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TAGLN / Transgelin / SM22
transgelin
TAGLN / Transgelin / SM22 is a transformation and shape-change sensitive actin cross-linking/gelling protein found in fibroblasts and smooth muscle. Its expression is down-regulated in many cell lines, and this down-regulation may be an early and sensitive marker for the onset of transformation. A functional role of this protein is unclear. Two transcript variants encoding the same protein have been found for this gene.
| Gene Name: | transgelin |
| Synonyms: | TAGLN, 22 kDa actin-binding protein, SMCC, TAGLN1, WS3-10, Transgelin, Transgelin variant 2, SM22, Protein WS3-10, SM22-alpha |
| Target Sequences: | NM_003186 NP_003177.2 Q01995 |
Publications (4)
1
Proteomic profiling of chronic low-frequency stimulated fast muscle. Donoghue P, Doran P, Wynne K, Pedersen K, Dunn MJ, Ohlendieck K. Proteomics. 2007 7:3417-30.
[PubMed:17708595]
Related Antibodies: LS-B2563.
2
Sphingosine 1-phosphate induces differentiation of adipose tissue-derived mesenchymal stem cells towards smooth muscle cells. Nincheri P, Luciani P, Squecco R, Donati C, Bernacchioni C, Borgognoni L, Luciani G, Benvenuti S, Francini F, Bruni P. Cellular and molecular life sciences : CMLS. 2009 66:1741-54.
[PubMed:19337690]
Related Antibodies: LS-B2563.
3
Transforming growth factor-beta1 induces transdifferentiation of myoblasts into myofibroblasts via up-regulation of sphingosine kinase-1/S1P3 axis. Cencetti F, Bernacchioni C, Nincheri P, Donati C, Bruni P. Molecular biology of the cell. 2010 21:1111-24.
[PubMed:20089836]
[PMC:PMC2836962]
Related Antibodies: LS-B2563.
☰ Filters
Products
ELISA Kits
(11)
Type
Sandwich
(10)
Sandwich CLIA
(1)
Target
TAGLN / Transgelin / SM22
(11)
Reactivity
Human
(5)
Rat
(1)
Chicken
(1)
Guinea pig
(1)
Monkey
(1)
Porcine
(1)
Rabbit
(1)
Format
12 x 8-Well Microstrips
(1)
96-Well Microplate
(1)
96-Well Strip Plate
(9)
Publications
No
(11)
Sample Type
Cell Culture Supernatants
(1)
Cell Lysates
(1)
Plasma
(6)
Serum
(6)
Tissue Homogenates
(4)
Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$730
Sandwich
96-Well Microplate
Human
6.25 - 400 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$586
Sandwich
96-Well Strip Plate
Rat
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$783
Sandwich
96-Well Strip Plate
Human
0.625 - 40 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
Sandwich CLIA
12 x 8-Well Microstrips
Human
1.25 - 80 ng/ml
Chemiluminescent
Plasma, Serum
1 Plate/$656
Sandwich
96-Well Strip Plate
Chicken
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$656
Sandwich
96-Well Strip Plate
Monkey
6.25 - 400 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$656
Sandwich
96-Well Strip Plate
Guinea pig
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$656
Sandwich
96-Well Strip Plate
Porcine
6.25 - 400 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$656
Sandwich
96-Well Strip Plate
Rabbit
0.25 - 16 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$656
Sandwich
96-Well Strip Plate
Human
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$822
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