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TJP2 / ZO2 / ZO-2
tight junction protein 2
TJP2 / ZO2 / ZO-2 is a zonula occluden that is a member of the membrane-associated guanylate kinase homolog family. The encoded protein functions as a component of the tight junction barrier in epithelial and endothelial cells and is necessary for proper assembly of tight junctions. Mutations in this gene have been identified in patients with hypercholanemia, and genomic duplication of a 270 kb region including this gene causes autosomal dominant deafness-51. Alternatively spliced transcripts encoding multiple isoforms have been observed for this gene.
| Gene Name: | tight junction protein 2 |
| Family/Subfamily: | Occludin , not assigned-Occludin |
| Synonyms: | TJP2, C9DUPq21.11, DUP9q21.11, DFNA51, ZO-2, Zona occludens 2, Zonula occludens protein 2, Tight junction protein 2, Tight junction protein ZO-2, ZO2, X104, Zona occludens protein 2 |
| Target Sequences: | NM_004817 NP_004808.2 Q9UDY2 |
Publications (4)
1
Persistent Marburg Virus Infection in the Testes of Nonhuman Primate Survivors. Kayla M Coffin, Jun Liu, Travis K Warren, Candace D Blancett, Kathleen A Kuehl, Donald K Nichols, Jeremy J Bearss, Christopher W Schellhase, Cary J Retterer, Jessica M Weidner, Sheli R Radoshitzky, Jennifer M Brannan, Anthony P Cardile, John M Dye, Gustavo Palacios, Mei G Sun, Jens H Kuhn, Sina Bavari, Xiankun Zeng. Cell host & microbe. 2018 September;24:405-416.e3. [Full Text Article]
[PubMed:30173956]
Related Antibodies: LS-C313092.
2
TJP2 hepatobiliary disorders: Novel variants and clinical diversity. Jing Zhang, Lang-Li Liu, Jing-Yu Gong, Chen-Zhi Hao, Yi-Ling Qiu, Yi Lu, Jia-Yan Feng, Jia-Qi Li, Zhong-Die Li, Meng-Xuan Wang, Qing-He Xing, A S Knisely, Jian-She Wang. Human mutation. 2020 Feburary;41:502-511. [Full Text Article]
[PubMed:31696999]
Related Antibodies: LS-B2185.
3
Low-GGT intrahepatic cholestasis associated with biallelic USP53 variants: Clinical, histological and ultrastructural characterization. Jing Zhang, Ye Yang, Jing-Yu Gong, Li-Ting Li, Jia-Qi Li, Mei-Hong Zhang, Yi Lu, Xin-Bao Xie, Yu-Ren Hong, Zhang Yu, A S Knisely, Jian-She Wang. Liver international : official journal of the International Association for the Study of the Liver. 2020 May;40:1142-1150. [Full Text Article]
[PubMed:32124521]
Related Antibodies: LS-B2185.
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TJP2 / ZO2 / ZO-2 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Mouse, Dog, Rat, Human
IF, IHC, IHC-P, WB
Unconjugated
50 µg/$485
TJP2 / ZO2 / ZO-2 Rabbit anti-Human Polyclonal (HRP) Antibody
Mouse, Dog, Rat, Human
IF, WB
HRP Conjugated
100 µl/$1,023
TJP2 / ZO2 / ZO-2 Rabbit anti-Human Polyclonal (FITC) Antibody
Mouse, Dog, Rat, Human
IF, WB
FITC Conjugated
100 µl/$1,023
TJP2 / ZO2 / ZO-2 Rabbit anti-Human Polyclonal (APC) Antibody
Mouse, Dog, Rat, Human
IF, WB
APC Conjugated
100 µl/$1,023
TJP2 / ZO2 / ZO-2 Rabbit anti-Human Polyclonal (PE) Antibody
Mouse, Dog, Rat, Human
IF, WB
PE Conjugated
100 µl/$1,023
TJP2 / ZO2 / ZO-2 Rabbit anti-Human Polyclonal (aa1171-1190) Antibody
Human, Monkey
IHC, IHC-Fr, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
TJP2 / ZO2 / ZO-2 Mouse anti-Human Monoclonal (Internal) Antibody
Dog, Human
ELISA, IF, IP, WB
Unconjugated
100 µg/$795
TJP2 / ZO2 / ZO-2 Mouse anti-Human Monoclonal (HRP) Antibody
Dog, Human
ELISA, IF, IP, WB
HRP Conjugated
100 µl/$1,023
TJP2 / ZO2 / ZO-2 Mouse anti-Human Monoclonal (Biotin) Antibody
Dog, Human
ELISA, IF, IP, WB
Biotin Conjugated
100 µl/$1,023
TJP2 / ZO2 / ZO-2 Mouse anti-Human Monoclonal (FITC) Antibody
Dog, Human
ELISA, IF, IP, WB
FITC Conjugated
100 µl/$1,023
TJP2 / ZO2 / ZO-2 Mouse anti-Human Monoclonal (APC) Antibody
Dog, Human
ELISA, IF, IP, WB
APC Conjugated
100 µl/$1,023
TJP2 / ZO2 / ZO-2 Mouse anti-Human Monoclonal (PE) Antibody
Dog, Human
ELISA, IF, IP, WB
PE Conjugated
100 µl/$1,023
Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Tissue Homogenates
1 Plate/$730
TJP2 / ZO2 / ZO-2 Rabbit anti-Mouse Polyclonal (aa1149-1167) Antibody
Mouse, Rat
IHC, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
TJP2 / ZO2 / ZO-2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
TJP2 / ZO2 / ZO-2 Guinea pig anti-Human Polyclonal (aa411-467) Antibody
Mouse, Human
IF, IHC, IHC-Fr, WB
Unconjugated
100 µg/$862
TJP2 / ZO2 / ZO-2 Guinea pig anti-Human Polyclonal (aa411-467) Antibody
Mouse, Human
IF, IHC, IHC-Fr, WB
Unconjugated
100 µg/$589
293T Cells
Myc-DDK (Flag)
133.8 kDa
20 µg/$150
TJP2 / ZO2 / ZO-2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, WB
Unconjugated
100 µg/$341
TJP2 / ZO2 / ZO-2 Rabbit anti-Dog Polyclonal Antibody
Mouse, Dog, Human
ELISA, IHC, WB
Unconjugated
100 µg/$801
TJP2 / ZO2 / ZO-2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
TJP2 / ZO2 / ZO-2 Rabbit anti-Human Polyclonal (aa740-790) Antibody
Human
IHC
Unconjugated
100 µl/$393
TJP2 / ZO2 / ZO-2 Rabbit anti-Human Polyclonal (pTyr1118) Antibody
Mouse, Rat, Human
ELISA, Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
TJP2 / ZO2 / ZO-2 Rabbit anti-Human Polyclonal (aa981-1009) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
TJP2 / ZO2 / ZO-2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
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