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ZKSCAN3 / ZNF306
zinc finger with KRAB and SCAN domains 3
Transcriptional factor that binds to the consensus sequence 5'-[GT][AG][AGT]GGGG-3' and acts as a repressor of autophagy. Specifically represses expression of genes involved in autophagy and lysosome biogenesis/function such as MAP1LC3B, ULK1 or WIPI2. Associates with chromatin at the ITGB4 and VEGF promoters. Also acts as a transcription activator and promotes cancer cell progression and/or migation in various tumors and myelomas.
| Gene Name: | zinc finger with KRAB and SCAN domains 3 |
| Family/Subfamily: | Zinc Finger |
| Synonyms: | ZKSCAN3, DJ874C20.1, DJ874C20.1., KIAA0426, Zfp-47, ZFP306, Zinc finger protein 309, ZNF306, ZNF309, ZSCAN13, ZSCAN35, ZF47, Zinc finger protein 306, Zinc finger protein zfp47, Zfp47, Zinc finger protein 47 homolog |
| Target Sequences: | U71601 AAB16813.1 |
Publications (1)
1
Alcohol-Induced Lysosomal Damage and Suppression of Lysosome Biogenesis Contribute to Hepatotoxicity in HIV-Exposed Liver Cells. Moses New-Aaron , Paul G Thomes , Murali Ganesan , Raghubendra Singh Dagur , Terrence M Donohue Jr , Kharbanda K Kusum , Larisa Y Poluektova, Natalia A Osna. Biomolecules. 2021 Oct;11:1497. [Full Text Article]
[PubMed:34680130]
[PMC:PMC8533635]
Related Antibodies: LS-C501696.
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Antibodies
(15)
Type
Primary
(15)
Target
ZKSCAN3 / ZNF306
(15)
Reactivity
Human
(15)
Mouse
(3)
Chimpanzee
(3)
Gibbon
(3)
Monkey
(3)
Application
IHC
(3)
IHC-P
(1)
WB
(11)
ELISA
(8)
ICC
(1)
IF
(1)
Peptide-ELISA
(2)
Host
rabbit
(14)
mouse
(1)
Isotype
IgG
(12)
IgG2a,k
(1)
Clonality
monoclonal mc
(1)
polyclonal pc
(14)
Clone
2A5
(1)
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Biotin Conjugated
(2)
FITC Conjugated
(2)
HRP Conjugated
(2)
Unconjugated
(9)
Epitope
N-Terminus
(4)
aa1-394
(1)
aa100-130
(1)
aa175-440
(1)
Publications
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(14)
Yes
(1)
ZKSCAN3 / ZNF306 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IF, IHC, WB
Unconjugated
50 µg/$294; 100 µg/$360
ZKSCAN3 / ZNF306 Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA
HRP Conjugated
50 µg/$294; 100 µg/$360
ZKSCAN3 / ZNF306 Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA
Biotin Conjugated
50 µg/$294; 100 µg/$360
ZKSCAN3 / ZNF306 Rabbit anti-Human Polyclonal (FITC) Antibody
Human
ELISA
FITC Conjugated
50 µg/$294; 100 µg/$360
ZKSCAN3 / ZNF306 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
WB
Unconjugated
100 µl/$424
ZKSCAN3 / ZNF306 Rabbit anti-Human Polyclonal (N-Terminus) (HRP) Antibody
Human, Monkey, Chimpanzee, Gibbon
WB
HRP Conjugated
100 µl/$469
ZKSCAN3 / ZNF306 Rabbit anti-Human Polyclonal (N-Terminus) (Biotin) Antibody
Human, Monkey, Chimpanzee, Gibbon
WB
Biotin Conjugated
100 µl/$469
ZKSCAN3 / ZNF306 Rabbit anti-Human Polyclonal (N-Terminus) (FITC) Antibody
Human, Monkey, Chimpanzee, Gibbon
WB
FITC Conjugated
100 µl/$469
ZKSCAN3 / ZNF306 Rabbit anti-Human Polyclonal (aa1-394) Antibody
Human
ICC, IHC, IHC-P, WB
Unconjugated
100 µl/$450
ZKSCAN3 / ZNF306 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
ZKSCAN3 / ZNF306 Mouse anti-Human Monoclonal (2A5) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$335
ZKSCAN3 / ZNF306 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$351
ZKSCAN3 / ZNF306 Rabbit anti-Human Polyclonal (aa175-440) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$332
ZKSCAN3 / ZNF306 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
Peptide-ELISA, WB
Unconjugated
100 µl/$282; 200 µl/$350
ZKSCAN3 / ZNF306 Rabbit anti-Human Polyclonal (aa100-130) Antibody
Human
Peptide-ELISA, WB
Unconjugated
200 µl/$393
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