Target
Human CD28
Synonyms
CD28 | CD28 antigen | CD28 antigen (Tp44) | Tp44 | CD28 molecule
Reactivity
Human
(tested or 100% immunogen sequence identity)
Clonality
IgG1,k
Monoclonal
Conjugations
R. Phycoerythrin.
Also available
Unconjugated or conjugated with
Biotin,
FITC.
Purification
Gel filtration
Immunogen
Recombinant Human CD28 and HPB-MLT human tumor cells.
Specificity
CD28 expressed on T cells and also on BHK cells transfected with human CD28. This antibody has been characterized as a superagonist.
Applications
- Flow Cytometry
- ELISA
- Functional Assay
- Applications tested for the base form of this product only
Usage
Function: ANC28.1 stimulates expression of IL-2 from CD28+ cells. Divalent ANC28.1 can induce Antigen Independent T cell proliferation. In combination with anti-CD81 mAb, it can prime naive T cells to acquire effector function independent of TCR ligation. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
Presentation
50 mM Sodium Phosphate, pH 7.5, 150 mM NaCl, 500 mM KCl, 0.04% Sodium Azide, 15% Glycerol, 0.2% BSA
Storage
Store at 4°C. Do not freeze. Protect from light.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee