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CYP3A4 / Cytochrome P450 3A4

cytochrome P450, family 3, subfamily A, polypeptide 4

CYP3A4 / Cytochrome P450 3A4 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases that catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by glucocorticoids and some pharmacological agents. This enzyme is involved in the metabolism of approximately half the drugs in use today, including acetaminophen, codeine, cyclosporin A, diazepam and erythromycin. The enzyme also metabolizes some steroids and carcinogens. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. Previously another CYP3A gene, CYP3A3, was thought to exist; however, it is now thought that this sequence represents a transcript variant of CYP3A4. Alternatively spliced transcript variants encoding different isoforms have been identified.

Gene Name: cytochrome P450, family 3, subfamily A, polypeptide 4
Family/Subfamily: Cytochrome P450 , not assigned-Cytochrome P450
Synonyms: CYP3A4, Cyp3a3, CYPIIIA3, CYPIIIA4, Cytochrome P450 3A3, Cytochrome P450 3A4, CP33, CP34, CYP3A, Cytochrome P450 NF-25, HLP, NF-25, p450C3, Cytochrome P450 HLp, Cytochrome P450-PCN1, Glucocorticoid-inducible P450, p450-III, steroid inducible, p450PCN1
Target Sequences: D00003 BAA00001.1 P08684

☰ Filters
Antibodies (50)
ELISA Kits (6)
Proteins (6)
Competitive EIA (1)
Over-Expression Lysate (2)
Primary (50)
Recombinant (4)
Sandwich (5)
CYP3A4 / Cytochrome P450 3A4 (62)
Human (53)
Mouse (14)
Rat (20)
Bovine (6)
Chimpanzee (6)
Gibbon (6)
Orangutan (6)
Pig (14)
IHC (14)
IHC-P (7)
WB (41)
Flo (4)
ELISA (9)
ICC (1)
IF (7)
Peptide-ELISA (3)
rabbit (45)
mouse (4)
goat (1)
Product Group
IHCPlus (1)
IgG (31)
IgG1 (2)
monoclonal mc (2)
polyclonal pc (48)
3H8 (2)
96-Well Strip Plate (6)
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APC Conjugated (2)
Biotin Conjugated (6)
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PE Conjugated (2)
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aa344-497 (8)
aa251-300 (4)
aa395-444 (4)
60-140 aa, Internal (1)
Internal (1)
aa 243-430 (1)
aa1-503 (1)
aa257-268 (1)
No (62)
Cell Culture Supernatants (1)
Cell Lysates (2)
Plasma (4)
Serum (4)
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GST (1)
GST, N-terminus (1)
His-T7 (1)
Myc-DDK (Flag) (3)
Human (5)
293T Cells (1)
E. coli (1)
HEK 293 Cells (2)
Wheat Germ Extract (2)
Purified (1)
CYP3A4 / Cytochrome P450 3A4 Antibody - Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE)
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CYP3A4 / Cytochrome P450 3A4 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
Flo, IHC, IHC-P, WB
Unconjugated
50 µl/$460
CYP3A4 / Cytochrome P450 3A4 Antibody - IHC of paraffin-embedded liver cancer tissues using CYP3A4 mouse monoclonal antibody with DAB staining.
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CYP3A4 / Cytochrome P450 3A4 Mouse anti-Human Monoclonal (aa 243-430) (3H8) Antibody
Human
ELISA, Flo, IF, IHC, IHC-P, WB
Unconjugated
100 µl/$459
CYP3A4 / Cytochrome P450 3A4 Antibody - Western blot of cytochrome P450 (3A4 isoforms) on rat liver extract. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CYP3A4 / Cytochrome P450 3A4 Rabbit anti-Human Polyclonal (Biotin) Antibody
Rat, Human
WB
Biotin Conjugated
50 µl/$582
CYP3A4 / Cytochrome P450 3A4 ELISA Kit
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Sandwich
96-Well Strip Plate
Human
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Tissue Homogenates
1 Plate/$730
CYP3A4 / Cytochrome P450 3A4 Antibody - CYP3A4 antibody Western blot of Fetal Kidney lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CYP3A4 / Cytochrome P450 3A4 Rabbit anti-Human Polyclonal (aa251-300) (HRP) Antibody
Bovine, Pig, Orangutan, Gibbon, Human, Chimpanzee
WB
HRP Conjugated
100 µl/$469
CYP3A4 / Cytochrome P450 3A4 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
78 - 5000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
CYP3A4 / Cytochrome P450 3A4 Protein - 12.5% SDS-PAGE of human CYP3A4 stained with Coomassie Blue
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Wheat Germ Extract
GST
83.7 kDa
2 µg/$439
CYP3A4 / Cytochrome P450 3A4 Antibody - CYP3A4 Antibody in Immunohistochemistry (IHC)
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CYP3A4 / Cytochrome P450 3A4 Mouse anti-Human Monoclonal (3H8) Antibody
Human
Flo, ICC, IF, IHC, WB
Unconjugated
100 µg/$503
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CYP3A4 / Cytochrome P450 3A4 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, WB
Unconjugated
100 µg/$331
CYP3A4 / Cytochrome P450 3A4 Antibody - Immunohistochemistry of paraffin-embedded human small intestine tissue using CYP3A4 Antibody at dilution of 1:100
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CYP3A4 / Cytochrome P450 3A4 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC
Unconjugated
50 µg/$294; 100 µg/$360
CYP3A4 / Cytochrome P450 3A4 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
1.56 - 100 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Tissue Homogenates
1 Plate/$748
CYP3A4 / Cytochrome P450 3A4 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rat
1 - 25 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$805
CYP3A4 / Cytochrome P450 3A4 Antibody - Staining HeLa cells by IF/ICC. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 min at 25°C. The primary antibody was diluted at 1:200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) antibody, diluted at 1/600, was used as secondary antibody.
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CYP3A4 / Cytochrome P450 3A4 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
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CYP3A4 / Cytochrome P450 3A4 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
50 µl/$334; 100 µl/$397
CYP3A4 / Cytochrome P450 3A4 Antibody - Western blot of CYP3A4 antibody
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CYP3A4 / Cytochrome P450 3A4 Rabbit anti-Human Polyclonal (60-140 aa, Internal) Antibody
Human
ELISA, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
CYP3A4 / Cytochrome P450 3A4 Antibody - Immunohistochemistry of paraffin-embedded human brain tissue using Cytochrome P450 3A4 antibody.
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CYP3A4 / Cytochrome P450 3A4 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, IHC-P
Unconjugated
100 µg/$357
CYP3A4 / Cytochrome P450 3A4 Antibody - Western blot analysis of Cytochrome P450 3A4 expression in HEK293 cells. The lane on the left is treated with the antigen-specific peptide.
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CYP3A4 / Cytochrome P450 3A4 Rabbit anti-Human Polyclonal Antibody
Human
IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
CYP3A4 / Cytochrome P450 3A4 Antibody - CYP3A4 was detected in paraffin-embedded sections of human liver cancer tissues using rabbit anti- CYP3A4 Antigen Affinity purified polyclonal antibody
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CYP3A4 / Cytochrome P450 3A4 Rabbit anti-Human Polyclonal Antibody
Human
IHC, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
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CYP3A4 / Cytochrome P450 3A4 Rabbit anti-Human Polyclonal Antibody
Human
IHC, WB
Unconjugated
100 µl/$826
CYP3A4 / Cytochrome P450 3A4 Antibody - Immunofluorescence analysis of HeLa cells using CYP3A4 antibody at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.
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CYP3A4 / Cytochrome P450 3A4 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, WB
Unconjugated
20 µl/$275; 100 µl/$389
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CYP3A4 / Cytochrome P450 3A4 Mouse anti-Human Polyclonal (aa1-503) Antibody
Human
IHC, IHC-P, WB
Unconjugated
50 µg/$705
CYP3A4 / Cytochrome P450 3A4 Antibody - Immunohistochemistry of paraffin-embedded human liver cancer using CYP3A4 antibody at dilution of 1:100 (40x lens).
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CYP3A4 / Cytochrome P450 3A4 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
20 µl/$275; 100 µl/$389
CYP3A4 / Cytochrome P450 3A4 Antibody - Goat Anti-CYP3A4 Antibody Flow cytometric analysis of paraformaldehyde fixed HepG2 cells (blue line), permeabilized with 0.5% Triton. Primary incubation 1hr (10ug/ml) followed by Alexa Fluor 488 secondary antibody (1ug/ml). IgG control: Unimmunized goat IgG (black line) followed by Alexa Fluor 488 secondary antibody.
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CYP3A4 / Cytochrome P450 3A4 Goat anti-Human Polyclonal (aa257-268) Antibody
Human
Flo, Peptide-ELISA
Unconjugated
100 µg/$503
CYP3A4 / Cytochrome P450 3A4 Antibody - Immunofluorescence analysis of HeLa cells using CYP3A4 Polyclonal Antibody at dilution of 1:100 (40x lens).Blue: DAPI for nuclear staining.
Select
CYP3A4 / Cytochrome P450 3A4 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
CYP3A4 / Cytochrome P450 3A4 Antibody - IHC testing of FFPE human liver cancer tissue with CYP3A4 antibody at 1ug/ml. HIER: steam section in pH6 citrate buffer for 20 min.
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CYP3A4 / Cytochrome P450 3A4 Rabbit anti-Human Polyclonal Antibody
Human
IHC-P, WB
Unconjugated
100 µg/$575
Viewing 1-25 of 62 product results



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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).