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| Catalog Number | Size | Price |
|---|---|---|
| LS-A1152-50 | 50 µg (1 mg/ml) | $460 |
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PathPlus™ Polyclonal Rabbit anti‑Human CCR10 / GPR2 Antibody (Extracellular Domain, IHC) LS‑A1152
PathPlus™ Polyclonal Rabbit anti‑Human CCR10 / GPR2 Antibody (Extracellular Domain, IHC) LS‑A1152
Antibody:
CCR10 / GPR2 Rabbit anti-Human Polyclonal (Extracellular Domain) Antibody
Application:
IHC, IHC-P
Reactivity:
Human, Bat, Dog, Pig
Format:
Unconjugated, Unmodified
Overview
Antibody:
CCR10 / GPR2 Rabbit anti-Human Polyclonal (Extracellular Domain) Antibody
Application:
IHC, IHC-P
Reactivity:
Human, Bat, Dog, Pig
Format:
Unconjugated, Unmodified
Specifications
Description
Chemokine (C-C motif) receptor 10 (CCR10) is a chemokine receptor that binds CCL27 and CCL28. CCR10-CCL27 interactions are involved in T cell-mediated skin inflammation (Homey et al., 2002 [PubMed 11821900]). In immunohistochemistry, CCL27 has membranous positivity on melanocytes in the skin, plasma cells and T cells, and is found in the central nervous system, gastrointestinal tract, muscle, endocrine tissues and the lung.
References: The UniProt Consortium. Nucleic Acids Res. 47: D506-515 (2019); Nucleic Acids Res. 2016 Jan 4;44(D1):D733-45, PMID:26553804
Target
Human CCR10 / GPR2
Synonyms
CCR10 | C-C CKR-10 | CC-CKR-10 | CCR-10 | C-C chemokine receptor type 10 | CC chemokine receptor 10 | G-protein coupled receptor 2 | GPR2 | G protein-coupled receptor 2
Host
Rabbit
Reactivity
Human, Bat, Dog, Pig
(tested or 100% immunogen sequence identity)
Predicted
Monkey, Bovine, Rabbit (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Immunogen
Synthetic 16 amino acid peptide from 2nd extracellular domain of human CCR10. Percent identity with other species by BLAST analysis: Human, Gorilla, Dog, Bat, Pig (100%); Monkey, Marmoset, Bovine, Panda, Rabbit (94%); Gibbon, Mouse, Rat, Hamster, Elephant (88%).
Epitope
Extracellular Domain
Specificity
Human CCR10. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Applications
- IHC
- IHC - Paraffin (11 - 44 µg/ml)
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Presentation
PBS, 0.1% Sodium Azide
Storage
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
About CCR10 / GPR2
Validation
Brain, Glioblastoma
Brain, Glioblastoma
Brain, cortex, neurons
Brain, cortex, neurons
Anti-CCR10 antibody IHC of human thymus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-CCR10 antibody IHC of human thymus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-CCR10 / GPR2 antibody IHC of human Colon, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-CCR10 / GPR2 antibody IHC of human Colon, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
See More About...
LSBio Ratings
PathPlus™ CCR10 / GPR2 Antibody (Extracellular Domain) for IHC LS-A1152 has an LSBio Rating of
Laboratory Validation Score (5)
Learn more about The LSBio Ratings Algorithm
Publications (0)
Customer Reviews (0)
Featured Products
Species:
Human
Applications:
IHC, IHC - Paraffin
Species:
Human
Applications:
IHC, IHC - Paraffin, ELISA
Species:
Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Pig
Applications:
IHC, IHC - Paraffin, ELISA
Species:
Human
Applications:
IHC, IHC - Paraffin, Western blot, Flow Cytometry
Species:
Human
Applications:
IHC, IHC - Paraffin
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 12/21/2024
Date Requested: 12/21/2024
