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CFB / Complement Factor B

complement factor B

CFB / Complement Factor B is complement factor B, a component of the alternative pathway of complement activation. Factor B circulates in the blood as a single chain polypeptide. Upon activation of the alternative pathway, it is cleaved by complement factor D yielding the noncatalytic chain Ba and the catalytic subunit Bb. The active subunit Bb is a serine protease which associates with C3b to form the alternative pathway C3 convertase. Bb is involved in the proliferation of preactivated B lymphocytes, while Ba inhibits their proliferation. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. This cluster includes several genes involved in regulation of the immune reaction. Polymorphisms in this gene are associated with a reduced risk of age-related macular degeneration. The polyadenylation site of this gene is 421 bp from the 5' end of the gene for complement component 2.

Gene Name: complement factor B
Family/Subfamily: Protease , Serine S1
Synonyms: CFB, AHUS4, B-factor, properdin, C3/C5 convertase, CFAB, C3 proaccelerator, C3 proactivator, Complement factor B, Complement protein Factor B, Glycine-rich beta-glycoprotein, GBG, Factor B, FB, Glycine-rich beta glycoprotein, PBF2, BF, BFD, FBI12, H2-Bf, Properdin factor B
Target Sequences: NM_001710 NP_001701.2 P00751

☰ Filters
Antibodies (140)
ELISA Kits (26)
Proteins (19)
Competitive EIA (1)
Custom (3)
Over-Expression Cell Culture Supernatant (1)
Over-Expression Lysate (2)
Primary (140)
Recombinant (16)
Sandwich (22)
CFB / Complement Factor B (185)
Human (93)
Mouse (52)
Rat (53)
Bovine (1)
Chicken (1)
Monkey (1)
Pig (1)
Porcine (1)
Rabbit (1)
Rhesus monkey (1)
IHC (28)
IHC-Fr (4)
IHC-P (11)
WB (132)
Flo (18)
ELISA (38)
Func (1)
ICC (10)
ID (1)
IF (2)
IP (8)
Peptide-ELISA (2)
rabbit (106)
mouse (33)
goat (1)
Product Group
IHCPlus (4)
IgG (35)
IgG1 (14)
IgG1 + IgG2b (1)
IgG2a (6)
IgG2b (2)
monoclonal mc (33)
polyclonal pc (107)
014III-33.2.4.3 (1)
032B-22.1.X (1)
10-09 (1)
96-Well Microplate (3)
96-Well Strip Plate (23)
APC (10)
APC Conjugated (11)
Azide-free (1)
Biotin Conjugated (19)
Cy3 Conjugated (10)
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PE Conjugated (14)
Unconjugated (41)
aa270-388 (18)
aa34-159 (18)
aa35-160 (10)
aa269-382 (8)
aa32-157 (8)
aa474-590 (8)
aa476-592 (8)
aa477-600 (8)
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210-290 aa, Internal (1)
Cleaved-Lys260 (1)
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aa23-761 (1)
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aa26-764 (1)
aa395-422 (1)
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6His, C-terminus (2)
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His-MBP (1)
Myc-DDK (Flag) (3)
Human (11)
Mouse (3)
Rat (4)
293T Cells (1)
E. coli (13)
HEK 293 Cells (3)
Human Cells (1)
Mammalian Cells (1)
Purified (2)
Low endotoxin level (3)
CFB / Complement Factor B Antibody - Anti-CFB / Factor B antibody IHC of human adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:200.
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CFB / Complement Factor B Goat anti-Human Polyclonal Antibody
Human
ID, IHC, IHC-P
Unconjugated
1 ml/$485
CFB / Complement Factor B Antibody - Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CFB / Complement Factor B Rabbit anti-Human Polyclonal (aa23-761) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$460
CFB / Complement Factor B Antibody - Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CFB / Complement Factor B Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA, IHC, IHC-P, WB
HRP Conjugated
50 µg/$294; 100 µg/$360
CFB / Complement Factor B Antibody - Western blot of recombinant CFB / Complement Factor B.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CFB / Complement Factor B Rabbit anti-Mouse Polyclonal (aa474-590) Antibody
Mouse, Rat
WB
Unconjugated
100 µl/$311; 200 µl/$355; 500 µl/$499; 1 ml/$571; 2 ml/$777; 5 ml/$1,261
CFB / Complement Factor B Antibody - Western blot of recombinant CFB / Complement Factor B.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CFB / Complement Factor B Rabbit anti-Mouse Polyclonal (aa474-590) (Biotin) Antibody
Mouse, Rat
WB
Biotin Conjugated
100 µl/$321; 200 µl/$369; 500 µl/$527; 1 ml/$611; 2 ml/$842; 5 ml/$1,387
CFB / Complement Factor B Antibody - Western blot of extracts from K562 cells, treated with etoposide 25 uM 1h, using CFAB Bb (Cleaved-Lys260) Antibody. The lane on the right is treated with the synthesized peptide.
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CFB / Complement Factor B Rabbit anti-Human Polyclonal (aa241-290) Antibody
Mouse, Human
Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
CFB / Complement Factor B Antibody - Western blot of recombinant CFB / Complement Factor B.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CFB / Complement Factor B Rabbit anti-Mouse Polyclonal (aa32-157) Antibody
Mouse
WB
Unconjugated
100 µl/$311; 200 µl/$355; 500 µl/$499; 1 ml/$571
CFB / Complement Factor B Antibody - Immunohistochemistry of paraffin-embedded mouse kidney using CFB antibodyat dilution of 1:200 (40x lens).
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CFB / Complement Factor B Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
20 µl/$275; 100 µl/$389
CFB / Complement Factor B ELISA Kit
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Sandwich
96-Well Strip Plate
Human
6.25 - 400 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$730
CFB / Complement Factor B ELISA Kit
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Sandwich
96-Well Strip Plate
Mouse
0.39 - 25 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$854
CFB / Complement Factor B ELISA Kit
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Sandwich
96-Well Strip Plate
Rat
6.25 - 400 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
CFB / Complement Factor B ELISA Kit
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Sandwich
96-Well Strip Plate
Pig
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$669
CFB / Complement Factor B Protein
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E. coli
6His, N-terminus
86.9 kD
100 µg/$500; 1 mg/$1,679; 20 µg/$364
CFB / Complement Factor B ELISA Kit
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Sandwich
96-Well Microplate
Mouse
1.56 - 100 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
CFB / Complement Factor B ELISA Kit
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Sandwich
96-Well Strip Plate
Mouse
1.563 - 100 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$587
CFB / Complement Factor B ELISA Kit
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Competitive EIA
96-Well Strip Plate
Mouse
25 - 500 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum, Tissue Homogenates
1 Plate/$805
CFB / Complement Factor B ELISA Kit
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Sandwich
96-Well Strip Plate
Monkey
3.13 - 200 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$863
CFB / Complement Factor B ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rat
3.125 - 200 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$587
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Human Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
84.07kD
10 µg/$288; 50 µg/$442; 500 µg/$1,585; 1 mg/$2,157
CFB / Complement Factor B ELISA Kit
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Sandwich
96-Well Strip Plate
Rabbit
31.25 - 2000 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$728
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CFB / Complement Factor B Mouse anti-Human Monoclonal (N-Terminus) (014III-33.2.4.3) Antibody
Human
ELISA, Flo, IHC, IHC-Fr, WB
Unconjugated
0.1 ml/$568
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CFB / Complement Factor B Mouse anti-Human Monoclonal (FITC) Antibody
Human
ELISA, Flo, IHC, WB
FITC Conjugated
100 µl/$1,063
CFB / Complement Factor B ELISA Kit
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Sandwich
96-Well Strip Plate
Rhesus monkey
6.25 - 400 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$901
CFB / Complement Factor B Protein - Purified recombinant protein CFB was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
83 kDa
20 µg/$1,107
CFB / Complement Factor B Antibody - Human Small Intestine, Vessels: Formalin-Fixed, Paraffin-Embedded (FFPE)
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CFB / Complement Factor B Rabbit anti-Human Polyclonal (aa35-160) Antibody
Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
Viewing 1-25 of 185 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).