Unconjugated

Price:

100 µg/$503

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CYP3A4 / Cytochrome P450 3A4 Antibody LS-C664935

Antibody:

CYP3A4 / Cytochrome P450 3A4 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IF, IHC, WB

Format:

Unconjugated

Price:

100 µg/$331

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CYP3A4 / Cytochrome P450 3A4 Antibody LS-C498560

Antibody:

CYP3A4 / Cytochrome P450 3A4 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IF, IHC

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

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Mouse CYP3A4 / Cytochrome P450 3A4 (Sandwich ELISA) ELISA Kit - LS-F7755

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

1.56 - 100 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates, Tissue Homogenates

Price:

1 Plate/$748

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Rat CYP3A4 / Cytochrome P450 3A4 (Sandwich ELISA) ELISA Kit - LS-F27379

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

1 - 25 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$805

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CYP3A4 / Cytochrome P450 3A4 Antibody LS-C804676

Antibody:

CYP3A4 / Cytochrome P450 3A4 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

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CYP3A4 / Cytochrome P450 3A4 Antibody LS-C742615

Antibody:

CYP3A4 / Cytochrome P450 3A4 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

50 µl/$334; 100 µl/$397

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CYP3A4 / Cytochrome P450 3A4 Antibody (60-140 aa, Internal) LS-C383035

Antibody:

CYP3A4 / Cytochrome P450 3A4 Rabbit anti-Human Polyclonal (60-140 aa, Internal) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

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CYP3A4 / Cytochrome P450 3A4 Antibody LS-C415692

Antibody:

CYP3A4 / Cytochrome P450 3A4 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IHC, IHC-P

Format:

Unconjugated

Price:

100 µg/$357

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CYP3A4 / Cytochrome P450 3A4 Antibody LS-C804214

Antibody:

CYP3A4 / Cytochrome P450 3A4 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

IHC, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

Select

CYP3A4 / Cytochrome P450 3A4 Antibody LS-C662339

Antibody:

CYP3A4 / Cytochrome P450 3A4 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

10 µg/$318; 100 µg/$470

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CYP3A4 / Cytochrome P450 3A4 Antibody LS-C14782

Antibody:

CYP3A4 / Cytochrome P450 3A4 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

100 µl/$826

Select

CYP3A4 / Cytochrome P450 3A4 Antibody LS-C749224

Antibody:

CYP3A4 / Cytochrome P450 3A4 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, WB

Format:

Unconjugated

Price:

20 µl/$275; 100 µl/$389

Select

CYP3A4 / Cytochrome P450 3A4 Antibody (aa1-503) LS-C121694

Antibody:

CYP3A4 / Cytochrome P450 3A4 Mouse anti-Human Polyclonal (aa1-503) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µg/$705

Select

CYP3A4 / Cytochrome P450 3A4 Antibody LS-C748533

Antibody:

CYP3A4 / Cytochrome P450 3A4 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

20 µl/$275; 100 µl/$389

Select

CYP3A4 / Cytochrome P450 3A4 Antibody (aa257-268) LS-C54695

Antibody:

CYP3A4 / Cytochrome P450 3A4 Goat anti-Human Polyclonal (aa257-268) Antibody

Reactivity:

Human

Applications:

Flo, Peptide-ELISA

Format:

Unconjugated

Price:

100 µg/$503

Select

CYP3A4 / Cytochrome P450 3A4 Antibody LS-C781854

Antibody:

CYP3A4 / Cytochrome P450 3A4 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

IHC-P, WB

Format:

Unconjugated

Price:

100 µg/$575

Select

CYP3A4 / Cytochrome P450 3A4 Antibody LS-C833271

Antibody:

CYP3A4 / Cytochrome P450 3A4 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF

Format:

Unconjugated

Price:

60 µl/$331; 120 µl/$403; 200 µl/$529

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