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TPO / Thyroid Peroxidase
thyroid peroxidase
TPO / Thyroid Peroxidase is a membrane-bound glycoprotein. The encoded protein acts as an enzyme and plays a central role in thyroid gland function. The protein functions in the iodination of tyrosine residues in thyroglobulin and phenoxy-ester formation between pairs of iodinated tyrosines to generate the thyroid hormones, thyroxine and triiodothyronine. Mutations in this gene are associated with several disorders of thyroid hormonogenesis, including congenital hypothyroidism, congenital goiter, and thyroid hormone organification defect IIA. Multiple transcript variants encoding distinct isoforms have been identified for this gene, but the full-length nature of some variants has not been determined.
| Gene Name: | thyroid peroxidase |
| Synonyms: | TPO, MSA, Thyroid microsomal antigen, Thyroid peroxidase, TDH2A, TPX, Thyroperoxidase |
| Target Sequences: | NM_000547 NP_000538.3 P07202 |
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(24)
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Custom
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(87)
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(11)
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(16)
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Target
TPO / Thyroid Peroxidase
(124)
Reactivity
Human
(72)
Mouse
(24)
Rat
(24)
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(1)
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(3)
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(1)
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(35)
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(1)
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monoclonal mc
(42)
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(45)
Clone
05
(1)
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17
(1)
23
(1)
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(1)
313
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TS106
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(13)
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(3)
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(3)
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(11)
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(11)
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(8)
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(7)
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(31)
Epitope
aa107-276
(8)
aa39-217
(8)
aa636-832
(8)
aa167-216
(4)
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(4)
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(1)
aa850-C-term
(1)
Publications
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(124)
Sample Type
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(2)
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(3)
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(17)
Serum
(16)
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(9)
Tag
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(1)
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(1)
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(6)
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(1)
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(3)
Species
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(9)
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(2)
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(1)
Source
293T Cells
(1)
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(1)
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(4)
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(3)
Insect Cells
(1)
Wheat Germ Extract
(2)
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(1)
Purification
Purified
(1)
Low Endotoxin Level
Low endotoxin level
(2)
Sandwich
96-Well Strip Plate
Monkey
31.25 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$656
Insect Cells
None
100-110 kDa
100 µg/$1,380
E. coli
His
21.5 kDa
10 µg/$278; 50 µg/$422; 100 µg/$672; 200 µg/$842; 1 mg/$1,934; 500 µg/$1,480; 5 mg/$2,941; 2 mg/$2,119
TPO / Thyroid Peroxidase Mouse anti-Human Monoclonal (MoAb47) Antibody
Human
IHC, IHC-P
Unconjugated
0.1 ml/$313; 0.5 ml/$631; 1 ml/$987
TPO / Thyroid Peroxidase Mouse anti-Human Monoclonal (6H7) Antibody
Human
ELISA, WB
Unconjugated
0.2 mg/$486
TPO / Thyroid Peroxidase Rabbit anti-Mouse Polyclonal (aa636-832) (APC) Antibody
Mouse, Rat
WB
APC Conjugated
100 µl/$392; 200 µl/$470; 500 µl/$798; 1 ml/$951; 2 ml/$1,211; 5 ml/$2,269
TPO / Thyroid Peroxidase Rabbit anti-Human Polyclonal (aa19-846) (HRP) Antibody
Human
ELISA
HRP Conjugated
50 µg/$294; 100 µg/$360
TPO / Thyroid Peroxidase Rabbit anti-Human Polyclonal (Preservative Free) Antibody
Human
ELISA, ICC, IF, IHC-P, WB
Unconjugated, Preservative Free
100 µl/$412
Cancer
TPO / Thyroid Peroxidase Goat anti-Human Polyclonal (aa850-C-term) Antibody
Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
100 µg/$485
Competitive EIA
96-Well Strip Plate
Rat
2.5 - 40 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$822
Cancer
TPO / Thyroid Peroxidase Mouse anti-Human Monoclonal Antibody
Human
IHC, IHC-P
Unconjugated
100 µl/$460
TPO / Thyroid Peroxidase Rabbit anti-Human Monoclonal (Preservative Free) (313) Antibody
Human
ELISA
Unconjugated, Preservative Free
100 µl/$412
Sandwich
96-Well Strip Plate
Pig
15.6 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Tissue Homogenates
1 Plate/$669
E. coli
His
23.9 kDa
10 µg/$278; 50 µg/$422; 100 µg/$672; 200 µg/$842; 1 mg/$1,934; 500 µg/$1,480; 5 mg/$2,941; 2 mg/$2,119
TPO / Thyroid Peroxidase Rabbit anti-Mouse Polyclonal (aa39-217) Antibody
Mouse
ICC, IP, WB
Unconjugated
100 µl/$301; 200 µl/$340; 500 µl/$470; 1 ml/$535; 2 ml/$698; 5 ml/$1,161
TPO / Thyroid Peroxidase Rabbit anti-Mouse Polyclonal (aa39-217) (HRP) Antibody
Mouse
ICC, IP, WB
HRP Conjugated
100 µl/$329; 200 µl/$379; 500 µl/$547; 1 ml/$649; 2 ml/$884; 5 ml/$1,475
TPO / Thyroid Peroxidase Rabbit anti-Mouse Polyclonal (aa39-217) (Biotin) Antibody
Mouse
ICC, IP, WB
Biotin Conjugated
100 µl/$311; 200 µl/$353; 500 µl/$496; 1 ml/$567; 2 ml/$769; 5 ml/$1,248
TPO / Thyroid Peroxidase Rabbit anti-Mouse Polyclonal (aa39-217) (FITC) Antibody
Mouse
ICC, IP, WB
FITC Conjugated
100 µl/$338; 200 µl/$392; 500 µl/$573; 1 ml/$698; 2 ml/$936; 5 ml/$1,588
TPO / Thyroid Peroxidase Rabbit anti-Mouse Polyclonal (aa39-217) (Cy3) Antibody
Mouse
ICC, IP, WB
Cy3 Conjugated
100 µl/$392; 200 µl/$470; 500 µl/$798; 1 ml/$951; 2 ml/$1,211; 5 ml/$2,269
TPO / Thyroid Peroxidase Rabbit anti-Mouse Polyclonal (aa39-217) (APC, Cy7) Antibody
Mouse
ICC, IP, WB
APC, Cy7 Conjugated
100 µl/$483; 200 µl/$599; 500 µl/$1,089; 1 ml/$1,297; 2 ml/$1,815; 5 ml/$3,403
TPO / Thyroid Peroxidase Rabbit anti-Mouse Polyclonal (aa39-217) (PE) Antibody
Mouse
ICC, IP, WB
PE Conjugated
100 µl/$392; 200 µl/$470; 500 µl/$798; 1 ml/$951; 2 ml/$1,211; 5 ml/$2,269
TPO / Thyroid Peroxidase Rabbit anti-Mouse Polyclonal (aa39-217) (APC) Antibody
Mouse
ICC, IP, WB
APC Conjugated
100 µl/$392; 200 µl/$470; 500 µl/$798; 1 ml/$951; 2 ml/$1,211; 5 ml/$2,269
TPO / Thyroid Peroxidase Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µg/$294; 100 µg/$360
TPO / Thyroid Peroxidase Goat anti-Human Polyclonal (aa209-223) Antibody
Human
IHC, Peptide-ELISA, WB
Unconjugated
100 µg/$503
TPO / Thyroid Peroxidase Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
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