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CX3CR1

chemokine (C-X3-C motif) receptor 1

CX3CR1 a Chemokine Receptor is an HIV coreceptor, as well as a leukocyte chemotactic/adhesion receptor for fractalkine, also known as neurotactin. CX3CR1 mediates chemotactic responses to the soluble form of fractalkine in neutrophils and T cells, and cytoadhesion to cells expressing membrane-anchored fractalkine, such as monocytes, T cells, and neutrophils. Cells transfected with CX3CR1 exhibited chemotaxis and transient increases in intracellular calcium concentration when exposed to fractalkine.

Gene Name: chemokine (C-X3-C motif) receptor 1
Family/Subfamily: GPCR , Chemokine
Synonyms: CX3CR1, Beta chemokine receptor-like 1, C-X3-C CKR-1, Chemokine (C-X3-C) receptor 1, CMKBRL1, CMK-BRL-1, CMKDR1, CMK-BRL1, CX3C chemokine receptor 1, Fkn receptor, GPR13, GPRV28, Fractalkine receptor, G protein-coupled receptor v28, G-protein coupled receptor 13, V28, Chemokine c-x3-c receptor 1, G protein-coupled receptor 13
Target Sequences: NM_001337 NP_001328.1 P49238

Publications (2)

1
Up-regulation of CX3CR1 on tonsillar CD8-positive cells in patients with IgA nephropathy. Otaka R, Takahara M, Ueda S, Nagato T, Kishibe K, Nomura K, Katada A, Hayashi T, Harabuchi Y. Human immunology. 2017 78:375-383. (IHC; Human) [Full Text Article] [PubMed:28196748] Related Antibodies: LS-A86.
2
High Glucose Level Disturbs the Resveratrol-Evoked Curtailment of CX3CL1/CX3CR1 Signaling in Human Placental Circulation. Szukiewicz D, Pyzlak M, Szewczyk G, Stangret A, Trojanowski S, Bachanek M, Braksator W, Wejman J. Mediators of inflammation. 2017 2017:9853108. [Full Text Article] [PubMed:28655972] [PMC:PMC5471565]

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Products
Antibodies (45)
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CX3CR1 (45)
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PE Conjugated (5)
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aa39-69 (6)
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120-200 aa, Internal (1)
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aa34-47 (1)
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CX3CR1 Antibody - Anti-CX3CR1 antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Neuroscience
CX3CR1 Rabbit anti-Human Polyclonal (Extracellular Domain) Antibody
Human
IHC, IHC-P
Unconjugated
50 µg/$440
CX3CR1 Antibody - IHC of human heart tissue using CX3CR1 antibody at 2 ug/ml.
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CX3CR1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, Flo, IF, IHC, WB
Unconjugated
0.1 mg/$460
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CX3CR1 Goat anti-Mouse Polyclonal (N-Terminus) Antibody
Mouse
Flo, WB
Unconjugated
100 µg/$951
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CX3CR1 Mouse anti-Human Monoclonal (Extracellular Domain) (PE) Antibody
Human
Flo
PE Conjugated
100 Tests/$894
CX3CR1 Antibody - Immunohistochemistry of CX3CR1 in human spleen cells with CX3CR1 antibody at 10 µg/ml.
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CX3CR1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
0.1 mg/$460
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CX3CR1 Rabbit anti-Human Polyclonal Antibody
ELISA, IHC, WB
Unconjugated
50 µg/$440; 100 µg/$480
CX3CR1 Antibody - Staining HeLa cells by IF/ICC. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 min at 25°C. The primary antibody was diluted at 1:200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) antibody, diluted at 1/600 was used as secondary antibody.
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CX3CR1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
CX3CR1 Antibody - Detection limit for recombinant GST tagged CX3CR1 is approximately 10 ng/ml as a capture antibody.
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CX3CR1 Mouse anti-Human Monoclonal (2B11) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$423
CX3CR1 Antibody - Western blot analysis of GPR13 expression in MCF7 (A); NS-1 (B); PC12 (C) whole cell lysates.
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CX3CR1 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Mouse, Rat, Human
WB
Unconjugated
100 µl/$299
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CX3CR1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, Flo, IHC, WB
Unconjugated
100 µg/$331
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CX3CR1 Rabbit anti-Human Polyclonal (270-350 aa, C-terminal) Antibody
Human
ELISA, IF, IHC
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
CX3CR1 Antibody - Immunohistochemistry of paraffin-embedded human heart tissue using CX3CR1 Antibody at dilution of 1:100
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CX3CR1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC
Unconjugated
50 µg/$294; 100 µg/$360
CX3CR1 Antibody - Peptide - + Immunohistochemistry analysis of paraffin-embedded human brain tissue, using CX3CR1 antibody.
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CX3CR1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC
Unconjugated
100 µg/$357
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CX3CR1 Rabbit anti-Human Polyclonal (aa291-340) Antibody
Human
IF, IHC, Peptide-ELISA
Unconjugated
50 µl/$334; 100 µl/$397
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CX3CR1 Rabbit anti-Rat Polyclonal (N-Terminus) Antibody
Rat
IHC, IP, WB
Unconjugated
100 µg/$503
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CX3CR1 Rabbit anti-Human Polyclonal Antibody
Human
IHC, IHC-P
Unconjugated
100 µl/$412
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CX3CR1 Rabbit anti-Human Polyclonal (aa39-69) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
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CX3CR1 Rabbit anti-Human Polyclonal (aa39-69) (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
200 µl/$952
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CX3CR1 Rabbit anti-Human Polyclonal (aa39-69) (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$952
CX3CR1 Antibody - Western blot of Fractalkine Receptor antibody
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CX3CR1 Rabbit anti-Human Polyclonal (120-200 aa, Internal) Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
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CX3CR1 Rabbit anti-Human Polyclonal (HRP) Antibody
Mouse, Rat, Human
IHC, WB
HRP Conjugated
100 µl/$968
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CX3CR1 Rabbit anti-Human Polyclonal (Biotin) Antibody
Mouse, Rat, Human
IHC, WB
Biotin Conjugated
100 µl/$968
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CX3CR1 Rabbit anti-Human Polyclonal (FITC) Antibody
Mouse, Rat, Human
IHC, WB
FITC Conjugated
100 µl/$968
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CX3CR1 Rabbit anti-Human Polyclonal (PE) Antibody
Mouse, Rat, Human
IHC, WB
PE Conjugated
100 µl/$968
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CX3CR1 Rabbit anti-Human Polyclonal (N-Terminal) Antibody
Human
IHC-P, WB
Unconjugated
0.1 mg/$455
Viewing 1-25 of 45 product results


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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).