Target
Human ALK-6 / BMPR1B
Synonyms
BMPR1B | Activin receptor-like kinase 6 | ALK-6 | Bmp receptor 1b | Bmp receptor ib | BMP receptor type IB | CDw293 | CFK-43a | BMPR-1B | ALK6 | Type IB BMPR | BMP type-1B receptor | BMPR-IB | CDw293 antigen | Type IB BMP receptor
Reactivity
Human
(tested or 100% immunogen sequence identity)
Conjugations
Horseradish Peroxidase.
Also available
Unconjugated or conjugated with
Biotin,
FITC.
Immunogen
Recombinant Human Bone morphogenetic protein receptor type-1B protein (14-126AA)
Specificity
On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for BMP7/OP-1 and GDF5. Positively regulates chondrocyte differentiation through GDF5 interaction.