TERT / Telomerase

telomerase reverse transcriptase

Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nucleotide telomeric repeat unit, 5'-TTAGGG-3'. The catalytic cycle involves primer binding, primer extension and release of product once the template boundary has been reached or nascent product translocation followed by further extension. More active on substrates containing 2 or 3 telomeric repeats. Telomerase activity is regulated by a number of factors including telomerase complex-associated proteins, chaperones and polypeptide modifiers. Modulates Wnt signaling. Plays important roles in aging and antiapoptosis.

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Products

Antibodies (92)

ELISA Kits (33)

Proteins (6)

Type

Cell-Based (1)

Cell-Based Phosphorylation (1)

Competitive EIA (2)

Custom (1)

Over-Expression Lysate (1)

Primary (92)

Recombinant (5)

Sandwich (26)

Sandwich CLIA (2)

Target

TERT / Telomerase (131)

Reactivity

Human (78)

Mouse (19)

Rat (18)

Bovine (1)

Chicken (2)

Dog (1)

Guinea pig (2)

Hydra vulgaris (4)

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Host

rabbit (81)

mouse (4)

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Yes (2)

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Cell Lysates (1)

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Species

Human (2)

Mouse (2)

Rat (1)

Source

E. coli (5)

HEK 293 Cells (1)

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Purified (2)

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IHC-plus™ TERT / Telomerase Antibody (aa627-656) LS-B11086

(5.0) Rating

(1) Publication(s)

Antibody:

TERT / Telomerase Rabbit anti-Human Polyclonal (aa627-656) Antibody

Reactivity:

Human

Applications:

Flo, IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

200 µl/$460

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IHC-plus™ TERT / Telomerase Antibody (clone 2D8) LS-B95

(5.0) Rating

(2) Publication(s)

Antibody:

TERT / Telomerase Mouse anti-Human Monoclonal (2D8) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P

Format:

Unconjugated

Price:

0.1 ml/$460

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IHC-plus™ TERT / Telomerase Antibody LS-A12147

Fast Shipping

(4.0) Rating

Antibody:

TERT / Telomerase Rabbit anti-Human Polyclonal Antibody

Applications:

IHC-P

Format:

Unconjugated

Price:

50 µg/$460

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TERT / Telomerase Antibody (phospho-Ser824) LS-C368547

Antibody:

TERT / Telomerase Rabbit anti-Human Polyclonal (pSer824) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

30 µl/$263; 100 µl/$315; 200 µl/$379

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TERT / Telomerase Antibody LS-C10505

Antibody:

TERT / Telomerase Rabbit anti-Mouse Polyclonal Antibody

Reactivity:

Mouse

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$832

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TERT / Telomerase Antibody (aa597-611) LS-C154896

Antibody:

TERT / Telomerase Goat anti-Human Polyclonal (aa597-611) Antibody

Reactivity:

Human

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µg/$503

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Human TERT / Telomerase (Cell-Based ELISA) ELISA Kit - LS-F2346

Type:

Cell-Based

Format:

96-Well Microplate

Reactivity:

Human

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Adherent Cell Cultures

Price:

1 Plate/$534

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Human TERT / Telomerase (Sandwich ELISA) ELISA Kit - LS-F7351

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

15.6 - 1000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Tissue Homogenates

Price:

1 Plate/$730

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Human TERT / Telomerase (Sandwich ELISA) ELISA Kit - LS-F12713

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$669

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Human TERT / Telomerase Protein (Recombinant His-GST) (aa787-1084) - LS-G14856

Source:

E. coli

Tag:

His-GST

Molecular Weight:

65.8 kDa

Price:

10 µg/$276; 50 µg/$412; 100 µg/$657; 200 µg/$822; 1 mg/$1,905; 500 µg/$1,455; 5 mg/$2,871; 2 mg/$2,090

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Mouse TERT / Telomerase (Sandwich ELISA) ELISA Kit - LS-F34958

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

0.313 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

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TERT / Telomerase Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G102557

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

126.8 kDa

Price:

100 µg/$710

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Human TERT / Telomerase Protein (Recombinant 6His, N-terminus) (aa281-436) - LS-G56567

Source:

E. coli

Tag:

6His, N-terminus

Price:

1 mg/$1,486; 100 µg/$451; 20 µg/$339

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Mouse TERT / Telomerase (Sandwich ELISA) ELISA Kit - LS-F12716

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

0.312 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$669

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TERT / Telomerase Antibody (aa196-245) LS-C118018

Antibody:

TERT / Telomerase Rabbit anti-Human Polyclonal (aa196-245) Antibody

Reactivity:

Human

Applications:

IF, Peptide-ELISA

Format:

Unconjugated

Price:

50 µl/$334; 100 µl/$397

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TERT / Telomerase Antibody (N-Terminus) LS-C10515

Antibody:

TERT / Telomerase Rabbit anti-Yeast Polyclonal (N-Terminus) Antibody

Reactivity:

Yeast

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$832

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TERT / Telomerase Antibody (aa796-845) LS-C118019

Antibody:

TERT / Telomerase Rabbit anti-Human Polyclonal (aa796-845) Antibody

Reactivity:

Human

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µl/$334; 100 µl/$397

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TERT / Telomerase Antibody (aa642-974) LS-C296590

Antibody:

TERT / Telomerase Rabbit anti-Mouse Polyclonal (aa642-974) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$311; 200 µl/$355; 500 µl/$499; 1 ml/$571; 2 ml/$777; 5 ml/$1,261

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Dog TERT / Telomerase (Sandwich ELISA) ELISA Kit - LS-F12715

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Dog

Range:

78 - 5000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$783

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TERT / Telomerase Antibody LS-C402387

Antibody:

TERT / Telomerase Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

Unconjugated

Price:

20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450

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TERT / Telomerase Antibody (Internal) LS-C10506

Antibody:

TERT / Telomerase Rabbit anti-Mouse Polyclonal (Internal) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µl/$801

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TERT / Telomerase Antibody (phospho-Tyr707) LS-C100313

Antibody:

TERT / Telomerase Rabbit anti-Human Polyclonal (pTyr707) Antibody

Reactivity:

Human

Applications:

DB, IF

Format:

Unconjugated

Price:

400 µl/$393

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TERT / Telomerase Antibody (phospho-Ser824) LS-C191890

Antibody:

TERT / Telomerase Rabbit anti-Human Polyclonal (pSer824) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

50 µl/$328; 100 µl/$419

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TERT / Telomerase Antibody (Internal) LS-C413209

Antibody:

TERT / Telomerase Rabbit anti-Human Polyclonal (Internal) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$321

Select

Rat TERT / Telomerase (Sandwich ELISA) ELISA Kit - LS-F9171

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

31.25 - 2000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$783

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