WNT5A

wingless-type MMTV integration site family, member 5A

Ligand for members of the frizzled family of seven transmembrane receptors. Can activate or inhibit canonical Wnt signaling, depending on receptor context. In the presence of FZD4, activates beta-catenin signaling. In the presence of ROR2, inhibits the canonical Wnt pathway by promoting beta-catenin degradation through a GSK3-independent pathway which involves down-regulation of beta-catenin-induced reporter gene expression. Suppression of the canonical pathway allows chondrogenesis to occur and inhibits tumor formation. Stimulates cell migration. Decreases proliferation, migration, invasiveness and clonogenicity of carcinoma cells and may act as a tumor suppressor. Mediates motility of melanoma cells. Required during embryogenesis for extension of the primary anterior-posterior axis and for outgrowth of limbs and the genital tubercle. Inhibits type II collagen expression in chondrocytes.

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Products

Antibodies (44)

Proteins (13)

ELISA Kits (12)

Type

Development Kit (3)

Over-Expression Lysate (2)

Primary (44)

Recombinant (11)

Sandwich (8)

Sandwich CLIA (1)

Target

WNT5A (69)

Reactivity

Human (50)

Mouse (24)

Rat (11)

Bat (3)

Bovine (4)

Dog (3)

Gibbon (3)

Guinea pig (3)

Monkey (1)

Pig (3)

Rabbit (3)

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Application

IHC (31)

IHC-P (9)

WB (42)

Flo (5)

ELISA (12)

ICC (1)

IF (3)

Peptide-ELISA (1)

Host

rabbit (35)

mouse (8)

rat (1)

Product Group

DevKit DuoPlus (3)

IHCPlus (3)

Isotype

IgG (16)

IgG1 (6)

IgG2a (1)

IgG2a,k (2)

Clonality

monoclonal mc (9)

polyclonal pc (35)

Clone

3A4 (1)

3D10 (2)

6F2 (2)

Format

96-Well Strip Plate (9)

Antibody Pair and Standard (3)

APC (1)

APC Conjugated (3)

Atto 390 Conjugated (1)

Atto 488 Conjugated (1)

Atto 594 Conjugated (1)

Azide-free (1)

Biotin Conjugated (4)

Cy3 Conjugated (1)

Cy7 Conjugated (1)

FITC Conjugated (4)

HRP Conjugated (3)

PE Conjugated (2)

PerCP Conjugated (1)

RPE Conjugated (1)

Unconjugated (21)

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Epitope

aa62-381 (8)

aa185-213 (6)

aa180-229 (4)

aa184-303 (2)

Leu270 (1)

aa190-230 (1)

aa38-380 (1)

Publications

No (64)

Yes (5)

Sample Type

Cell Culture Supernatants (8)

Cell Lysates (6)

Plasma (6)

Serum (6)

Tissue Homogenates (10)

Tag

10His, N-terminus + Myc, C-terminus (1)

10His-SUMO, N-terminus + Myc, C-terminus (1)

6His, N-terminus (3)

6His-SUMO, N-terminus (1)

GST (2)

GST, N-terminus (2)

Myc-DDK (Flag) (3)

Species

Human (10)

Mouse (2)

Source

293T Cells (1)

E. coli (7)

HEK 293 Cells (2)

Wheat Germ Extract (2)

Yeast (1)

Purification

Purified (6)

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IHC-plus™ WNT5A Antibody (clone 6F2) LS-B3859

(5.0) Rating

(2) Publication(s)

Antibody:

WNT5A Mouse anti-Human Monoclonal (6F2) Antibody

Reactivity:

Human

Applications:

ELISA, IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$460

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WNT5A Antibody (aa180-229) LS-B4565

(4.2) Rating

(3) Publication(s)

Antibody:

WNT5A Rabbit anti-Human Polyclonal (aa180-229) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$460

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WNT5A Antibody (aa180-229, Biotin) LS-C427387

Antibody:

WNT5A Rabbit anti-Human Polyclonal (aa180-229) (Biotin) Antibody

Reactivity:

Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Pig, Bat, Gibbon, Human

Applications:

IHC, IHC-P, WB

Format:

Biotin Conjugated

Price:

100 µl/$469

• Unconjugated
• Biotin

• Unconjugated
• Biotin

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IHC-plus™ WNT5A Antibody (clone 3D10) LS-B3878

(4.0) Rating

Antibody:

WNT5A Mouse anti-Human Monoclonal (3D10) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$460

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WNT5A Antibody (aa190-230) LS-C47384

(4.0) Rating

(1) Publication(s)

Antibody:

WNT5A Rabbit anti-Human Polyclonal (aa190-230) Antibody

Reactivity:

Mouse, Bovine, Rat, Human, Monkey

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µg/$386

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WNT5A Antibody (clone 3A4) LS-C133974

(4.0) Rating

(1) Publication(s)

Antibody:

WNT5A Mouse anti-Human Monoclonal (3A4) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P

Format:

Unconjugated

Price:

100 µg/$423

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Mouse/Human/Rat WNT5A (Sandwich ELISA) ELISA Kit - LS-F6742

(4.0) Rating

(1) Publication(s)

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse, Human, Rat

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates, Tissue Homogenates

Price:

1 Plate/$811

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Human WNT5A (Sandwich ELISA) ELISA Kit - LS-F12975

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$669

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Rat WNT5A (Sandwich ELISA) ELISA Kit - LS-F15714

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

0.31 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$669

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Mouse WNT5A (Sandwich ELISA) ELISA Kit - LS-F15715

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

0.312 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$669

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Mouse WNT5A (Sandwich ELISA) ELISA Kit - LS-F35768

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

0.313 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

Select

Human WNT5A (Sandwich ELISA) ELISA Kit - LS-F35770

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

Select

Human WNT5A (Sandwich ELISA) ELISA Kit - LS-F55068

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates, Tissue Homogenates

Price:

1 Plate/$730

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WNT5A Antibody (aa38-380) LS-C124811

Antibody:

WNT5A Rat anti-Mouse Monoclonal (aa38-380) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

100 µg/$962

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Human WNT5A (CLIA) ELISA Kit - LS-F38871

Type:

Sandwich CLIA

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

13.7 - 10000 pg/ml

Detection:

Chemiluminescent

Sample Types:

Cell Culture Supernatants, Cell Lysates, Tissue Homogenates

Price:

1 Plate/$911

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Mouse WNT5A (Sandwich ELISA) ELISA Kit - LS-F53480

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

3.12 - 200 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$958

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Human WNT5A Protein (Recombinant 6His, N-terminus) (Full Length) - LS-G136612

Source:

Yeast

Tag:

6His, N-terminus

Molecular Weight:

37.8 kDa

Price:

100 µg/$446; 20 µg/$336; 1 mg/$1,460

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WNT5A Antibody (aa185-213) LS-C326370

Antibody:

WNT5A Rabbit anti-Human Polyclonal (aa185-213) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, IHC, WB

Format:

Unconjugated

Price:

200 µl/$734

Select

WNT5A Antibody (aa185-213, Biotin) LS-C273621

Antibody:

WNT5A Rabbit anti-Human Polyclonal (aa185-213) (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, IHC, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

• Unconjugated
• Biotin

• Unconjugated
• Biotin

Select

Mouse WNT5A Protein (Recombinant GST) (aa62-380) - LS-G16280

Source:

E. coli

Tag:

GST

Molecular Weight:

62.2 kDa

Price:

10 µg/$291; 50 µg/$502; 100 µg/$802; 200 µg/$1,002; 1 mg/$2,144; 500 µg/$1,668; 5 mg/$3,501; 2 mg/$2,334

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WNT5A Antibody LS-C331923

Antibody:

WNT5A Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

20 µl/$275; 100 µl/$389

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WNT5A Antibody (aa62-381) LS-C297021

Antibody:

WNT5A Rabbit anti-Mouse Polyclonal (aa62-381) Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$321; 200 µl/$369; 500 µl/$527; 1 ml/$611; 2 ml/$842; 5 ml/$1,387

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WNT5A Antibody (aa62-381, Biotin) LS-C297722

Antibody:

WNT5A Rabbit anti-Mouse Polyclonal (aa62-381) (Biotin) Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$333; 200 µl/$385; 500 µl/$559; 1 ml/$671; 2 ml/$907; 5 ml/$1,525

• Unconjugated
• Biotin

• Unconjugated
• Biotin

Select

WNT5A Antibody (clone 6F2) LS-C758764

Antibody:

WNT5A Mouse anti-Human Monoclonal (6F2) Antibody

Reactivity:

Rat, Human

Applications:

ICC, IF, IHC, WB

Format:

Unconjugated

Price:

100 µl/$541

Select

WNT5A Antibody LS-C812860

Antibody:

WNT5A Mouse anti-Human Monoclonal Antibody

Reactivity:

Human

Applications:

ELISA, IF, IHC, WB

Format:

Unconjugated

Price:

50 µg/$332; 100 µg/$404; 200 µg/$505

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