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Catalog Number Size Price
LS-C44996-0.1 0.1 ml (1 mg/ml) $568 
Antibody

Monoclonal Mouse anti‑Human CFB / Complement Factor B Antibody (clone 014III‑33.2.4.3, N‑Terminus, IHC, WB) LS‑C44996

Monoclonal Mouse anti‑Human CFB / Complement Factor B Antibody (clone 014III‑33.2.4.3, N‑Terminus, IHC, WB) LS‑C44996

Antibody:
CFB / Complement Factor B Mouse anti-Human Monoclonal (N-Terminus) (014III-33.2.4.3) Antibody
Application:
IHC, IHC-Fr, WB, Flo, ELISA
Reactivity:
Human
Format:
Unconjugated, Unmodified
Price
Catalog Number
$568
LS-C44996-0.1
Toll Free North America
(800) 227-6666
For Research Use Only

Overview

Antibody:
CFB / Complement Factor B Mouse anti-Human Monoclonal (N-Terminus) (014III-33.2.4.3) Antibody
Application:
IHC, IHC-Fr, WB, Flo, ELISA
Reactivity:
Human
Format:
Unconjugated, Unmodified

Specifications

Description
Complement Factor B antibody LS-C44996 is an unconjugated mouse monoclonal antibody to human Complement Factor B (CFB) (N-Terminus). Validated for ELISA, Flow, IHC and WB.
Target
Human CFB / Complement Factor B
Synonyms
CFB | AHUS4 | B-factor, properdin | C3/C5 convertase | CFAB | C3 proaccelerator | C3 proactivator | Complement factor B | Complement protein Factor B | Glycine-rich beta-glycoprotein | GBG | Factor B | FB | Glycine-rich beta glycoprotein | PBF2 | BF | BFD | FBI12 | H2-Bf | Properdin factor B
Host
Mouse
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG1 Monoclonal
Clone
014III-33.2.4.3
Conjugations
Unconjugated
Purification
Protein A purified
Modifications
Unmodified
Immunogen
Purified human complement factor b.
Epitope
N-Terminus
Specificity
Recognizes the 30kD Ba fragment of 90kD human complement factor B, present in blood serum. C3b associates with complement factor B, inducing conformational change. This enables complement factor D to cleave the N-terminal of complement factor B (the Ba subunit), leaving the 63 kD Bb subunit associated with C3b, forming C3 convertase. Subunit Ba inhibits lymphocyte proliferation. Conversely, subunit Bb is involved in the proliferation of preactivated B lymphocytes. Binds both the Ba fragment and the whole protein so is not suitable for all ELISA applications.
Applications
  • IHC
  • IHC - Frozen
  • Western blot
  • Flow Cytometry
  • ELISA
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Usage
ELISA: LS-C44996 binds both the Ba fragment and the whole protein so is not suitable for all ELISA applications.
Presentation
BBS, 0.1% Sodium Azide
Storage
Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About CFB / Complement Factor B
P00751 NM_001710 NP_001701.2

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Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at:

Technical.Support@LSBio.com

Requested From: United States
Date Requested: 11/24/2024