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Vector Laboratories, Inc.
6737 Mowry Ave
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TNF Alpha
tumor necrosis factor
TNF Alpha is a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer. Knockout studies in mice also suggested the neuroprotective function of this cytokine.
| Gene Name: | tumor necrosis factor |
| Family/Subfamily: | TNF , not assigned-TNF |
| Synonyms: | TNF, APC1 protein, Cachectin, DIF, TNF Alpha, Tumor necrosis factor-alpha, TNF-alpha, TNF-a, TNFA, Tumor necrosis factor, TNF, macrophage-derived, TNF, monocyte-derived, TNFSF2 |
| Target Sequences: | NM_000594 NP_000585.2 P01375 |
Publications (20)
1
Down-regulation of tumor necrosis factor alpha expression by activating transcription factor 2 increases UVC-induced apoptosis of late-stage melanoma cells. Ivanov VN, Ronai Z. The Journal of biological chemistry. 1999 274:14079-89.
[PubMed:10318823]
Related Antibodies: LS-C41024.
2
TNF-alpha drives human CD14+ monocytes to differentiate into CD70+ dendritic cells evoking Th1 and Th17 responses. Iwamoto S, Iwai S, Tsujiyama K, Kurahashi C, Takeshita K, Naoe M, Masunaga A, Ogawa Y, Oguchi K, Miyazaki A. Journal of immunology (Baltimore, Md. : 1950). 2007 179:1449-57.
[PubMed:17641010]
Related Antibodies: LS-C41025.
3
Rapid, efficient functional characterization and recovery of HIV-specific human CD8+ T cells using microengraving. Varadarajan N, Kwon DS, Law KM, Ogunniyi AO, Anahtar MN, Richter JM, Walker BD, Love JC. Proceedings of the National Academy of Sciences of the United States of America. 2012 109:3885-90.
[PubMed:22355106]
[PMC:PMC3309713]
Related Antibodies: LS-C41024.
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TNF Alpha Mouse anti-Human Monoclonal (M 1 C4) Antibody
Rat, Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$440
TNF Alpha Mouse anti-Human Monoclonal (2C8) Antibody
Human
IHC, IHC-P
Unconjugated
0.25 mg/$575
TNF Alpha Mouse anti-Human Monoclonal (52B83) Antibody
Mouse, Guinea pig, Human, Monkey
ELISA, Flo, IHC, IHC-Fr, IHC-P, WB
Unconjugated
50 µg/$485
TNF Alpha Rabbit anti-Mouse Polyclonal Antibody
Mouse
ELISA, IHC, IP, Neut, RIA, WB
Unconjugated
1 mg/$1,225
TNF Alpha Mouse anti-Human Monoclonal (MAb1) Antibody
Human, Monkey
ELISA, WB
Unconjugated
50 µg/$264
TNF Alpha Rabbit anti-Bovine Polyclonal (Preservative Free) Antibody
Bovine
ELISA, WB
Unconjugated, Preservative Free
0.5 mg/$663
TNF Alpha Rabbit anti-Human Polyclonal (aa100-200) Antibody
Mouse, Rat, Human
ICC, IF, IHC, IHC-P, WB
Unconjugated
0.1 mg/$386
TNF Alpha Rabbit anti-Human Polyclonal (Internal) Antibody
Mouse, Rat, Human, Monkey
IHC, IHC-P, WB
Unconjugated
100 µl/$299
TNF Alpha Rat anti-Mouse Monoclonal (V1q) Antibody
Mouse, Hamster
Flo, Func
Unconjugated
100 µg/$589
TNF Alpha Rabbit anti-Human Polyclonal Antibody
Human, Monkey, Cynomolgus
ELISA, WB
Unconjugated
500 µl/$720; 1 ml/$1,027
TNF Alpha Rabbit anti-Rat Polyclonal Antibody
Rat
ELISA, WB
Unconjugated
50 µg/$356; 100 µg/$396
TNF Alpha Mouse anti-Human Monoclonal (4H31) Antibody
Human, Monkey, Cynomolgus
Flo, Func, IHC, IHC-Fr, IP, WB
Unconjugated
100 µg/$516
TNF Alpha Mouse anti-Human Monoclonal (MAb11) Antibody
Pig, Human, Monkey, Baboon
Flo, IHC, IHC-Fr
Unconjugated
50 µg/$264
TNF Alpha Mouse anti-Human Monoclonal Antibody
Human
ELISA, WB
Unconjugated
500 µg/$326
E. coli
None
Biologically active
Less than 0.1 ng/µg of protein (less than 1EU/µg).
17.4 kDa
10 µg/$268; 50 µg/$349
Sandwich
96-Well Microplate
Rat
15.6 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$559
Sandwich
96-Well Microplate
Human
15.6 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$559
Sandwich
96-Well Microplate
Mouse
15.6 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum
1 Plate/$559
Sandwich
96-Well Strip Plate
Bovine
7.8 - 500 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$806
Sandwich
96-Well Strip Plate
Rabbit
3.12 - 200 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$651
Sandwich
96-Well Strip Plate
Mouse
15.6 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$617
Sandwich
96-Well Strip Plate
Rat
15.6 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$651
Sandwich
96-Well Strip Plate
Guinea pig
7.8 - 500 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$685
Sandwich
96-Well Strip Plate
Human
1.56 - 100 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$722
Sandwich
96-Well Strip Plate
Dog
12.5 - 800 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$669
Viewing 1-25
of 680
product results
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