CFB / Complement Factor B

complement factor B

CFB / Complement Factor B is complement factor B, a component of the alternative pathway of complement activation. Factor B circulates in the blood as a single chain polypeptide. Upon activation of the alternative pathway, it is cleaved by complement factor D yielding the noncatalytic chain Ba and the catalytic subunit Bb. The active subunit Bb is a serine protease which associates with C3b to form the alternative pathway C3 convertase. Bb is involved in the proliferation of preactivated B lymphocytes, while Ba inhibits their proliferation. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. This cluster includes several genes involved in regulation of the immune reaction. Polymorphisms in this gene are associated with a reduced risk of age-related macular degeneration. The polyadenylation site of this gene is 421 bp from the 5' end of the gene for complement component 2.

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Products

Antibodies (140)

Type

Primary (140)

Target

CFB / Complement Factor B (140)

Reactivity

Human (85)

Mouse (46)

Rat (48)

Bovine (1)

Application

IHC (28)

IHC-Fr (4)

IHC-P (11)

WB (132)

Flo (18)

ELISA (38)

Func (1)

ICC (10)

ID (1)

IF (2)

IP (8)

Peptide-ELISA (2)

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Host

rabbit (106)

mouse (33)

goat (1)

Product Group

IHCPlus (4)

Isotype

IgG (35)

IgG1 (14)

IgG1 + IgG2b (1)

IgG2a (6)

IgG2b (2)

Clonality

monoclonal mc (33)

polyclonal pc (107)

Clone

014III-33.2.4.3 (1)

032B-22.1.X (1)

10-09 (1)

Format

APC (10)

APC Conjugated (11)

Azide-free (1)

Biotin Conjugated (19)

Cy3 Conjugated (10)

Cy7 Conjugated (10)

FITC Conjugated (19)

HRP Conjugated (16)

PE Conjugated (14)

Unconjugated (41)

Epitope

aa270-388 (18)

aa34-159 (18)

aa35-160 (10)

aa269-382 (8)

aa32-157 (8)

aa474-590 (8)

aa476-592 (8)

aa477-600 (8)

aa469-494 (7)

N-Terminus (2)

210-290 aa, Internal (1)

Cleaved-Lys260 (1)

Internal (1)

aa23-761 (1)

aa241-290 (1)

aa26-764 (1)

aa395-422 (1)

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Publications

No (140)

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IHC-plus™ CFB / Complement Factor B Antibody LS-B7934

(4.0) Rating

Antibody:

CFB / Complement Factor B Goat anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ID, IHC, IHC-P

Format:

Unconjugated

Price:

1 ml/$485

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IHC-plus™ CFB / Complement Factor B Antibody (aa23-761) LS-B13829

(4.0) Rating

Antibody:

CFB / Complement Factor B Rabbit anti-Human Polyclonal (aa23-761) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µg/$460

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CFB / Complement Factor B Antibody (HRP) LS-C318647

Antibody:

CFB / Complement Factor B Rabbit anti-Human Polyclonal (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

HRP Conjugated

Price:

50 µg/$294; 100 µg/$360

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CFB / Complement Factor B Antibody (Biotin) LS-C318646

Antibody:

CFB / Complement Factor B Rabbit anti-Human Polyclonal (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

Biotin Conjugated

Price:

50 µg/$294; 100 µg/$360

• Unconjugated
• HRP
• Biotin

• Unconjugated
• HRP
• Biotin

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CFB / Complement Factor B Antibody (aa474-590) LS-C294091

Antibody:

CFB / Complement Factor B Rabbit anti-Mouse Polyclonal (aa474-590) Antibody

Reactivity:

Mouse, Rat

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$311; 200 µl/$355; 500 µl/$499; 1 ml/$571; 2 ml/$777; 5 ml/$1,261

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CFB / Complement Factor B Antibody (aa474-590, Biotin) LS-C299905

Antibody:

CFB / Complement Factor B Rabbit anti-Mouse Polyclonal (aa474-590) (Biotin) Antibody

Reactivity:

Mouse, Rat

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$321; 200 µl/$369; 500 µl/$527; 1 ml/$611; 2 ml/$842; 5 ml/$1,387

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CFB / Complement Factor B Antibody (aa474-590, PE) LS-C724926

Antibody:

CFB / Complement Factor B Rabbit anti-Mouse Polyclonal (aa474-590) (PE) Antibody

Reactivity:

Mouse, Rat

Applications:

WB

Format:

PE Conjugated

Price:

100 µl/$412; 200 µl/$499; 500 µl/$869; 1 ml/$1,030; 2 ml/$1,345; 5 ml/$2,521

• Unconjugated
• Biotin
• PE

• Unconjugated
• Biotin
• PE

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CFB / Complement Factor B Antibody (aa241-290) LS-C121072

Antibody:

CFB / Complement Factor B Rabbit anti-Human Polyclonal (aa241-290) Antibody

Reactivity:

Mouse, Human

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µl/$334; 100 µl/$397

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CFB / Complement Factor B Antibody (aa32-157) LS-C294087

Antibody:

CFB / Complement Factor B Rabbit anti-Mouse Polyclonal (aa32-157) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$311; 200 µl/$355; 500 µl/$499; 1 ml/$571

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CFB / Complement Factor B Antibody LS-C331647

Antibody:

CFB / Complement Factor B Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

20 µl/$275; 100 µl/$389

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CFB / Complement Factor B Antibody (N-Terminus, clone 014III-33.2.4.3) LS-C44996

Antibody:

CFB / Complement Factor B Mouse anti-Human Monoclonal (N-Terminus) (014III-33.2.4.3) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, IHC, IHC-Fr, WB

Format:

Unconjugated

Price:

0.1 ml/$568

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CFB / Complement Factor B Antibody (aa35-160) LS-B15001

Antibody:

CFB / Complement Factor B Rabbit anti-Human Polyclonal (aa35-160) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$460

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CFB / Complement Factor B Antibody LS-C660252

Antibody:

CFB / Complement Factor B Mouse anti-Human Monoclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

100 µg/$351

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CFB / Complement Factor B Antibody (aa270-388) LS-B13934

Antibody:

CFB / Complement Factor B Rabbit anti-Human Polyclonal (aa270-388) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$460

Select

CFB / Complement Factor B Antibody (aa26-764) LS-C35973

Antibody:

CFB / Complement Factor B Mouse anti-Human Monoclonal (aa26-764) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$884

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CFB / Complement Factor B Antibody (aa469-494) LS-C327100

Antibody:

CFB / Complement Factor B Rabbit anti-Human Polyclonal (aa469-494) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

200 µl/$734

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CFB / Complement Factor B Antibody LS-C806225

Antibody:

CFB / Complement Factor B Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, IHC, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

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CFB / Complement Factor B Antibody LS-C123312

Antibody:

CFB / Complement Factor B Mouse anti-Human Monoclonal Antibody

Reactivity:

Human

Applications:

ELISA, Flo, Func, IHC, IHC-Fr, IHC-P, WB

Format:

Unconjugated

Price:

100 µg/$872

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CFB / Complement Factor B Antibody (Biotin) LS-C525131

Antibody:

CFB / Complement Factor B Mouse anti-Human Monoclonal (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, IHC, WB

Format:

Biotin Conjugated

Price:

100 µl/$1,063

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CFB / Complement Factor B Antibody (FITC) LS-C535147

Antibody:

CFB / Complement Factor B Mouse anti-Human Monoclonal (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, IHC, WB

Format:

FITC Conjugated

Price:

100 µl/$1,063

• Unconjugated
• Biotin
• FITC

• Unconjugated
• Biotin
• FITC

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CFB / Complement Factor B Antibody LS-C123311

Antibody:

CFB / Complement Factor B Mouse anti-Human Monoclonal Antibody

Reactivity:

Human

Applications:

ELISA, Flo, IHC, IHC-Fr, WB

Format:

Unconjugated

Price:

100 µg/$794

Select

CFB / Complement Factor B Antibody (Biotin) LS-C525130

Antibody:

CFB / Complement Factor B Mouse anti-Human Monoclonal (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, IHC, WB

Format:

Biotin Conjugated

Price:

100 µl/$1,022

Select

CFB / Complement Factor B Antibody (FITC) LS-C535145

Antibody:

CFB / Complement Factor B Mouse anti-Human Monoclonal (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, IHC, WB

Format:

FITC Conjugated

Price:

100 µl/$1,022

• Unconjugated
• Biotin
• FITC

• Unconjugated
• Biotin
• FITC

Select

CFB / Complement Factor B Antibody LS-C833934

Antibody:

CFB / Complement Factor B Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, IHC, WB

Format:

Unconjugated

Price:

60 µl/$331; 120 µl/$403; 200 µl/$529

Select

CFB / Complement Factor B Antibody (aa34-159) LS-C293491

Antibody:

CFB / Complement Factor B Rabbit anti-Rat Polyclonal (aa34-159) Antibody

Reactivity:

Mouse, Rat

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$317; 200 µl/$363; 500 µl/$515; 1 ml/$591; 2 ml/$816; 5 ml/$1,331

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