Target
Human CYLD
Synonyms
CYLD | CDMT | Deubiquitinating enzyme CYLD | CYLDI | EAC | HSPC057 | MFT1 | MFT | SBS | TEM | BRSS | Ubiquitin thiolesterase CYLD | USPL2 | CYLD1 | KIAA0849 | Ubiquitin thioesterase CYLD
Reactivity
Human, Monkey, Mouse, Bovine, Dog, Guinea pig, Hamster, Horse, Rabbit, Chicken
(tested or 100% immunogen sequence identity)
Predicted
Rat (at least 90% immunogen sequence identity)
Immunogen
A synthetic peptide (DKQTQKLLKVPKGS) corresponding to amino acids 32-45 of human CYLD, GenBank no. ref|NP_001035814.1|. Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Orangutan, Gibbon, Monkey, Galago, Marmoset, Mouse, Dog, Bovine, Hamster, Panda, Horse, Rabbit, Guinea pig, Turkey, Zebra finch, Chicken (100%); Rat, Elephant, Platypus (93%); Opossum (86%).
Specificity
The amino acid sequence used has 100% identity in human, mouse, chimpanzee, bovine and feline, and 92% homologous in rat. Human CYLD is a 956 amino acid protein and the approximate theoretical size is 105 kD.