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WRNIP1 / WHIP

Werner helicase interacting protein 1

Werner's syndrome is a rare autosomal recessive disorder characterized by accelerated aging that is caused by defects in the Werner syndrome ATP-dependent helicase gene (WRN). The protein encoded by this gene interacts with the exonuclease-containing N-terminal portion of the Werner protein. This protein has a ubiquitin-binding zinc-finger domain in the N-terminus, an ATPase domain, and two leucine zipper motifs in the C-terminus. It has sequence similarity to replication factor C family proteins and is conserved from E. coli to human. This protein likely accumulates at sites of DNA damage by interacting with polyubiquinated proteins and also binds to DNA polymerase delta and increases the initiation frequency of DNA polymerase delta-mediated DNA synthesis. This protein also interacts with nucleoporins at nuclear pore complexes. Two transcript variants encoding different isoforms have been isolated for this gene.

Gene Name: Werner helicase interacting protein 1
Synonyms: WRNIP1, Putative helicase RUVBL, WHIP, RP11-420G6.2, ATPase WRNIP1, BA420G6.2
Target Sequences: NM_020135 NP_064520.2 Q96S55

☰ Filters
Antibodies (18)
Proteins (5)
Over-Expression Lysate (4)
Primary (18)
Recombinant (1)
WRNIP1 / WHIP (23)
Human (18)
Mouse (6)
Rat (5)
Bat (4)
Bovine (3)
Chimpanzee (3)
Dog (1)
Gibbon (3)
Hamster (4)
Horse (1)
Monkey (5)
Pig (1)
IHC (7)
IHC-P (6)
WB (16)
ELISA (7)
IF (1)
IP (1)
Peptide-ELISA (1)
rabbit (17)
goat (1)
Product Group
IHCPlus (2)
IgG (12)
polyclonal pc (18)
APC Conjugated (1)
Azide-free (1)
Biotin Conjugated (2)
FITC Conjugated (2)
HRP Conjugated (2)
PE Conjugated (1)
Unconjugated (10)
aa1-30 (7)
aa67-116 (4)
aa400-450 (2)
aa652-665 (1)
No (23)
Myc-DDK (Flag) (5)
Human (3)
293T Cells (2)
HEK 293 Cells (3)
WRNIP1 / WHIP Antibody - Anti-WRNIP1 / WHIP antibody IHC of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 3 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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WRNIP1 / WHIP Rabbit anti-Human Polyclonal (aa67-116) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$485
WRNIP1 / WHIP Antibody - Anti-WRNIP1 / WHIP antibody IHC of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 3 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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WRNIP1 / WHIP Rabbit anti-Human Polyclonal (aa67-116) (HRP) Antibody
Mouse, Bovine, Rat, Hamster, Bat, Gibbon, Chimpanzee, Human, Monkey
IHC, IHC-P, WB
HRP Conjugated
100 µl/$469
WRNIP1 / WHIP Antibody - Anti-WRNIP1 / WHIP antibody IHC of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 3 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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WRNIP1 / WHIP Rabbit anti-Human Polyclonal (aa67-116) (Biotin) Antibody
Mouse, Bovine, Rat, Hamster, Bat, Gibbon, Chimpanzee, Human, Monkey
IHC, IHC-P, WB
Biotin Conjugated
100 µl/$469
WRNIP1 / WHIP Antibody - Anti-WRNIP1 / WHIP antibody IHC of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 3 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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WRNIP1 / WHIP Rabbit anti-Human Polyclonal (aa67-116) (FITC) Antibody
Mouse, Bovine, Rat, Hamster, Bat, Gibbon, Chimpanzee, Human, Monkey
IHC, IHC-P, WB
FITC Conjugated
100 µl/$469
WRNIP1 / WHIP Antibody - Anti-WRNIP1 / WHIP antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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WRNIP1 / WHIP Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human, Monkey
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$515
WRNIP1 / WHIP Antibody - Detection of Human WRNIP1 by Immunohistochemistry. Sample: FFPE section of human breast carcinoma. Antibody: Affinity purified rabbit anti-WRNIP1 used at a dilution of 1:250.
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WRNIP1 / WHIP Rabbit anti-Human Polyclonal (aa400-450) Antibody
Mouse, Human
IF, IHC
Unconjugated
2.5 µg/$295; 100 µl/$532
WRNIP1 / WHIP Antibody - Detection of Human WRNIP1 by Immunohistochemistry. Sample: FFPE section of human ovarian carcinoma. Antibody: Affinity purified rabbit anti-WRNIP1 used at a dilution of 1:1000 (1 ug/ml). Detection: DAB.
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WRNIP1 / WHIP Rabbit anti-Human Polyclonal (aa400-450) Antibody
Human
IHC, IP, WB
Unconjugated
10 µl/$295; 100 µl/$514
Select
WRNIP1 / WHIP Rabbit anti-Human Polyclonal (aa1-30) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
Select
WRNIP1 / WHIP Rabbit anti-Human Polyclonal (aa1-30) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$952
Select
WRNIP1 / WHIP Rabbit anti-Human Polyclonal (aa1-30) (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
200 µl/$952
Select
WRNIP1 / WHIP Rabbit anti-Human Polyclonal (aa1-30) (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$952
Select
WRNIP1 / WHIP Rabbit anti-Human Polyclonal (aa1-30) (PE) Antibody
Human
ELISA, WB
PE Conjugated
200 µl/$952
Select
WRNIP1 / WHIP Rabbit anti-Human Polyclonal (aa1-30) (Azide-free) (HRP) Antibody
Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
WRNIP1 / WHIP Antibody - Goat Anti-WHIP / WRNIP1 Antibody (4µg/ml) staining of paraffin embedded Human Kidney. Steamed antigen retrieval with Tris/EDTA buffer pH 9, HRP-staining.
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WRNIP1 / WHIP Goat anti-Human Polyclonal (aa652-665) Antibody
Mouse, Dog, Rat, Hamster, Pig, Horse, Bat, Human, Monkey
IHC-P, Peptide-ELISA, WB
Unconjugated
100 µg/$503
WRNIP1 / WHIP Antibody - Western blot analysis of extracts of HeLa cells.
Select
WRNIP1 / WHIP Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
20 µl/$275; 100 µl/$389
WRNIP1 / WHIP Antibody - Sample (30 ug of whole cell lysate) A: A431 7.5% SDS PAGE WRNIP1 / WHIP antibody diluted at 1:1000
Select
WRNIP1 / WHIP Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
100 µl/$450
WRNIP1 / WHIP Antibody - WRNIP1 Antibody western blot of NCI-H292 cell line lysates (35 ug/lane). The WRNIP1 antibody detected the WRNIP1 protein (arrow).
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WRNIP1 / WHIP Rabbit anti-Human Polyclonal (aa1-30) Antibody
Human
WB
Unconjugated
400 µl/$393
Select
WRNIP1 / WHIP Rabbit anti-Human Polyclonal Antibody
Human
Unconjugated
100 µg/$341
WRNIP1 / WHIP Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
72 kDa
20 µg/$215
WRNIP1 / WHIP Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
69.3 kDa
20 µg/$150
WRNIP1 / WHIP Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
69.3 kDa
100 µg/$494
WRNIP1 / WHIP Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
72 kDa
100 µg/$710
WRNIP1 / WHIP Protein - Purified recombinant protein WRNIP1 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
Select
HEK 293 Cells
Myc-DDK (Flag)
69.3 kDa
20 µg/$1,107
Viewing 1-23 of 23 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).