YES1 / c-Yes

v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1

Non-receptor protein tyrosine kinase that is involved in the regulation of cell growth and survival, apoptosis, cell-cell adhesion, cytoskeleton remodeling, and differentiation. Stimulation by receptor tyrosine kinases (RTKs) including EGRF, PDGFR, CSF1R and FGFR leads to recruitment of YES1 to the phosphorylated receptor, and activation and phosphorylation of downstream substrates. Upon EGFR activation, promotes the phosphorylation of PARD3 to favor epithelial tight junction assembly. Participates in the phosphorylation of specific junctional components such as CTNND1 by stimulating the FYN and FER tyrosine kinases at cell-cell contacts. Upon T-cell stimulation by CXCL12, phosphorylates collapsin response mediator protein 2/DPYSL2 and induces T-cell migration. Participates in CD95L/FASLG signaling pathway and mediates AKT-mediated cell migration. Plays a role in cell cycle progression by phosphorylating the cyclin-dependent kinase 4/CDK4 thus regulating the G1 phase. Also involved in G2/M progression and cytokinesis.

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Products

Antibodies (30)

Proteins (6)

Type

Over-Expression Lysate (2)

Primary (30)

Recombinant (4)

Target

YES1 / c-Yes (36)

Reactivity

Human (29)

Mouse (12)

Rat (2)

Horse (1)

Application

IHC (14)

IHC-P (5)

WB (27)

ELISA (21)

ICC (1)

IF (2)

IP (1)

Peptide-ELISA (2)

Host

rabbit (25)

mouse (5)

Product Group

IHCPlus (2)

Isotype

IgG (19)

IgG1 (3)

IgG1,k (2)

Clonality

monoclonal mc (5)

polyclonal pc (25)

Clone

1612CT505.7.50 (1)

2D5 (1)

2F3E6 (2)

Format

APC Conjugated (2)

Azide-free (2)

Biotin Conjugated (3)

FITC Conjugated (3)

HRP Conjugated (3)

PE Conjugated (2)

Unconjugated (17)

Epitope

aa1-30 (14)

Amino Acid: 10-193 (1)

aa148-182 (1)

aa416-538 (1)

aa7-35 (1)

Publications

No (36)

Tag

GST (1)

GST, N-terminus (1)

His-GST (1)

Myc-DDK (Flag) (3)

Species

Human (5)

Source

293T Cells (1)

Baculovirus (1)

HEK 293 Cells (2)

Wheat Germ Extract (2)

Purification

Purified (2)

Low Endotoxin Level

Low endotoxin level (1)

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IHC-plus™ YES1 / c-Yes Antibody LS-B4193

(4.0) Rating

Antibody:

YES1 / c-Yes Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

ICC, IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$460

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YES1 / c-Yes Antibody (aa416-538) LS-C179116

Antibody:

YES1 / c-Yes Rabbit anti-Human Polyclonal (aa416-538) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

100 µl/$332

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YES1 / c-Yes Antibody LS-C660664

Antibody:

YES1 / c-Yes Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IP, WB

Format:

Unconjugated

Price:

100 µg/$341

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YES1 / c-Yes Antibody (clone 2D5) LS-C133516

Antibody:

YES1 / c-Yes Mouse anti-Human Monoclonal (2D5) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$423

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YES1 / c-Yes Antibody LS-C500040

Antibody:

YES1 / c-Yes Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IF, IHC, WB

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

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IHC-plus™ YES1 / c-Yes Antibody LS-B14851

(4.0) Rating

Antibody:

YES1 / c-Yes Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$460

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YES1 / c-Yes Antibody (aa1-30) LS-C329125

Antibody:

YES1 / c-Yes Rabbit anti-Human Polyclonal (aa1-30) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

200 µl/$734

Select

YES1 / c-Yes Antibody (aa1-30, Biotin) LS-C284370

Antibody:

YES1 / c-Yes Rabbit anti-Human Polyclonal (aa1-30) (Biotin) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

Select

YES1 / c-Yes Antibody (aa1-30, FITC) LS-C284372

Antibody:

YES1 / c-Yes Rabbit anti-Human Polyclonal (aa1-30) (FITC) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC, WB

Format:

FITC Conjugated

Price:

200 µl/$952

Select

YES1 / c-Yes Antibody (aa1-30, APC) LS-C284369

Antibody:

YES1 / c-Yes Rabbit anti-Human Polyclonal (aa1-30) (APC) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC, WB

Format:

APC Conjugated

Price:

200 µl/$952

Select

YES1 / c-Yes Antibody (aa1-30, Azide-free, HRP) LS-C284371

Antibody:

YES1 / c-Yes Rabbit anti-Human Polyclonal (aa1-30) (Azide-free) (HRP) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

Select

YES1 / c-Yes Antibody (aa1-30, PE) LS-C284373

Antibody:

YES1 / c-Yes Rabbit anti-Human Polyclonal (aa1-30) (PE) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC, WB

Format:

PE Conjugated

Price:

200 µl/$952

• Unconjugated
• Biotin
• FITC
• APC
• HRP, Azide-free
• PE

• Unconjugated
• Biotin
• FITC
• More...
  • APC
  • HRP, Azide-free
  • PE

Select

YES1 / c-Yes Antibody (aa1-30) LS-C99398

Antibody:

YES1 / c-Yes Rabbit anti-Human Polyclonal (aa1-30) Antibody

Reactivity:

Mouse, Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

400 µl/$393

Select

YES1 / c-Yes Antibody (aa7-35) LS-C407676

Antibody:

YES1 / c-Yes Rabbit anti-Human Polyclonal (aa7-35) Antibody

Reactivity:

Horse, Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

10 µg/$318; 100 µg/$470

Select

YES1 / c-Yes Antibody LS-C490141

Antibody:

YES1 / c-Yes Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µg/$575

Select

YES1 / c-Yes Antibody (aa1-30) LS-C326412

Antibody:

YES1 / c-Yes Rabbit anti-Mouse Polyclonal (aa1-30) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

200 µl/$734

Select

YES1 / c-Yes Antibody (aa1-30, Biotin) LS-C273792

Antibody:

YES1 / c-Yes Rabbit anti-Human Polyclonal (aa1-30) (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

Select

YES1 / c-Yes Antibody (aa1-30, FITC) LS-C273794

Antibody:

YES1 / c-Yes Rabbit anti-Human Polyclonal (aa1-30) (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

FITC Conjugated

Price:

200 µl/$952

Select

YES1 / c-Yes Antibody (aa1-30, Azide-free, HRP) LS-C273793

Antibody:

YES1 / c-Yes Rabbit anti-Human Polyclonal (aa1-30) (Azide-free) (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

Select

YES1 / c-Yes Antibody (aa1-30, PE) LS-C273796

Antibody:

YES1 / c-Yes Rabbit anti-Human Polyclonal (aa1-30) (PE) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

PE Conjugated

Price:

200 µl/$952

Select

YES1 / c-Yes Antibody (aa1-30, APC) LS-C273791

Antibody:

YES1 / c-Yes Rabbit anti-Human Polyclonal (aa1-30) (APC) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

APC Conjugated

Price:

200 µl/$952

• Unconjugated
• Biotin
• FITC
• HRP, Azide-free
• PE
• APC

• Unconjugated
• Biotin
• FITC
• More...
  • HRP, Azide-free
  • PE
  • APC

Select

YES1 / c-Yes Antibody (clone 2F3E6) LS-C108741

Antibody:

YES1 / c-Yes Mouse anti-Human Monoclonal (2F3E6) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µl/$467

Select

YES1 / c-Yes Antibody LS-C812431

Antibody:

YES1 / c-Yes Mouse anti-Human Monoclonal Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

50 µg/$332; 100 µg/$404; 200 µg/$505

Select

YES1 / c-Yes Antibody (aa148-182) LS-C356534

Antibody:

YES1 / c-Yes Rabbit anti-Mouse Polyclonal (aa148-182) Antibody

Reactivity:

Mouse, Rat

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

400 µl/$393

Select

YES1 / c-Yes Antibody (clone 1612CT505.7.50) LS-C392587

Antibody:

YES1 / c-Yes Mouse anti-Human Monoclonal (1612CT505.7.50) Antibody

Reactivity:

Human

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

200 µl/$393

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