Target
Human CD28
Synonyms
CD28 | CD28 antigen | CD28 antigen (Tp44) | Tp44 | CD28 molecule
Reactivity
Human
(tested or 100% immunogen sequence identity)
Clonality
IgG1,k
Monoclonal
Conjugations
Unconjugated
Purification
Protein A purified
Modifications
Azide-free.
Also available
Unmodified or
Fab'2.
Immunogen
Recombinant Human CD28 and HPB-MLT human tumor cells.
Specificity
CD28 expressed on T cells and also on BHK cells transfected with human CD28. This antibody has been characterized as a superagonist.
Applications
- Flow Cytometry
- ELISA
- Functional Assay
Usage
Function: ANC28.1 stimulates expression of IL-2 from CD28+ cells. Divalent ANC28.1 can induce Antigen Independent T cell proliferation. In combination with anti-CD81 mAb, it can prime naive T cells to acquire effector function independent of TCR ligation. The applications listed have been tested for the unmodified form of this product. Other forms have not been tested.
Presentation
50 mM Sodium Phosphate, pH 7.5, 150 mM NaCl, 100 mM KCl
Storage
Store at 4°C. Do not freeze. Open under aseptic conditions.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee