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SORT1 / Sortilin

sortilin 1

Functions as a sorting receptor in the Golgi compartment and as a clearance receptor on the cell surface. Required for protein transport from the Golgi apparatus to the lysosomes by a pathway that is independent of the mannose-6-phosphate receptor (M6PR). Also required for protein transport from the Golgi apparatus to the endosomes. Promotes neuronal apoptosis by mediating endocytosis of the proapoptotic precursor forms of BDNF (proBDNF) and NGFB (proNGFB). Also acts as a receptor for neurotensin. May promote mineralization of the extracellular matrix during osteogenic differentiation by scavenging extracellular LPL. Probably required in adipocytes for the formation of specialized storage vesicles containing the glucose transporter SLC2A4/GLUT4 (GLUT4 storage vesicles, or GSVs). These vesicles provide a stable pool of SLC2A4 and confer increased responsiveness to insulin. May also mediate transport from the endoplasmic reticulum to the Golgi.

Gene Name: sortilin 1
Synonyms: SORT1, 100 kDa NT receptor, gp95, LDLCQ6, Glycoprotein 95, NTR3, Sortilin 1, Sortilin, Neurotensin receptor 3
Target Sequences: X98248 CAA66904.2 Q99523

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Products
Antibodies (35)
Primary (35)
SORT1 / Sortilin (35)
Human (29)
Mouse (11)
Rat (14)
Pig (8)
IHC (12)
IHC-P (3)
WB (23)
ELISA (11)
IP (1)
Peptide-ELISA (1)
rabbit (31)
mouse (3)
sheep (1)
Product Group
PathPlus Neuro (1)
IgG (20)
IgG1 (2)
IgG2a,k (1)
monoclonal mc (3)
polyclonal pc (32)
1B3 (1)
OTI3H4 (2)
APC (1)
APC Conjugated (1)
Biotin Conjugated (3)
Carrier-free (1)
Cy3 Conjugated (1)
Cy7 Conjugated (1)
FITC Conjugated (3)
HRP Conjugated (3)
PE Conjugated (1)
Preservative Free (1)
Unconjugated (22)
aa50-320 (8)
N-Terminus (4)
aa610-754 (4)
Extracellular Domain (2)
aa34-300 (2)
Cytoplasmic Domain (1)
No (34)
Yes (1)
Select
SORT1 / Sortilin Rabbit anti-Human Polyclonal (Cytoplasmic Domain) Antibody
Human
IHC, WB
Unconjugated
500 µg/$393
Select
SORT1 / Sortilin Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
ELISA
Unconjugated
100 µg/$832
Select
SORT1 / Sortilin Rabbit anti-Human Polyclonal (Extracellular Domain) Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
50 µl/$884
SORT1 / Sortilin Antibody - Immunohistochemistry of paraffin-embedded Human liver cancer using SORT1 Polyclonal Antibody at dilution of 1:35.
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SORT1 / Sortilin Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
SORT1 / Sortilin Antibody - SORT1 monoclonal antibody (M01), clone 1B3. Western Blot analysis of SORT1 expression in human spleen.
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SORT1 / Sortilin Mouse anti-Human Monoclonal (1B3) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$423
SORT1 / Sortilin Antibody - Immunohistochemistry of paraffin-embedded human kidney using SORT1 antibody at dilution of 1:100 (40x lens).
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SORT1 / Sortilin Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IHC, WB
Unconjugated
20 µl/$275; 100 µl/$389
SORT1 / Sortilin Antibody - Western blot of SORT1 / Sortilin antibody.
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SORT1 / Sortilin Rabbit anti-Human Polyclonal (aa50-320) Antibody
Pig, Human
WB
Unconjugated
100 µl/$309; 200 µl/$351; 500 µl/$491; 1 ml/$561; 2 ml/$755; 5 ml/$1,225
SORT1 / Sortilin Antibody - Western blot of SORT1 / Sortilin antibody.
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SORT1 / Sortilin Rabbit anti-Human Polyclonal (aa50-320) (HRP) Antibody
Pig, Human
WB
HRP Conjugated
100 µl/$338; 200 µl/$393; 500 µl/$575; 1 ml/$702; 2 ml/$939; 5 ml/$1,593
SORT1 / Sortilin Antibody - Western blot of SORT1 / Sortilin antibody.
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SORT1 / Sortilin Rabbit anti-Human Polyclonal (aa50-320) (Biotin) Antibody
Pig, Human
WB
Biotin Conjugated
100 µl/$319; 200 µl/$365; 500 µl/$519; 1 ml/$596; 2 ml/$824; 5 ml/$1,348
SORT1 / Sortilin Antibody - Western blot of SORT1 / Sortilin antibody.
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SORT1 / Sortilin Rabbit anti-Human Polyclonal (aa50-320) (FITC) Antibody
Pig, Human
WB
FITC Conjugated
100 µl/$348; 200 µl/$407; 500 µl/$605; 1 ml/$755; 2 ml/$993; 5 ml/$1,716
SORT1 / Sortilin Antibody - Western blot of SORT1 / Sortilin antibody.
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SORT1 / Sortilin Rabbit anti-Human Polyclonal (aa50-320) (Cy3) Antibody
Pig, Human
WB
Cy3 Conjugated
100 µl/$407; 200 µl/$491; 500 µl/$850; 1 ml/$1,008; 2 ml/$1,308; 5 ml/$2,451
SORT1 / Sortilin Antibody - Western blot of SORT1 / Sortilin antibody.
Select
SORT1 / Sortilin Rabbit anti-Human Polyclonal (aa50-320) (PE) Antibody
Pig, Human
WB
PE Conjugated
100 µl/$407; 200 µl/$491; 500 µl/$850; 1 ml/$1,008; 2 ml/$1,308; 5 ml/$2,451
Select
SORT1 / Sortilin Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IP, WB
Unconjugated
100 µg/$341
SORT1 / Sortilin Antibody - Human Brain, Cerebellum: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
Neuroscience
SORT1 / Sortilin Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC-P
Unconjugated
50 µg/$460
SORT1 / Sortilin Antibody - Rabbit antibody to Sortilin. IHC on rat brain using Rabbit antibody to extracellular, N-terminal part of Sortilin (Neurotensin receptor 3, NTR3, Sort1): IgG at a concentration of 10 ug/ml. Pre-absorption of the antibody with the immunizing peptide completely abolishes the immunostaining (not shown).
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SORT1 / Sortilin Rabbit anti-Rat Polyclonal (N-Terminus) Antibody
Mouse, Rat
IHC, WB
Unconjugated
500 µg/$393
SORT1 / Sortilin Antibody
Select
SORT1 / Sortilin Rabbit anti-Human Polyclonal Antibody
Human
IHC, IHC-P, WB
Unconjugated
50 µl/$286; 100 µl/$321
Select
SORT1 / Sortilin Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
IHC, WB
Unconjugated
500 µg/$393
Select
SORT1 / Sortilin Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
SORT1 / Sortilin Antibody - Immunohistochemistry of paraffin-embedded Human breast cancer using SORT1 Polyclonal Antibody at dilution of 1:40.
Select
SORT1 / Sortilin Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
Select
SORT1 / Sortilin Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
100 µg/$357
SORT1 / Sortilin Antibody - Western blot analysis of extracts of mouse brain tissue using Sortilin antibody. The lane on the left was treated with blocking peptide.
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SORT1 / Sortilin Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
Select
SORT1 / Sortilin Rabbit anti-Human Polyclonal (Extracellular Domain) Antibody
Mouse, Rat, Human
IHC
Unconjugated
100 µl/$688
Select
SORT1 / Sortilin Sheep anti-Rat Polyclonal (N-Terminus) Antibody
Mouse, Rat
IHC, WB
Unconjugated
500 µg/$393
SORT1 / Sortilin Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control. (Left lane) or pCMV6-ENTRY SORT1. (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates. (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-SORT1. (1:500)
Select
SORT1 / Sortilin Mouse anti-Human Monoclonal (aa34-300) (OTI3H4) Antibody
Human
WB
Unconjugated
100 µl/$434
SORT1 / Sortilin Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control. (Left lane) or pCMV6-ENTRY SORT1. (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates. (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-SORT1. (1:500)
Select
SORT1 / Sortilin Mouse anti-Human Monoclonal (aa34-300) (Carrier-free) (OTI3H4) Antibody
Human
WB
Unconjugated, Carrier-free
100 µg/$511
Viewing 1-25 of 35 product results


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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).