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CX3CR1

chemokine (C-X3-C motif) receptor 1

CX3CR1 a Chemokine Receptor is an HIV coreceptor, as well as a leukocyte chemotactic/adhesion receptor for fractalkine, also known as neurotactin. CX3CR1 mediates chemotactic responses to the soluble form of fractalkine in neutrophils and T cells, and cytoadhesion to cells expressing membrane-anchored fractalkine, such as monocytes, T cells, and neutrophils. Cells transfected with CX3CR1 exhibited chemotaxis and transient increases in intracellular calcium concentration when exposed to fractalkine.

Gene Name: chemokine (C-X3-C motif) receptor 1
Family/Subfamily: GPCR , Chemokine
Synonyms: CX3CR1, Beta chemokine receptor-like 1, C-X3-C CKR-1, Chemokine (C-X3-C) receptor 1, CMKBRL1, CMK-BRL-1, CMKDR1, CMK-BRL1, CX3C chemokine receptor 1, Fkn receptor, GPR13, GPRV28, Fractalkine receptor, G protein-coupled receptor v28, G-protein coupled receptor 13, V28, Chemokine c-x3-c receptor 1, G protein-coupled receptor 13
Target Sequences: NM_001337 NP_001328.1 P49238

Publications (2)

1
Up-regulation of CX3CR1 on tonsillar CD8-positive cells in patients with IgA nephropathy. Otaka R, Takahara M, Ueda S, Nagato T, Kishibe K, Nomura K, Katada A, Hayashi T, Harabuchi Y. Human immunology. 2017 78:375-383. (IHC; Human) [Full Text Article] [PubMed:28196748] Related Antibodies: LS-A86.
2
High Glucose Level Disturbs the Resveratrol-Evoked Curtailment of CX3CL1/CX3CR1 Signaling in Human Placental Circulation. Szukiewicz D, Pyzlak M, Szewczyk G, Stangret A, Trojanowski S, Bachanek M, Braksator W, Wejman J. Mediators of inflammation. 2017 2017:9853108. [Full Text Article] [PubMed:28655972] [PMC:PMC5471565]

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CX3CR1 Antibody - Anti-CX3CR1 antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Neuroscience
CX3CR1 Rabbit anti-Human Polyclonal (Extracellular Domain) Antibody
Human
IHC, IHC-P
Unconjugated
50 µg/$440
CX3CR1 Antibody - IHC of human heart tissue using CX3CR1 antibody at 2 ug/ml.
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CX3CR1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, Flo, IF, IHC, WB
Unconjugated
0.1 mg/$460
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CX3CR1 Goat anti-Mouse Polyclonal (N-Terminus) Antibody
Mouse
Flo, WB
Unconjugated
100 µg/$951
CX3CR1 ELISA Kit
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Sandwich
96-Well Strip Plate
Mouse
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Tissue Homogenates
1 Plate/$715
CX3CR1 ELISA Kit
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Sandwich
96-Well Strip Plate
Mouse
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
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CX3CR1 Mouse anti-Human Monoclonal (Extracellular Domain) (PE) Antibody
Human
Flo
PE Conjugated
100 Tests/$894
CX3CR1 Antibody - Immunohistochemistry of CX3CR1 in human spleen cells with CX3CR1 antibody at 10 µg/ml.
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CX3CR1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
0.1 mg/$460
CX3CR1 ELISA Kit
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Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Tissue Homogenates
1 Plate/$798
CX3CR1 ELISA Kit
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Sandwich
96-Well Microplate
Mouse
0.16 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$586
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CX3CR1 Rabbit anti-Human Polyclonal Antibody
ELISA, IHC, WB
Unconjugated
50 µg/$440; 100 µg/$480
CX3CR1 Protein - 12.5% SDS-PAGE of human CX3CR1 stained with Coomassie Blue
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Wheat Germ Extract
GST
64.79 kDa
2 µg/$439
CX3CR1 Antibody - Staining HeLa cells by IF/ICC. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 min at 25°C. The primary antibody was diluted at 1:200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) antibody, diluted at 1/600 was used as secondary antibody.
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CX3CR1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
CX3CR1 Antibody - Detection limit for recombinant GST tagged CX3CR1 is approximately 10 ng/ml as a capture antibody.
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CX3CR1 Mouse anti-Human Monoclonal (2B11) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$423
CX3CR1 Antibody - Western blot analysis of GPR13 expression in MCF7 (A); NS-1 (B); PC12 (C) whole cell lysates.
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CX3CR1 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Mouse, Rat, Human
WB
Unconjugated
100 µl/$299
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CX3CR1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, Flo, IHC, WB
Unconjugated
100 µg/$331
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CX3CR1 Rabbit anti-Human Polyclonal (270-350 aa, C-terminal) Antibody
Human
ELISA, IF, IHC
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
CX3CR1 Antibody - Immunohistochemistry of paraffin-embedded human heart tissue using CX3CR1 Antibody at dilution of 1:100
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CX3CR1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC
Unconjugated
50 µg/$294; 100 µg/$360
CX3CR1 Antibody - Peptide - + Immunohistochemistry analysis of paraffin-embedded human brain tissue, using CX3CR1 antibody.
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CX3CR1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC
Unconjugated
100 µg/$357
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CX3CR1 Rabbit anti-Human Polyclonal (aa291-340) Antibody
Human
IF, IHC, Peptide-ELISA
Unconjugated
50 µl/$334; 100 µl/$397
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CX3CR1 Rabbit anti-Rat Polyclonal (N-Terminus) Antibody
Rat
IHC, IP, WB
Unconjugated
100 µg/$503
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CX3CR1 Rabbit anti-Human Polyclonal Antibody
Human
IHC, IHC-P
Unconjugated
100 µl/$412
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CX3CR1 Rabbit anti-Human Polyclonal (aa39-69) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
CX3CR1 Antibody - Western blot of Fractalkine Receptor antibody
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CX3CR1 Rabbit anti-Human Polyclonal (120-200 aa, Internal) Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
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CX3CR1 Rabbit anti-Human Polyclonal (Biotin) Antibody
Mouse, Rat, Human
IHC, WB
Biotin Conjugated
100 µl/$968
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CX3CR1 Rabbit anti-Human Polyclonal (PE) Antibody
Mouse, Rat, Human
IHC, WB
PE Conjugated
100 µl/$968
Viewing 1-25 of 69 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).