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Catalog Number	Size	Price
LS-C359243-0.1	0.1 ml (1 mg/ml)	$386

ACAN / Aggrecan Antibody - Immunohistochemistry: Aggrecan Neoepitope Antibody - Analysis of ACAN in mouse cartilage with hematoxylin counterstain. This image was taken for the unconjugated form of this product. Other forms have not been tested.

ACAN / Aggrecan Antibody - Immunocytochemistry/Immunofluorescence: Aggrecan Neoepitope Antibody - Detection of ACAN in OA cartilage using ACAN antibody. This image was taken for the unconjugated form of this product. Other forms have not been tested.

ACAN / Aggrecan Antibody - Western Blot: Aggrecan Neoepitope Antibody - Analysis of ACAN in U2OS cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.

ACAN / Aggrecan Antibody - Western Blot: Aggrecan Neoepitope Antibody - Analysis of ACAN in L929 whole cell extract using ACAN antibody. This image was taken for the unconjugated form of this product. Other forms have not been tested.

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Polyclonal Rabbit anti‑Human ACAN / Aggrecan Antibody (aa350‑400, IHC, IF, WB) LS‑C359243

Name: Anti-ACAN / Aggrecan Antibody | Rabbit anti-Human Polyclonal | LSBio
Brand: Lifespan BioSciences
SKU: LS-C359243-0.1
Price: 386.0000 USD
Availability: InStock

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Antibody:

ACAN / Aggrecan Rabbit anti-Human Polyclonal (aa350-400) Antibody

Application:

IHC, IHC-P, IHC-Fr, ICC, IF, WB, Flo

Reactivity:

Human, Mouse, Rat, Bovine, Dog, Pig

Format:

Unconjugated, Unmodified

Other formats:

Biotin DY650 DY488 DY550

$386

LS-C359243-0.1

Toll Free North America

(800) 227-6666

For Research Use Only

Specifications Validation Publications Reviews Featured Products Request SDS/MSDS

Overview

Antibody:

ACAN / Aggrecan Rabbit anti-Human Polyclonal (aa350-400) Antibody

Application:

IHC, IHC-P, IHC-Fr, ICC, IF, WB, Flo

Reactivity:

Human, Mouse, Rat, Bovine, Dog, Pig

Format:

Unconjugated, Unmodified

Other formats:

Biotin DY650 DY488 DY550

Specifications

Description

Aggrecan antibody LS-C359243 is an unconjugated rabbit polyclonal antibody to Aggrecan (ACAN) (aa350-400) from human. It is reactive with human, mouse, rat and other species. Validated for Flow, ICC, IF, IHC and WB.

Target

Human ACAN / Aggrecan

Synonyms

See All ACAN / Aggrecan Antibodies

Host

Rabbit

Reactivity

Human, Mouse, Rat, Bovine, Dog, Pig (tested or 100% immunogen sequence identity)

Clonality

Polyclonal

Conjugations

Unconjugated. Also available conjugated with Biotin, DY650, DY488, DY550.

Purification

Immunoaffinity purified

Modifications

Unmodified

Immunogen

A synthetic peptide corresponding to a region of human Aggrecan (within residues 350-400). [UniProt# P16112]

Epitope

aa350-400

Specificity

Human Aggrecan. Human Aggrecan. Aggrecan Neo (JSCNIT).

Applications

IHC
IHC - Paraffin (1:1000)
IHC - Frozen
ICC (1:20 - 1:100)
Immunofluorescence (1:20 - 1:100)
Western blot (1:1000)
Flow Cytometry

Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.

Usage

This Aggrecan Neoepitope antibody is useful for Immunocytochemistry/Immunofluorescence, Immunohistochemistry-paraffin embedded sections, and Western Blot. In WB a band is detected at ~61 kDa representing the neoepitope sequence (NITEGE) generated by aggrecanase-mediated cleavage at Glu373-Ala374 of aggrecan core proteins. Use in Immunohistochemistry-Frozen and Flow Cytometry reported in scientific literature (PMID 21482542)

Presentation

PBS, 0.1% Sodium Azide, 30% Glycerol

Storage

Short term: store at 4°C. Long term: store at -20°C. Avoid freeze-thaw cycles.

Restrictions

For research use only. Intended for use by laboratory professionals.

Guarantee

This antibody carries the LSBio 100% Guarantee.

LSBio Guarantee

About ACAN / Aggrecan

Uniprot: P16112 NCBI: NM_013227 NP_037359.3