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| Catalog Number | Size | Price |
|---|---|---|
| LS-C498460-50 | 50 µg | $294 |
| LS-C498460-100 | 100 µg | $360 |
Polyclonal Rabbit anti‑Human BUB3 Antibody (Biotin) LS‑C498460
Polyclonal Rabbit anti‑Human BUB3 Antibody (Biotin) LS‑C498460
Antibody:
BUB3 Rabbit anti-Human Polyclonal (Biotin) Antibody
Application:
ELISA
Reactivity:
Human
Format:
Biotin, Unmodified
Other formats:
Toll Free North America
(800) 227-6666
(800) 227-6666For Research Use Only
Overview
Antibody:
BUB3 Rabbit anti-Human Polyclonal (Biotin) Antibody
Application:
ELISA
Reactivity:
Human
Format:
Biotin, Unmodified
Other formats:
Specifications
Description
BUB3 antibody LS-C498460 is a biotin-conjugated rabbit polyclonal antibody to human BUB3. Validated for ELISA.
Target
Human BUB3
Synonyms
BUB3 | Budding uninhibited by benomyl | HBUB3 | BUB3L | Mitotic checkpoint component
Host
Rabbit
Reactivity
Human
(tested or 100% immunogen sequence identity)
Clonality
IgG
Polyclonal
Conjugations
Purification
Protein G purified
Modifications
Unmodified
Immunogen
Recombinant human Mitotic checkpoint protein BUB3 protein (6-217AA)
Specificity
Has a dual function in spindle-assembly checkpoint signaling and in promoting the establishment of correct kinetochore-microtubule (K-MT) attachments. Promotes the formation of stable end-on bipolar attachments. Necessary for kinetochore localization of BUB1. Regulates chromosome segregation during oocyte meiosis. The BUB1/BUB3 complex plays a role in the inhibition of anaphase-promoting complex or cyclosome (APC/C) when spindle-assembly checkpoint is activated and inhibits the ubiquitin ligase activity of APC/C by phosphorylating its activator CDC20. This complex can also phosphorylate MAD1L1.
Applications
- ELISA
- Applications tested for the base form of this product only
Presentation
PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol.
Storage
Short term: -20°C; Long term: -80°C; Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
About BUB3
Publications (0)
Customer Reviews (0)
Featured Products
Species:
Drosophila melanogaster
Applications:
Western blot, ELISA
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 12/4/2024
Date Requested: 12/4/2024
