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| Catalog Number | Size | Price |
|---|---|---|
| LS-C43742-0.1 | 0.1 mg (0.1 mg/ml) | $444 |
Monoclonal Mouse anti‑Rat CD71 / Transferrin Receptor Antibody (clone OX‑26, FITC) LS‑C43742
Monoclonal Mouse anti‑Rat CD71 / Transferrin Receptor Antibody (clone OX‑26, FITC) LS‑C43742
Antibody:
CD71 / Transferrin Receptor Mouse anti-Rat Monoclonal (FITC) (OX-26) Antibody
Application:
Flo
Reactivity:
Rat
Format:
FITC, Unmodified
Other formats:
Toll Free North America
(800) 227-6666
(800) 227-6666For Research Use Only
Overview
Antibody:
CD71 / Transferrin Receptor Mouse anti-Rat Monoclonal (FITC) (OX-26) Antibody
Application:
Flo
Reactivity:
Rat
Format:
FITC, Unmodified
Other formats:
Specifications
Description
Transferrin Receptor antibody LS-C43742 is an FITC-conjugated mouse monoclonal antibody to rat Transferrin Receptor (CD71). Validated for Flow.
Target
Rat CD71 / Transferrin Receptor
Synonyms
TFRC | CD71 | TFR1 | TRFR | TFR | TR | CD71 antigen | p90 | T9 | Transferrin receptor | Transferrin receptor protein 1
Host
Mouse
Reactivity
Rat
(tested or 100% immunogen sequence identity)
Clonality
IgG2a
Monoclonal
Clone
OX-26
Conjugations
FITC.
Also available conjugated with RPE.
Purification
Protein G purified
Modifications
Unmodified
Immunogen
PHA activated rat lymphocytes
Specificity
Recognizes rat CD71, also known as transferrin receptor, a homodimeric type II transmembrane protein, expressed by all proliferating cells and cells with a requirement for iron, including reticulocytes and capillary endothelium in brain. Clone 0X-26 also binds to a number of non-dividing normal tissues. The balance between a sufficient amount of iron uptake and prevention of accumulation of excess iron within a cell, is vitally important to maintain cellular functions such as oxygen and electron transport and mitochondrial energy metabolism, whilst preventing permanent cell and tissue damage. Transferrin receptor (CD71), transferrin and ferritin have been identified as specialized proteins which control the uptake, transport and storage of free iron in tissues, thereby maintaining iron homeostasis. An imbalance in iron homeostasis within the brain has been linked with the neurodegenerative diseases, Alzheimer's, Parkinson's, Huntington's and Multiple Sclerosis. Is reported as suitable for use in immunoelectron microscopy. OX-26 detects a band of ~95kD in Western blotting under reducing conditions and ~195kD under non-reducing conditions reflecting it's homodimeric structure.
Applications
- Flow Cytometry (1:1)
- Applications tested for the base form of this product only
Usage
The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested. Flow Cytometry: Use 10 ul of the suggested working dilution to label 10^6 cells in 100 ul.
Presentation
PBS, 0.09% Sodium Azide, 1% BSA
Storage
Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Protect from light. Microcentrifugation recommended if solution contains precipitate.
Restrictions
For research use only. Intended for use by laboratory professionals.
About CD71 / Transferrin Receptor
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Featured Products
Species:
Mouse
Applications:
IHC, IHC - Frozen, Flow Cytometry
Species:
Human, Mouse, Rat, Hamster, Chicken
Applications:
IHC - Paraffin, ICC, Immunofluorescence, Western blot, Immunoprecipitation, ELISA
Species:
Human, Mouse
Applications:
IHC, IHC - Paraffin, Western blot
Species:
Human
Applications:
IHC - Paraffin, Western blot, ELISA
Species:
Human, Mouse, Rat, Hamster, Chicken
Applications:
ICC, Western blot, Immunoprecipitation, ELISA
Species:
Rat
Applications:
IHC, IHC - Frozen, Immunoprecipitation, Flow Cytometry
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 11/22/2024
Date Requested: 11/22/2024
