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| Catalog Number | Size | Price |
|---|---|---|
| LS-C498663-50 | 50 µg | $294 |
| LS-C498663-100 | 100 µg | $360 |
Polyclonal Rabbit anti‑Human CYP3A4 / Cytochrome P450 3A4 Antibody (Biotin) LS‑C498663
Polyclonal Rabbit anti‑Human CYP3A4 / Cytochrome P450 3A4 Antibody (Biotin) LS‑C498663
Antibody:
CYP3A4 / Cytochrome P450 3A4 Rabbit anti-Human Polyclonal (Biotin) Antibody
Application:
ELISA
Reactivity:
Human
Format:
Biotin, Unmodified
Other formats:
Toll Free North America
(800) 227-6666
(800) 227-6666For Research Use Only
Overview
Antibody:
CYP3A4 / Cytochrome P450 3A4 Rabbit anti-Human Polyclonal (Biotin) Antibody
Application:
ELISA
Reactivity:
Human
Format:
Biotin, Unmodified
Other formats:
Specifications
Description
Cytochrome P450 3A4 antibody LS-C498663 is a biotin-conjugated rabbit polyclonal antibody to human Cytochrome P450 3A4 (CYP3A4). Validated for ELISA.
Target
Human CYP3A4 / Cytochrome P450 3A4
Synonyms
CYP3A4 | Cyp3a3 | CYPIIIA3 | CYPIIIA4 | Cytochrome P450 3A3 | Cytochrome P450 3A4 | CP33 | CP34 | CYP3A | Cytochrome P450 NF-25 | HLP | NF-25 | p450C3 | Cytochrome P450 HLp | Cytochrome P450-PCN1 | Glucocorticoid-inducible P450 | p450-III, steroid inducible | p450PCN1
Host
Rabbit
Reactivity
Human
(tested or 100% immunogen sequence identity)
Clonality
IgG
Polyclonal
Conjugations
Purification
Protein G purified
Modifications
Unmodified
Immunogen
Recombinant Human Cytochrome P450 3A4 protein (259-441AA)
Specificity
Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It performs a variety of oxidation reactions (e.g. caffeine 8-oxidation, omeprazole sulphoxidation, midazolam 1'-hydroxylation and midazolam 4-hydroxylation) of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. Acts as a 1,8-cineole 2-exo-monooxygenase. The enzyme also hydroxylates etoposide (PubMed:11159812). Catalyzes 4-beta-hydroxylation of cholesterol. May catalyze 25-hydroxylation of cholesterol in vitro (PubMed:21576599).
Applications
- ELISA
- Applications tested for the base form of this product only
Presentation
PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol.
Storage
Short term: -20°C; Long term: -80°C; Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
About CYP3A4 / Cytochrome P450 3A4
Publications (0)
Customer Reviews (0)
Featured Products
Species:
Human, Rat
Applications:
Western blot
Species:
Human
Applications:
IHC, IHC - Paraffin, Immunofluorescence, Western blot, Flow Cytometry, ELISA
Species:
Human, Mouse, Rat
Applications:
IHC, IHC - Paraffin, Western blot, Flow Cytometry
Species:
Human, Chimpanzee, Orangutan, Gibbon, Bovine, Pig
Applications:
Western blot
Reactivity:
Rat
Range:
1-25 ng/ml
Reactivity:
Mouse
Range:
1.56-100 ng/ml
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 11/7/2024
Date Requested: 11/7/2024
