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Vector Laboratories, Inc.
6737 Mowry Ave
Newark, CA 94560
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Customer Service: (800) 227-6666 / (650) 697-3600
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VCAM1 / CD106
vascular cell adhesion molecule 1
Vascular cell adhesion molecule 1, VCAM-1, is a surface glycoprotein expressed by cytokine-activated endothelium that mediates the adhesion of monocytes and lymphocytes. VCAM-1 and integrin alpha-4-beta-1 facilitate a critical cell-cell adhesion event required for survival of endothelial and mural cells during vascularization. Studies of heart development have shown that deficiencies of VCAM and in alpha-4 integrin also result in epicardial dissolution and subsequent myocardial thinning.
| Gene Name: | vascular cell adhesion molecule 1 |
| Family/Subfamily: | ICAM , not assigned-ICAM |
| Synonyms: | VCAM1, CD106, CD106 antigen, INCAM-100, V-CAM 1, VCAM-1 |
| Target Sequences: | NM_001078 NP_001069.1 P19320 |
Publications (2)
1
Renal denervation and CD161a immune ablation prevent cholinergic hypertension and renal sodium retention. Nandita Raikwar, Cameron Braverman, Peter M Snyder, Robert A Fenton, David K Meyerholz, Francois M Abboud, Sailesh C Harwani. American journal of physiology. Heart and circulatory physiology. 2019 September;317:H517-H530. [Full Text Article]
[PubMed:31172810]
[PMC:PMC6766722]
2
SPARC Production by Bone Marrow-Derived Cells Contributes to Myocardial Fibrosis in Pressure-Overload. Hannah J Riley, Ryan R Kelly, An O Van Laer, Lily S Neff, Shaoni Dasgupta, Catalin F Baicu, Lindsay T McDonald, Amanda C LaRue, Michael R Zile, Amy D Bradshaw. American journal of physiology. Heart and circulatory physiology. 2020 December; [Full Text Article]
[PubMed:33306449]
Related Antibodies: LS-C661877.
☰ Filters
Products
Proteins
(27)
Type
Over-Expression Lysate
(2)
Recombinant
(25)
Target
VCAM1 / CD106
(27)
Publications
No
(27)
Tag
6His, C-terminus
(2)
6His, N-terminus
(2)
Fc
(1)
Fc, C-terminus
(1)
GST
(1)
GST, N-terminus
(1)
His
(5)
His-Fc
(1)
His-S
(1)
His-SUMO
(1)
His-T7
(3)
Myc-DDK (Flag)
(4)
Species
Dog
(1)
Human
(14)
Mouse
(7)
Rabbit
(1)
Rat
(2)
Rhesus monkey
(1)
Source
293T Cells
(1)
CHO Cells
(1)
E. coli
(10)
HEK 293 Cells
(5)
Human
(1)
Human Cells
(4)
Mammalian Cells
(2)
Wheat Germ Extract
(2)
Yeast
(1)
Purification
Purified
(7)
Low Endotoxin Level
Low endotoxin level
(10)
Biologically Active
Biologically active
(3)
E. coli
6His, N-terminus
77.4 kD
1 mg/$1,679; 100 µg/$500; 20 µg/$364
HEK 293 Cells
Myc-DDK (Flag)
78.7 kDa
20 µg/$1,107
E. coli
His-T7
29.9 kDa
10 µg/$287; 50 µg/$482; 100 µg/$770; 200 µg/$962; 1 mg/$2,094; 500 µg/$1,623; 5 mg/$3,361; 2 mg/$2,284
Human
None
Less than 1.0 EU/µg protein (determined by LAL method).
101.4kD
50 µg/$395; 500 µg/$1,262; 1 mg/$1,627; 10 µg/$277
HEK 293 Cells
None
Biologically active
Less than 0.1 ng/µg of protein (less than 1EU/µg).
74.0 kDa
10 µg/$268; 50 µg/$349
E. coli
His
50 µg/$411; 250 µg/$985; 10 µg/$276
HEK 293 Cells
Myc-DDK (Flag)
68.7 kDa
20 µg/$1,107
Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
E. coli
His
24.8 kDa
10 µg/$259; 50 µg/$331; 100 µg/$482; 200 µg/$602; 1 mg/$1,553; 500 µg/$1,156; 5 mg/$2,481; 2 mg/$1,723
E. coli
His
20.3 kDa
10 µg/$278; 50 µg/$422; 100 µg/$672; 200 µg/$842; 1 mg/$1,934; 500 µg/$1,480; 5 mg/$2,941; 2 mg/$2,119
E. coli
His-T7
13.2 kDa
10 µg/$288; 50 µg/$487; 100 µg/$780; 200 µg/$972; 1 mg/$2,109; 500 µg/$1,636; 5 mg/$3,403; 2 mg/$2,298
E. coli
His-S
36.0 kDa
10 µg/$271; 50 µg/$382; 100 µg/$610; 200 µg/$762; 1 mg/$1,817; 500 µg/$1,378; 5 mg/$2,775; 2 mg/$1,998
E. coli
His
23.1 kDa
10 µg/$278; 50 µg/$422; 100 µg/$672; 200 µg/$842; 1 mg/$1,934; 500 µg/$1,480; 5 mg/$2,941; 2 mg/$2,119
E. coli
His-T7
35.8 kDa
10 µg/$286; 50 µg/$472; 100 µg/$752; 200 µg/$942; 1 mg/$2,069; 500 µg/$1,600; 5 mg/$3,291; 2 mg/$2,257
E. coli
His-SUMO
90.2 kD
1 mg/$1,355; 100 µg/$420; 20 µg/$323
Wheat Germ Extract
GST
106.81 kDa
10 µg/$479; 25 µg/$670
Human Cells
His
Less than 1.0 EU/µg protein (determined by LAL method).
75.8 kDa
100 µg/$661; 1 mg/$3,499
293T Cells
Myc-DDK (Flag)
81.28 kDa
20 µg/$150
HEK 293 Cells
Myc-DDK (Flag)
81.28 kDa
100 µg/$494
CHO Cells
None
Biologically active
Less than 0.1 ng/µg of protein (less than 1EU/µg).
74.4 kDa
10 µg/$268; 50 µg/$349
Yeast
6His, N-terminus
100 µg/$446; 20 µg/$336; 1 mg/$1,460
HEK 293 Cells
None
Biologically active
Less than 0.01 ng/µg (determined by LAL method).
The 914 amino acid recombinant protein with a C-terminal human IgG1 Fc tag has a predicted molecular mass of approximately 101.4 kD. The protein migrates at approximately 130 kD by SDS-PAGE in DTT-reducing conditions and approximately 260 kD in non-reduci
25 µg/$306; 100 µg/$436
Mammalian Cells
Fc, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
101.4 kDa
10 µg/$277; 50 µg/$389
Mammalian Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
75.3 kDa
10 µg/$248; 50 µg/$317
Human Cells
Fc
Less than 1.0 EU/µg protein (determined by LAL method).
101 kDa
100 µg/$502
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of 27
product results
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