Target
Human CD28
Synonyms
CD28 | CD28 antigen | CD28 antigen (Tp44) | Tp44 | CD28 molecule
Reactivity
Human
(tested or 100% immunogen sequence identity)
Clonality
IgG1,k
Monoclonal
Conjugations
Unconjugated.
Also available conjugated with
Biotin,
FITC,
RPE.
Purification
Protein A purified
Modifications
Unmodified.
Also available
Fab'2,
Azide-free.
Immunogen
Recombinant Human CD28 and HPB-MLT human tumor cells.
Specificity
CD28 expressed on T cells and also on BHK cells transfected with human CD28. This antibody has been characterized as a superagonist.
Applications
- Flow Cytometry
- ELISA
- Functional Assay
Usage
Function: ANC28.1 stimulates expression of IL-2 from CD28+ cells. Divalent ANC28.1 can induce Antigen Independent T cell proliferation. In combination with anti-CD81 mAb, it can prime naive T cells to acquire effector function independent of TCR ligation.
Presentation
50 mM Sodium Phosphate, pH 7.5, 150 mM NaCl, 100 mM KCl, 0.5 mg/ml Gentamicin
Storage
Store at 4°C. Do not freeze.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee