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ALK-6 / BMPR1B
bone morphogenetic protein receptor, type IB
ALK-6 / BMPR1B is a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. Mutations in this gene have been associated with primary pulmonary hypertension. Several transcript variants encoding two different isoforms have been found for this gene.
| Gene Name: | bone morphogenetic protein receptor, type IB |
| Family/Subfamily: | Protein Kinase , Activin/TGFb |
| Synonyms: | BMPR1B, Activin receptor-like kinase 6, ALK-6, Bmp receptor 1b, Bmp receptor ib, BMP receptor type IB, CDw293, CFK-43a, BMPR-1B, ALK6, Type IB BMPR, BMP type-1B receptor, BMPR-IB, CDw293 antigen, Type IB BMP receptor |
| Target Sequences: | NM_001203 NP_001194.1 O00238 |
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ALK-6 / BMPR1B
(72)
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(23)
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ALK-6 / BMPR1B Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, IHC-P, WB
Unconjugated
50 µl/$460
ALK-6 / BMPR1B Mouse anti-Human Monoclonal (aa27-150) (PE) (10K52) Antibody
Human
Flo
PE Conjugated
100 Tests/$836
ALK-6 / BMPR1B Mouse anti-Human Monoclonal (Extracellular Domain) (APC) Antibody
Human
Flo
APC Conjugated
100 Tests/$907
ALK-6 / BMPR1B Rabbit anti-Human Polyclonal (aa1-30) Antibody
Mouse, Human
ELISA, WB
Unconjugated
200 µl/$734
ALK-6 / BMPR1B Rabbit anti-Human Polyclonal (aa1-30) (Biotin) Antibody
Mouse, Human
ELISA, WB
Biotin Conjugated
200 µl/$952
ALK-6 / BMPR1B Rabbit anti-Human Polyclonal Antibody
Rat, Human
ELISA, IF, IHC, WB
Unconjugated
50 µg/$294; 100 µg/$360
ALK-6 / BMPR1B Rabbit anti-Human Polyclonal (aa145-160) Antibody
Mouse, Rat, Human
WB
Unconjugated
10 µg/$318; 100 µg/$470
ALK-6 / BMPR1B Mouse anti-Human Monoclonal (2F3) Antibody
Human
ELISA, RNAi, WB
Unconjugated
100 µg/$423
ALK-6 / BMPR1B Rabbit anti-Human Polyclonal (aa472-502) Antibody
Human
IHC, IHC-P, WB
Unconjugated
400 µl/$393
ALK-6 / BMPR1B Rabbit anti-Human Polyclonal Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µg/$575
ALK-6 / BMPR1B Rabbit anti-Mouse Polyclonal (aa133-160) Antibody
Mouse, Human
WB
Unconjugated
400 µl/$393
E. coli
His
20 µg/$361; 100 µg/$739; 4 µg/$261
ALK-6 / BMPR1B Rabbit anti-Human Polyclonal (aa472-502) Antibody
Human
ELISA, IHC, WB
Unconjugated
200 µl/$734
ALK-6 / BMPR1B Rabbit anti-Human Polyclonal (aa472-502) (Biotin) Antibody
Human
ELISA, IHC, WB
Biotin Conjugated
200 µl/$952
ALK-6 / BMPR1B Rabbit anti-Human Polyclonal (aa472-502) (FITC) Antibody
Human
ELISA, IHC, WB
FITC Conjugated
200 µl/$952
ALK-6 / BMPR1B Rabbit anti-Human Polyclonal (aa472-502) (APC) Antibody
Human
ELISA, IHC, WB
APC Conjugated
200 µl/$952
ALK-6 / BMPR1B Rabbit anti-Human Polyclonal (aa472-502) (PE) Antibody
Human
ELISA, IHC, WB
PE Conjugated
200 µl/$952
ALK-6 / BMPR1B Rabbit anti-Human Polyclonal (aa472-502) (Azide-free) (HRP) Antibody
Human
ELISA, IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
ALK-6 / BMPR1B Rabbit anti-Human Polyclonal (aa134-162) Antibody
Human
ELISA, IHC, WB
Unconjugated
200 µl/$734
ALK-6 / BMPR1B Rabbit anti-Human Polyclonal (aa134-162) (Biotin) Antibody
Human
ELISA, IHC, WB
Biotin Conjugated
200 µl/$952
ALK-6 / BMPR1B Rabbit anti-Human Polyclonal (aa134-162) (FITC) Antibody
Human
ELISA, IHC, WB
FITC Conjugated
200 µl/$952
ALK-6 / BMPR1B Rabbit anti-Human Polyclonal (aa134-162) (APC) Antibody
Human
ELISA, IHC, WB
APC Conjugated
200 µl/$952
ALK-6 / BMPR1B Rabbit anti-Human Polyclonal (aa134-162) (PE) Antibody
Human
ELISA, IHC, WB
PE Conjugated
200 µl/$952
ALK-6 / BMPR1B Rabbit anti-Human Polyclonal (aa134-162) (Azide-free) (HRP) Antibody
Human
ELISA, IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
ALK-6 / BMPR1B Rabbit anti-Human Polyclonal (aa14-184) Antibody
Human
IHC, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
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