Target
Human CCR10 / GPR2
Synonyms
CCR10 | C-C CKR-10 | CC-CKR-10 | CCR-10 | C-C chemokine receptor type 10 | CC chemokine receptor 10 | G-protein coupled receptor 2 | GPR2 | G protein-coupled receptor 2
Reactivity
Human, Monkey, Mouse, Bat, Bovine, Rabbit, Sheep
(tested or 100% immunogen sequence identity)
Purification
Immunogen affinity purified
Immunogen
A synthetic peptide corresponding to a sequence at the C-Terminus of human GPR2/CCR10(312-327 aa FLGLRFRQDLRRLLRG), different from the related rat and mouse sequences by one amino acid.
Specificity
Expressed at high levels in adult testis, small intestine, fetal lung, fetal kidney. Weaker expression was observed in many other adult tissues including spleen, thymus, lymph node, Peyer patches, colon, heart, ovary, peripheral blood lymphocytes, thyroid and spinal cord. Also expressed by melanocytes, dermal fibroblasts, dermal microvascular endothelial cells. Also detected in T-cells and in skin-derived Langerhans cells. .