Target
Human CX3CR1
Synonyms
CX3CR1 | Beta chemokine receptor-like 1 | C-X3-C CKR-1 | Chemokine (C-X3-C) receptor 1 | CMKBRL1 | CMK-BRL-1 | CMKDR1 | CMK-BRL1 | CX3C chemokine receptor 1 | Fkn receptor | GPR13 | GPRV28 | Fractalkine receptor | G protein-coupled receptor v28 | G-protein coupled receptor 13 | V28 | Chemokine c-x3-c receptor 1 | G protein-coupled receptor 13
Reactivity
Human
(tested or 100% immunogen sequence identity)
Conjugations
Horseradish Peroxidase.
Also available
Unconjugated or conjugated with
Biotin,
FITC.
Immunogen
Recombinant human CX3C chemokine receptor 1 protein (298-351AA)
Specificity
Receptor for the CX3C chemokine fractalkine (CX3CL1); binds to CX3CL1 and mediates both its adhesive and migratory functions (PubMed:9390561, PubMed:23125415). Acts as coreceptor with CD4 for HIV-1 virus envelope protein (in vitro) (PubMed:9726990). Isoform 2 and isoform 3 seem to be more potent HIV-1 coreceptors than isoform 1 (PubMed:14607932).