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CD47

CD47 molecule

Has a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. Plays an important role in memory formation and synaptic plasticity in the hippocampus (By similarity). Receptor for SIRPA, binding to which prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. Interaction with SIRPG mediates cell-cell adhesion, enhances superantigen-dependent T-cell-mediated proliferation and costimulates T-cell activation. May play a role in membrane transport and/or integrin dependent signal transduction. May prevent premature elimination of red blood cells. May be involved in membrane permeability changes induced following virus infection.

Gene Name: CD47 molecule
Synonyms: CD47, CD47 antigen, CD47 molecule, Integrin associated protein, Integrin-associated protein, Leukocyte surface antigen CD47, MER6, Protein MER6, Rh-related antigen, OA3, CD47 glycoprotein, IAP
Target Sequences: NM_001777 NP_001768.1 Q08722

Publications (3)

1
CD47 is an adverse prognostic factor and a therapeutic target in gastric cancer. Yoshida K, Tsujimoto H, Matsumura K, Kinoshita M, Takahata R, Matsumoto Y, Hiraki S, Ono S, Seki S, Yamamoto J, Hase K. Cancer medicine. 2015 4:1322-33. (IP; Human) [Full Text Article] [PubMed:26077800] [PMC:PMC4567017]
2
Expression of CD47 antigen in Reed-Sternberg cells as a new potential biomarker for classical Hodgkin lymphoma. B López-Pereira, A A Fernández-Velasco, I Fernández-Vega, D Corte-Torres, C Quirós, J A Villegas, P Palomo, S González, A P González, Á Payer, T Bernal, M A Moro-García, R Alonso-Arias, S Alonso-Álvarez, E Colado. Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico. 2020 May;22:782-785. [Full Text Article] [PubMed:31359339]
3
Checkpoint CD47 expression in classical Hodgkin lymphoma. Alex Reza Gholiha, Peter Hollander, Liza Löf, Ingrid Glimelius, Gustaf Hedstrom, Daniel Molin, Henrik Hjalgrim, Karin E Smedby, Jamileh Hashemi, Rose-Marie Amini, Gunilla Enblad. British journal of haematology. 2022 June;197:580-589. [Full Text Article] [PubMed:35301709] [PMC:PMC9310712]

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Antibodies (131)
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CD47 (181)
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CD47 Antibody - Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE)
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CD47 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat
IF, IHC, IHC-P, WB
Unconjugated
50 µl/$460
CD47 Antibody - Anti-CD47 antibody IHC staining of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.
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CD47 Rabbit anti-Human Polyclonal (aa288-315) Antibody
Human
IHC, IHC-P, WB
Unconjugated
200 µl/$460
CD47 Antibody - Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE)
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CD47 Rabbit anti-Human Polyclonal (aa23-140) Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µg/$460
CD47 Antibody - IHC staining of FFPE human tonsil tissue with CD47 antibody at 1ug/ml. HIER: boil tissue sections in pH6, 10mM citrate buffer, for 10-20 min and allow to cool before testing.
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CD47 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, Flo, IF, IHC-P, WB
Unconjugated
100 µg/$575
CD47 Antibody - Cell surface flow cytometry of CD47 on human peripheral blood lymphocytes using 0.5 ug/0.5x10^6 cells of Monoclonal Antibody to human CD47 (Clone B6H12.2) Azide-free. Green histogram represents isotype control ( This image was taken for the unmodified form of this product. Other forms have not been tested.
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CD47 Mouse anti-Human Monoclonal (Azide-free) (B6H12.2) Antibody
Human
Flo
Unconjugated, Azide-free
100 µg/$386
CD47 Antibody - Flow cytometric analysis of Human CD47 expression on human whole blood lymphocytes. Cells were stained with purified anti-Human CD47, then a FITC-conjugated second step antibody. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of viable lymphocytes.
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CD47 Mouse anti-Human Monoclonal (Preservative Free) (07) Antibody
Human
Flo
Unconjugated, Preservative Free
100 µl/$412
CD47 Antibody - Western blot of recombinant CD47.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CD47 Rabbit anti-Mouse Polyclonal (aa18-219) Antibody
Mouse
WB
Unconjugated
100 µl/$306; 200 µl/$347; 500 µl/$484; 1 ml/$553; 2 ml/$737; 5 ml/$1,206
CD47 ELISA Kit
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Sandwich
96-Well Strip Plate
Human
125 - 8000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Serum
1 Plate/$624
CD47 ELISA Kit
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Sandwich
96-Well Strip Plate
Mouse
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$748
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CD47 Mouse anti-Human Monoclonal (Azide-free, Low Endotoxin) (MIAP410) Antibody
Mouse, Rat, Human
Flo, ICC, IF, IHC, IP, WB
Unconjugated, Azide-free, Low Endotoxin
50 µg/$248; 500 µg/$333; 1 mg/$433
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CD47 Mouse anti-Human Monoclonal (IAP/964 + B6H12.2) Antibody
Mouse, Human
Flo, IF, IHC, IHC-P
Unconjugated
20 µg/$371; 100 µg/$574
CD47 Protein - Recombinant Integrin Associated Protein By SDS-PAGE
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E. coli
6His, N-terminus
23.9 kDa
10 µg/$267; 50 µg/$352; 100 µg/$562; 200 µg/$702; 1 mg/$1,723; 500 µg/$1,298; 5 mg/$2,673; 2 mg/$1,900
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CD47 Mouse anti-Human Monoclonal (BRIC126) Antibody
Human
Flo, IHC, IHC-Fr, IP, WB
Unconjugated
25 µg/$281; 0.2 mg/$471
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CD47 Mouse anti-Human Monoclonal (1/1A4) Antibody
Human
Flo, IHC, IHC-Fr, IP
Unconjugated
0.1 mg/$385; 0.2 mg/$471
CD47 Antibody - Surface staining of lysed and washed porcine peripheral blood with purified anti-CD47 (MEM-122) (detection by anti-mouse IgM FITC).  Panel A - porcine PBMC stained with Isotype mouse IgM control (PFR-03)  Panel B, C, D - porcine PBMC sample stained with anti-CD47 (MEM-122)  Cells in the granulocyte gate were used for analysis.
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CD47 Mouse anti-Monkey Monoclonal (MEM-122) Antibody
Porcine, Non-Human Primates, Human
Flo, IHC, IHC-Fr, WB
Unconjugated
0.1 mg/$309
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CD47 Mouse anti-Human Monoclonal (B6H12) Antibody
Human
Flo
Unconjugated
100 µl/$434
CD47 Antibody - C57BL/6 murine splenocytes are stained with Anti-Human/Mouse/Rat CD47 Monoclonal Antibody(AF488 Conjugated)(filled gray histogram). Unstained splenocytes (empty black histogram) are used as control.
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CD47 Mouse anti-Human Monoclonal (AF488) (MIAP410) Antibody
Mouse, Rat, Human
Flo
AF488 Conjugated
20 Tests/$268; 100 Tests/$353; 200 Tests/$423
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CD47 Mouse anti-Human Monoclonal (Low Endotoxin) (1/1A4) Antibody
Human
Flo, IHC, IHC-Fr, IP
Unconjugated, Low Endotoxin
0.5 mg/$671
CD47 Antibody - Fig-1: Cell Surface flow analysis of hCD47 in PBMC (Lymphocytes) using 0.5 µg/10^6 cells. Green represents isotype control; red represents FITC conjugated anti-hCD47 antibody (F).
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CD47 Mouse anti-Human Monoclonal (FITC) (B6H12) Antibody
Human
Flo
FITC Conjugated
25 µg/$288; 100 µg/$414
CD47 Antibody
Select
CD47 Mouse anti-Human Monoclonal (AF488) (CC2C6D4) Antibody
Human
Flo
AF488 Conjugated
20 Tests/$256; 100 Tests/$306; 200 Tests/$353
CD47 Antibody - Immunochemical staining CD47 in cynomolgus urinary bladder with rabbit polyclonal antibody at 1:1000 dilution, formalin-fixed paraffin embedded sections.
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CD47 Rabbit anti-Human Polyclonal Antibody
Human, Crab-eating macaque
ELISA, ICC, IF, IHC-P
Unconjugated
20 µl/$256; 100 µl/$412
CD47 Antibody - Flow cytometric analysis of Human CD47 expression on human whole blood lymphocytes. Cells were stained with PE-conjugated anti-Human CD47. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of viable lymphocytes.
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CD47 Mouse anti-Human Monoclonal (PE) (07) Antibody
Human
Flo
PE Conjugated
25 Tests/$278; 100 Tests/$376
CD47 Antibody - Western blot testing of human brain lysate with CD47 antibody (clone B6H12.2). Predicted molecular weight ~35kDa but observed at 35-60kDa depending on glycosylation level.
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CD47 Mouse anti-Human Monoclonal (B6H12.2) Antibody
Human
Block, Flo, Func, IF, IHC, IHC-P, WB
Unconjugated
20 µg/$371; 100 µg/$574
Select
CD47 Rabbit anti-Human Monoclonal (Preservative Free) (006) Antibody
Human
ELISA
Unconjugated, Preservative Free
100 µl/$412
Select
CD47 Mouse anti-Human Monoclonal (IAP/964) Antibody
Mouse, Human
Flo, IF, IHC, IHC-P
Unconjugated
20 µg/$371; 100 µg/$574
Viewing 1-25 of 181 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).